scholarly journals Role of the Infectious Disease Consultant in Management of Patients With Tuberculosis-Associated Ocular Inflammation

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Marjorie M. Conant ◽  
Chuck R. Vrasich ◽  
Jeff V. Wongskhaluang ◽  
Kevin Ferenchak ◽  
Matthew K. Asano ◽  
...  

Abstract Background.  Tuberculosis is a disease with continued worldwide prevalence, morbidity, and mortality. Tuberculosis-associated ocular inflammation (TB-AOI) is a manifestation that can occur with pulmonary or extrapulmonary TB. Evaluation of these ocular presentations and treatment in the United States are limited. Our objective was to describe cases in an urban area and assess the role of the infectious diseases specialist in managing these complex patients. Methods.  We performed a retrospective case series of all patients referred to our infectious disease clinic for presumed TB-AOI from 2005 through 2013. Patients with ocular inflammation were determined to have presumed TB-AOI based on clinical presentation with correlative positive tuberculin skin test and/or QuantiFERON-TB Gold. Attempts were made to exclude other diagnoses. Data were collected and analyzed with respect to demographics, ocular manifestations, and treatment. Results.  Sixty eyes of 42 patients were included in the study; anterior uveitis was the most common site of involvement. The median age was 46 years, and 33 patients (79%) were foreign born. Forty patients (95%) received a course of antituberculous therapy with 38% experiencing treatment-related side effects. A 6-month duration was recommended in 78% cases. There was improvement or stability of the vision in 42 eyes (74%) of those treated. Conclusions.  Ocular involvement is an uncommon but important manifestation of TB. Our data further characterize TB-AOI cases in the United States. Treatment provides significant benefit to properly selected patients. A multidisciplinary approach, with care provided by ophthalmology and infectious disease providers, should be used to allow for the most efficacious treatment.

2007 ◽  
Vol 41 (2) ◽  
pp. 466-479 ◽  
Author(s):  
Katherine Hempstead

This study uses the 2000 PUMS to examine mobility among the foreign-born population and the role of the gateway states. Between 1995 and 2000, net domestic migration of the foreign-born population to gateway states was negative. Yet the rate of out-migration from gateway states was lower than that from non-gateway states. Overall, the findings do not support the idea that gateway states are “losing their hold” on their foreign-born population. Yet trends in international and domestic migration are increasing the foreign-born population of non-gateway states relative to gateway states, and reducing differences in their characteristics.


2021 ◽  
pp. 089011712110344
Author(s):  
Adolfo G. Cuevas ◽  
Michael V. Stanton ◽  
Keri Carvalho ◽  
Natalie Eckert ◽  
Kasim Ortiz ◽  
...  

Purpose: Obesity is a public health issue in the United States (US), that disproportionately affects marginalized group members. Stressful life events (SLE) have been implicated as an obesogenic risk factor. However, there is scant research examining of the role of nativity status and length of residence in the relationship between SLE and obesity. Design: Cross-sectional survey. Setting: Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions. Sample: A total of 34,653 participants were included in these analyses, of whom 10,169 (29.39%) had obesity. Measures: Obesity (measured using body mass index), stressful life events, race/ethnicity, gender, educational attainment, family income, marital status, current smoking status, and alcohol abuse. Analysis: Weighted logistic regression analysis. Results: A total of 10,169 (29.39%) had obesity. There was a significant interaction between SLE and nativity status/length of residence [F (3, 34,642) = 60.50, p < 0.01]. Based on stratified analyses, SLE were associated with greater odds of obesity for US-born individuals (OR = 1.07; 95% CI [1.05, 1.08]) and foreign-born individuals living in the US for ≥ 20 years (OR = 1.17; 95% CI [1.10, 1.25]). There was no evidence that SLE were associated with greater odds of obesity for foreign-born individuals living in the US <10 years (OR = 1.06; 95% CI [0.94, 1.21]) and 11-19 years (OR = 1.00; 95% CI [0.91, 1.09]). Conclusions: Number of SLE may be a risk factor for obesity, particularly for US-born adults and foreign-born adults living the US >20 years. Further research is needed to understand the pathways that may link SLE to obesity among these groups.


2021 ◽  
Vol 19 (2) ◽  
pp. 147470492110215
Author(s):  
Robert K. Henderson ◽  
Simone Schnall

Prior research has indicated that disease threat and disgust are associated with harsher moral condemnation. We investigated the role of a specific, highly salient health concern, namely the spread of the coronavirus, and associated COVID-19 disease, on moral disapproval. We hypothesized that individuals who report greater subjective worry about COVID-19 would be more sensitive to moral transgressions. Across three studies ( N = 913), conducted March-May 2020 as the pandemic started to unfold in the United States, we found that individuals who were worried about contracting the infectious disease made harsher moral judgments than those who were relatively less worried. This effect was not restricted to transgressions involving purity, but extended to transgressions involving harm, fairness, authority, and loyalty, and remained when controlling for political orientation. Furthermore, for Studies 1 and 2 the effect also was robust when taking into account the contamination subscale of the Disgust Scale–Revised. These findings add to the growing literature that concrete threats to health can play a role in abstract moral considerations, supporting the notion that judgments of wrongdoing are not based on rational thought alone.


2008 ◽  
Vol 20 (3) ◽  
pp. 97-105 ◽  
Author(s):  
Smita C. Banerjee ◽  
Kathryn Greene ◽  
Marina Krcmar ◽  
Zhanna Bagdasarov ◽  
Dovile Ruginyte

This study demonstrates the significance of individual difference factors, particularly gender and sensation seeking, in predicting media choice (examined through hypothetical descriptions of films that participants anticipated they would view). This study used a 2 (Positive mood/negative mood) × 2 (High arousal/low arousal) within-subject design with 544 undergraduate students recruited from a large northeastern university in the United States. Results showed that happy films and high arousal films were preferred over sad films and low-arousal films, respectively. In terms of gender differences, female viewers reported a greater preference than male viewers for happy-mood films. Also, male viewers reported a greater preference for high-arousal films compared to female viewers, and female viewers reported a greater preference for low-arousal films compared to male viewers. Finally, high sensation seekers reported a preference for high-arousal films. Implications for research design and importance of exploring media characteristics are discussed.


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