scholarly journals SP318PSYCHOMETRIC EVALUATION OF THE SHORT FORM 36 (SF-36) AND THE FUNCTIONAL ASSESSMENT OF CANCER THERAPY-ANEMIA (FACT-AN) IN DIALYSIS AND NON-DIALYSIS PATIENTS WITH ANAEMIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE (CKD)

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i196-i196
Author(s):  
Frederic Finkelstein ◽  
Floortje Van Nooten ◽  
Ingela Wiklund ◽  
Dylan Trundell ◽  
David Cella
Keyword(s):  
Chronic Kidney Disease ◽  
Cancer Therapy ◽  
Kidney Disease ◽  
Functional Assessment ◽  
Short Form ◽  
Dialysis Patients ◽  
Short Form 36 ◽  
Sf 36

scholarly journals Functional Assessment of Cancer Therapy Bone Marrow Transplantation: tradução e validação

2007 ◽  
Vol 41 (2) ◽  
pp. 260-268 ◽  
Author(s):  
Ana Paula Mastropietro ◽  
Érika Arantes de Oliveira ◽  
Manoel Antônio dos Santos ◽  
Júlio César Voltarelli
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Cancer Therapy ◽  
Health Survey ◽  
Functional Assessment ◽  
Marrow Transplantation ◽  
Short Form ◽  
Short Form 36 ◽  
Sf 36 ◽  
Post Hoc

OBJETIVO: Traduzir para o português e validar o questionário de qualidade de vida Functional Assessment of Cancer Therapy - Bone Marrow Transplantation (FACT-BMT) em pacientes transplantados de medula óssea. OBJETIVO: O estudo foi realizado em Ribeirão Preto, SP, em 2005. O FACT-BMT (versão 3) traduzido e a versão em português do Short Form-36 Health Survey (SF-36) foram aplicados simultaneamente em 55 pacientes consecutivos com leucemia, submetidos ao transplante e em seguimento. Dois parâmetros clínicos foram utilizados para testar a sensibilidade do questionário: tempo decorrido do transplante e presença ou não de doença do enxerto contra o hospedeiro. Foi utilizada a análise de variância (ANOVA) com o teste post hoc de Tukey. Aplicou-se o coeficiente alfa de Cronbach, padronizado para todas as questões, escore final e domínios. RESULTADOS: A média de idade dos pacientes foi 34,8±8,1 anos, com escolaridade média de 10,8±4,7 anos, sendo 78,1% do sexo feminino. A duração média de tempo pós-transplante foi de 29,8±32,19 meses. Nenhuma alteração do formato original do questionário foi observada no final do processo de tradução e adaptação cultural. A consistência interna foi alta (0,88). A correlação entre o questionário traduzido e o SF-36 variou de 0,35 a 0,57, considerada de moderada a boa para a maioria dos domínios de qualidade de vida. A avaliação das validades de construto e concorrente foi satisfatória e estatisticamente significativa. CONCLUSÕES: A versão para o português do FACT-BMT foi validada satisfatoriamente para a aplicação em pacientes brasileiros de ambos os sexos submetidos ao transplante de medula óssea.

scholarly journals Validity and internal consistency of EQ-5D-3L quality of life tool among pre-dialysis patients with chronic kidney disease in Sri Lanka, a lower middle-income country

2019 ◽  
Author(s):  
Sameera Senanayake ◽  
PKB Mahesh ◽  
Nalika Gunawardena ◽  
Nicholas Graves ◽  
Sanjeewa Kularatna
Keyword(s):  
Chronic Kidney Disease ◽  
Psychological Distress ◽  
Sri Lanka ◽  
Kidney Disease ◽  
Internal Consistency ◽  
Short Form ◽  
Economic Evaluations ◽  
Cronbach Alpha ◽  
Sf 36 ◽  
D 20

AbstractObjectiveEQ-5D-3L is a generic QOL tool used mainly in economic evaluations. Burden of Chronic Kidney Disease (CKD) is rising in Sri Lanka. Assessing the validity of generic QOL tools creates new opportunities of their utilization among patients with CKD.MethodsA cross-sectional study was conducted among 1036 CKD patients, selected using the simple random sampling technique. The validity was tested with six a-priori hypotheses. These included construct validity assessments, evaluating convergent validity and performing known group comparisons. EQ-5D-3L, Short Form-36 (SF-36), Center for Epidemiological Studies Depression Scale (CES-D-20) and General Health Questionnaire-12 (GHQ-12) were used to assess QOL, presence of depression and psychological distress respectively. Internal consistency of the whole tool and when each item is removed was assessed by Cronbach alpha.ResultsThe response rate was 99.2%. Majority of participants were males (n=646,62.4%) in the age category of 41-60 (n=530; 51.2%). Most were in either stage 4 or 5 of CKD (n=646,75.1%). The summary measures of SF-36, positively and significantly correlated with the EQ-5D-3L index and VAS scores (p<0.001). EQ-5D-3L QOL scores were significantly different between the group with depression and without as measured by CES-D-20 (p<0.001). Assessed using GHQ-12, similar significance was detected between the group with psychological distress and without (p<0.001). The Cronbach alpha was 0.834 and when each item was removed, ranged from 0.782 to 0.832.ConclusionEQ-5D-3L is a valid generic QOL tool with satisfactory internal consistency to be used among CKD patients in the pre-dialysis stage.

