scholarly journals Comparison of the effects of infection with Salmonella enteritidis, in combination with an induced molt, on serum levels of the acute phase protein, alpha1 acid glycoprotein, in hens

2002 ◽  
Vol 81 (9) ◽  
pp. 1295-1300 ◽  
Author(s):  
PS Holt ◽  
RK Gast
1992 ◽  
Vol 262 (5) ◽  
pp. R786-R793 ◽  
Author(s):  
R. J. Sharma ◽  
D. C. Macallan ◽  
P. Sedgwick ◽  
D. G. Remick ◽  
G. E. Griffin

The kinetics of cytokine release and acute-phase protein gene expression in liver were investigated in rats receiving a single intraperitoneal bolus dose of Escherichia coli lipopolysaccharide (LPS). Transient elevation of plasma tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) were detected. Hepatic messenger RNAs for two acute-phase proteins, alpha 1-acid glycoprotein and alpha 2-macroglobulin, were measured by Northern blotting and were found to increase to a maximum at 24 h, returning to normal by 72 h; plasma concentrations showed a slower but more sustained rise. For albumin, hepatic mRNA was reduced, being minimum at 24 h with a similar but more prolonged fall in plasma concentration. Pretreatment of rats with TNF-alpha monoclonal antibody 4 h before LPS ameliorated weight loss and anorexia, partially suppressed the rise in IL-6 and reduced the increase in hepatic mRNA and plasma concentrations of alpha 1-acid glycoprotein and alpha 2-macroglobulin. For albumin, however, such pretreatment had no effect on the fall in either hepatic mRNA or plasma concentration. Thus we have defined an in vivo role of TNF-alpha in the control of endotoxin-induced acute-phase protein generation.


2004 ◽  
Vol 99 (3-4) ◽  
pp. 229-236 ◽  
Author(s):  
Fabrizio Ceciliani ◽  
Claudia Grossi ◽  
Alessia Giordano ◽  
Vanessa Pocacqua ◽  
Saverio Paltrinieri

Immunobiology ◽  
2019 ◽  
Vol 224 (5) ◽  
pp. 672-680 ◽  
Author(s):  
Mosale Seetharam Sumanth ◽  
Kandahalli Venkataranganayaka Abhilasha ◽  
Shancy Petsel Jacob ◽  
Vyala Hanumanthareddy Chaithra ◽  
Venkatesha Basrur ◽  
...  

2019 ◽  
Vol 235 ◽  
pp. 93-100 ◽  
Author(s):  
Gabriele Meroni ◽  
Valentina Zamarian ◽  
Cristina Prussiani ◽  
Valerio Bronzo ◽  
Cristina Lecchi ◽  
...  

2003 ◽  
Vol 14 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Tino Hochepied ◽  
Franklin G Berger ◽  
Heinz Baumann ◽  
Claude Libert

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