Activation of Magnesium-Dependent, Neutral Sphingomyelinase by Phosphatidylserine

Faculty Opinions recommendation of Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009844.136857 ◽

2002 ◽

Author(s):

Stefan Bräse

Keyword(s):

Irreversible Inhibitors

Faculty Opinions recommendation of Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021915.249623 ◽

2004 ◽

Author(s):

George Perry

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Nadph Oxidase ◽

Amyloid Beta ◽

Primary Neurons ◽

Amyloid Beta Peptides ◽

Beta Peptides

Regulatory T cells reduce endothelial neutral sphingomyelinase 2 to prevent T cell migration into tumors

European Journal of Immunology ◽

10.1002/eji.202149208 ◽

2021 ◽

Author(s):

Paulina Akeus ◽

Louis Szeponik ◽

Veronica Langenes ◽

Viktoria Karlsson ◽

Patrik Sundström ◽

...

Keyword(s):

T Cells ◽

Cell Migration ◽

T Cell ◽

Regulatory T Cells ◽

T Cell Migration

Physiological functions and therapeutic applications of neutral sphingomyelinase and acid sphingomyelinase

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2021.111610 ◽

2021 ◽

Vol 139 ◽

pp. 111610

Author(s):

Hongjiao Xiang ◽

Shengjie Jin ◽

Fenglang Tan ◽

Yifan Xu ◽

Yifei Lu ◽

...

Keyword(s):

Acid Sphingomyelinase ◽

Physiological Functions ◽

Therapeutic Applications ◽

Scyphostatin, a Neutral Sphingomyelinase Inhibitor from a Discomycete, Trichopeziza mollissima: Taxonomy of the Producing Organism, Fermentation, Isolation, and Physico-chemical roperties.

The Journal of Antibiotics ◽

10.7164/antibiotics.52.525 ◽

1999 ◽

Vol 52 (6) ◽

pp. 525-530 ◽

Cited By ~ 88

Author(s):

FUTOSHI NARA ◽

MASAHIRO TANAKA ◽

TSUYOSHI HOSOYA ◽

KEIKO SUZUKI-KONAGAI ◽

TAKESHI OGITA

Keyword(s):

Physico Chemical

Neutral sphingomyelinase‐2 and cardiometabolic diseases

Obesity Reviews ◽

10.1111/obr.13248 ◽

2021 ◽

Author(s):

Sardar Sindhu ◽

Yat Hei Leung ◽

Hossein Arefanian ◽

S. R. Murthy Madiraju ◽

Fahd Al‐Mulla ◽

...

Keyword(s):

Cardiometabolic Diseases ◽

Synthesis and Evaluation of Three Novel Scyphostatin Analogues as Neutral Sphingomyelinase Inhibitors

ChemBioChem ◽

10.1002/cbic.200300667 ◽

2003 ◽

Vol 4 (11) ◽

pp. 1223-1225 ◽

Cited By ~ 21

Author(s):

Emmanuel N. Pitsinos ◽

Veit Wascholowski ◽

Sevasti Karaliota ◽

Chrisoula Rigou ◽

Elias A. Couladouros ◽

...

Keyword(s):

Interaction with Factor Associated with Neutral Sphingomyelinase Activation, a WD Motif-Containing Protein, Identifies Receptor for Activated C-Kinase 1 as a Novel Component of the Signaling Pathways of the p55 TNF Receptor

The Journal of Immunology ◽

10.4049/jimmunol.169.9.5161 ◽

2002 ◽

Vol 169 (9) ◽

pp. 5161-5170 ◽

Cited By ~ 35

Author(s):

Anna Ewgenjewna Tcherkasowa ◽

Sabine Adam-Klages ◽

Marie-Luise Kruse ◽

Katja Wiegmann ◽

Sabine Mathieu ◽

...

Keyword(s):

Signaling Pathways ◽

Tnf Receptor ◽

Identification and evaluation of neutral sphingomyelinase 2 inhibitors

Archives of Pharmacal Research ◽

10.1007/s12272-011-0208-y ◽

2011 ◽

Vol 34 (2) ◽

pp. 229-236 ◽

Cited By ~ 10

Author(s):

Dong Hun Lee ◽

Sung Hyun Kim ◽

Kyong Hoon Ahn ◽

Seok Kyun Kim ◽

Jong Min Choi ◽

...

Keyword(s):

Synthesis and Antiapoptotic Activity of a Novel Analogue of the Neutral Sphingomyelinase Inhibitor Scyphostatin

ChemBioChem ◽

10.1002/cbic.200400228 ◽

2005 ◽

Vol 6 (4) ◽

pp. 726-737 ◽

Cited By ~ 16

Author(s):

Ralf A. Claus ◽

Annette Wüstholz ◽

Stefan Müller ◽

Clemens L. Bockmeyer ◽

Norman H. Riedel ◽

...

Keyword(s):

Antiapoptotic Activity