SP614ANNUAL VARIATION OF GERIATRIC NUTRITIONAL RISK INDEX IS AN ACCURATE PROGNOSTIC FACTOR IN DIALYSIS PATIENT

BackgroundThe Geriatric Nutritional Risk Index (GNRI) might be a useful screening tool for malnutrition in dialysis patients. However, data concerning the GNRI as a prognostic factor in peritoneal dialysis (PD) patients are scarce.MethodsWe reviewed the medical records at Yeungnam University Hospital in Korea to identify all adults (>18 years) who received PD; 486 patients were enrolled in the study.ResultsThe initial low, middle, and high GNRI tertiles included 162, 166, and 158 patients respectively. Significant correlations were noted between the initial GNRI and body mass index, creatinine, albumin, arm circumference, fat mass index, and comorbidities. The cut-off value for the time-averaged GNRI over 1 year was 96.4, and the sensitivity and specificity for a diagnosis of a decline in lean mass were 77.1% and 40.0% respectively. A multivariate analysis adjusted for age, risk according to the Davies comorbidity index, and C-reactive protein showed that an low initial GNRI tertile was associated with mortality in PD patients.ConclusionsThe GNRI is a simple method for predicting nutrition status and clinical outcome in PD patients.

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Geriatric nutritional risk index as a useful prognostic factor in second allogeneic hematopoietic stem cell transplantation

Annals of Hematology ◽

10.1007/s00277-020-04089-0 ◽

2020 ◽

Vol 99 (7) ◽

pp. 1655-1665 ◽

Cited By ~ 1

Author(s):

Satoshi Kaito ◽

Atsushi Wada ◽

Hiroto Adachi ◽

Ryosuke Konuma ◽

Yuya Kishida ◽

...

Keyword(s):

Stem Cell ◽

Prognostic Factor ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Risk Index ◽

Nutritional Risk ◽

Geriatric Nutritional Risk Index ◽

Hematopoietic Stem ◽

Nutritional Risk Index

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The prognostic significance of combined geriatric nutritional risk index and psoas muscle volume in older patients with pancreatic cancer

BMC Cancer ◽

10.1186/s12885-021-08094-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Teruhisa Sakamoto ◽

Takuki Yagyu ◽

Ei Uchinaka ◽

Kozo Miyatani ◽

Takehiko Hanaki ◽

...

Keyword(s):

Pancreatic Cancer ◽

Prognostic Factor ◽

Assessment Tool ◽

Risk Index ◽

Prognostic Significance ◽

Psoas Muscle ◽

Muscle Volume ◽

Nutritional Risk ◽

Geriatric Nutritional Risk Index ◽

Nutritional Risk Index

Abstract Background The geriatric nutritional risk index (GNRI), originally developed as a nutritional assessment tool to evaluate mortality and morbidity in older hospitalized patients (i.e., those aged ≥65 years), is regarded as a prognostic factor in several cancers. Body composition is also an important consideration when predicting the prognosis of patients with cancer. This study aimed to investigate the relationship between the GNRI and psoas muscle volume (PMV) for survival outcomes in patients with pancreatic cancer. Methods This retrospective study evaluated the prognostic significance of the GNRI and PMV in 105 consecutive patients aged ≥65 years who underwent pancreatectomy for histologically confirmed pancreatic cancer. The patients were divided into high (GNRI > 98) and low GNRI groups (GNRI ≤98), and into high (PMV > 61.5 mm3/m3 for men and 44.1 mm3/m3 for women) and low PMV (PMV ≤ 61.5 mm3/m3 for men and 44.1 mm3/m3 for women) groups. Results Both the 5-year overall survival (OS) and recurrence-free survival (RFS) rates were significantly greater among patients in the high GNRI group than among patients in the low GNRI group. Similarly, both the 5-year OS and RFS rates were significantly greater among patients in the high PMV group than among patients in the low PMV group. Patients were stratified into three groups: those with both high GNRI and high PMV; those with either high GNRI or high PMV (but not both); and those with both low GNRI and low PMV. Patients with both low GNRI and low PMV had a worse 5-year OS rate, compared with patients in other groups (P < 0.001). The C-index of the combination of the GNRI and PMV for predicting 5-year OS was greater than the C-indices of either the GNRI or PMV alone. Multivariate analysis revealed that the combination of the GNRI and PMV was an independent prognostic factor in patients aged ≥65 years with pancreatic cancer (P = 0.003). Conclusions The combination of the GNRI and PMV might be useful to predict prognosis in patients aged ≥65 years with pancreatic cancer.

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