scholarly journals AN EVALUATION OF NUTRITIONAL INDEXES FOR TO PREDICTION THE HOSPITALIZATION DURATION IN ELDERLY CHRONIC KIDNEY DISEASE PATIENTS

2016 ◽  
pp. 1-4
Author(s):  
B. Buyukaydin ◽  
A.T. Isik ◽  
P. Soysal ◽  
M. Alay ◽  
R. Kazancioglu
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Nutritional Assessment ◽  
Short Form ◽  
Risk Index ◽  
Mini Nutritional Assessment ◽  
Nutritional Risk ◽  
Control Group ◽  
Dialysis Patients ◽  
Nutritional Risk Index

Objective: Chronic kidney disease and malnutrition are serious and frequently encountered co-morbidities among older patients. We evaluated nutritional status of older pre-dialysis patients and the effect of malnutrition on length of stay (LOS) in hospital. Materials and Methods: 65 years and over 33 hospitalized pre-dialysis patients with glomerular filtration rate between 10-30ml/min/1.73m2 were included. There is no control group. For all patients, biochemical analysis was performed. The malnutrition risk was evaluated with Mini Nutritional Assessment Short-Form (MNA-SF) and Geriatric Nutritional Risk Index (GNRI) and LOS in hospital was recorded. Results: Mean GNRI was 98.4±12.9 and the mean MNA-SF was 8±3.15. For all patients, mean LOS was 10.58±9 days. According to MNA-SF, malnourished patients’ LOS was longer and a difference was observed between MNA-SF and GNRI in terms of LOS prediction (p=0.005, p=0.230). Conclusion: For older pre-dialysis patients, MNA-SF is probably a more sensitive index in terms of LOS in hospital prediction.

Peripheral neuropathy: an important contributor to physical limitation and morbidity in stages 3 and 4 chronic kidney disease

2021 ◽  
Author(s):  
Ria Arnold ◽  
Timothy J Pianta ◽  
Tushar Issar ◽  
Adrienne Kirby ◽  
Caoimhe M K Scales ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Peripheral Neuropathy ◽  
Kidney Disease ◽  
Physical Function ◽  
Walking Speed ◽  
Short Form ◽  
Important Contributor ◽  
Diabetes Status ◽  
Sf 36 ◽  
Patient Reported

Abstract Background Impaired physical function drives adverse outcomes in chronic kidney disease (CKD). Peripheral neuropathy is highly prevalent in CKD, though its contribution to physical function in CKD patients is unknown. This study examined the relationships between peripheral neuropathy, walking speed and quality of life (QoL) in stages 3 and 4 CKD. Methods This was a prospective observational study investigating neuropathy in CKD patients with an estimated glomerular filtration rate (eGFR) 15–60 mL/min/1.73 m2. A total of 109 patients were consecutively recruited. The presence and severity of peripheral neuropathy was determined using the total neuropathy score. Walking speed was assessed at both usual and maximal speed, and QoL was assessed using the Short- Form 36 (SF-36) questionnaire. Results Peripheral neuropathy was highly prevalent: 40% demonstrated mild neuropathy and 37% had moderate–severe neuropathy. Increasing neuropathy severity was the primary predictor of reduced walking speed (R2 = −0.41, P &lt; 0.001) and remained so after multivariable analysis adjustment for diabetes. This association was evident for both usual and maximal walking speeds. Neuropathy correlated significantly with low scores on multiple domains of SF-36 including physical function (r = −0.570, P &lt; 0.001). Subanalysis according to diabetic status revealed a high prevalence of neuropathy both with and without diabetes; relationships to walking speed remained evident in subgroup analysis. However, those with diabetes demonstrated greater severity of neuropathy, slower walking speed and lower scores in QoL. Conclusions Moderate to severe peripheral neuropathy was common in stages 3 and 4 CKD, associated with reduced walking speed independent of diabetes status and was correlated with patient-reported QoL. This suggests that neuropathy is an important contributor to declining physical function in CKD irrespective of diabetes status. Targeted diagnosis and management of peripheral neuropathy during CKD progression may improve functional outcomes and QoL.

scholarly journals Comparison of the EQ-5D 3L and the SF-6D (SF-36) contemporaneous utility scores in patients with chronic kidney disease in Sri Lanka: a cross-sectional survey

BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e024854
Author(s):  
Sanjeewa Kularatna ◽  
Sameera Senanayake ◽  
Nalika Gunawardena ◽  
Nicholas Graves
Keyword(s):  
Chronic Kidney Disease ◽  
Sri Lanka ◽  
Kidney Disease ◽  
Short Form ◽  
Classification Systems ◽  
Health State ◽  
Cross Sectional ◽  
Life Years ◽  
Sf 36 ◽  
Utility Scores

ObjectivesThe aim of this study was to compare utility weights of EuroQoL-five-dimension-3 levels (EQ-5D-3L) and Short-Form six-dimension (SF-6D) in a representative cohort of patients with chronic kidney disease (CKD). A cost–utility analysis (CUA) is designed to report the change to costs required to achieve an estimated change to quality-adjusted life years (QALYs). The quality component of a QALY is measured by utility. Utility represents the preference of general population for a given health state. Classification systems of the multi-attribute utility instruments (MAUIs) are used to define these health states. Utility weights developed from different classification systems can vary and may affect the conclusions from CUAs.DesignA community-based cross-sectional study.SettingAnuradhapura, a rural district in Sri Lanka.ParticipantsA representative sample of 1096 patients with CKD, selected using the population-based CKD register, completed the EQ-5D-3L and SF-36. SF-6D was constructed from the SF-36 according to the published algorithm. The study assessed discrimination, correlation and differences across the two instruments.ResultsStudy participants were predominantly male (62.6%). Mean EQ-5D-3L utility score was 0.540 (SD 0.35) compared with 0.534 (SD 0.09) for the SF-6D (p=0.588). The correlation (r) between the scores was 0.40 (p<0.001). Utility scores were significantly different in both males and females between the two tools, but there was no difference in age and educational categories. Both MAUI scores were significantly lower (p<0.001) among those who were in more advanced stages of the disease and the corresponding utility scores of the two instruments in different CKD stages were also significantly different (p<0.05). The largest effect size was seen among the patients on dialysis.ConclusionsThe correlation between the scores was moderate. SF-6D had the lowest floor and ceiling effect and was better at detecting different stages of the disease. Thus, based on the evidence presented in this study, SF-6D appears to be more appropriate to be used among patients with CKD.

scholarly journals Fatores associados com a qualidade de vida relacionada à saúde de idosos em hemodiálise

2011 ◽  
Vol 45 (6) ◽  
pp. 1127-1136 ◽  
Author(s):  
Sonia Faria Mendes Braga ◽  
Sérgio Viana Peixoto ◽  
Isabel Cristina Gomes ◽  
Francisco de Assis Acúrcio ◽  
Eli Iola Gurgel Andrade ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Kidney Disease ◽  
Short Form ◽  
Medical Outcome ◽  
Short Form 36 ◽  
Sf 36 ◽  
Belo Horizonte

OBJETIVO: Identificar fatores associados à qualidade de vida relacionada à saúde de pacientes idosos em hemodiálise. MÉTODOS: Estudo transversal com 223 pacientes com idade > 60 anos em hemodiálise nas unidades de diálise do município de Belo Horizonte, MG, em 2008. A qualidade de vida foi avaliada utilizando o Kidney Disease and Quality of Life - Short Form (KDQOL-SF) e o Medical Outcome Survey - Short Form 36 (SF-36). Os três escores do KDQOL-SF medidos foram: componente da doença renal sumarizado (11 subescalas), componente físico sumarizado (quatro subescalas) e componente mental sumarizado (quatro subescalas). RESULTADOS: Foram observadas associações negativas significativas e independentes do componente da doença renal e mental com número de doenças crônicas e tempo de tratamento (ambas). O componente físico foi menor entre os mais velhos, as mulheres, aqueles com maior número de internações e com três ou mais doenças crônicas. CONCLUSÕES: A associação consistente com presença de doenças crônicas mostra a importância do perfil de morbidade para a qualidade de vida dessa população. A identificação dos fatores associados, como aumento da idade, sexo feminino, número de internações e tempo de tratamento, pode favorecer o planejamento adequado das ações de saúde para melhor atender a esse grupo.

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