Elucidation of HIV‐1 5' Leader Secondary Structure Through Novel Long Range Nuclear Magnetic Resonance (NMR) Techniques

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Claudia Walker ◽  
Elisabeth Kan ◽  
Faith Davis ◽  
Jonathan Catazaro ◽  
Michael Summers
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Secondary Structure ◽  
Long Range ◽  
Nmr Techniques ◽  
Hiv 1 ◽  
Nuclear Magnetic

Nuclear Magnetic Resonance Spectroscopic Behaviour of Some Selective Natural Flavonoids: A Look Through

2020 ◽  
Vol 17 (2) ◽  
pp. 185-196
Author(s):  
Shyamal K. Jash ◽  
Dilip Gorai ◽  
Lalan C. Mandal ◽  
Rajiv Roy
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Natural Products ◽  
Magnetic Resonance ◽  
Hard Core ◽  
2D Nmr ◽  
Vital Role ◽  
Spectral Technique ◽  
Nmr Techniques ◽  
Significant Class ◽  
Nuclear Magnetic

Flavonoids are considered as a significant class of compounds among the natural products, exhibiting a variety of structural skeletons as well as multidirectional biological potentials. In structural elucidations of natural products, Nuclear Magnetic Resonance (NMR) spectroscopy has been playing a vital role; the technique is one of the sharpest tools in the hands of natural products chemists. The present resume deals with hard-core applications of such spectral technique, particularly in structural elucidation of flavonoids; different NMR techniques including 1H-NMR, 13C-NMR, and 2D-NMR [viz. 1H-1H COSY, COLOC, HMBC, HMQC] are described in detail.

Nuclear Magnetic Resonance Experiments on Acetals. 43. Reversal of Previous Conformational Assignment in 5-Fluoromethylated-5′-Me-1,3-dioxanes

1973 ◽  
Vol 51 (19) ◽  
pp. 3170-3172 ◽  
Author(s):  
M. Anteunis ◽  
F. Borremans
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Long Range ◽  
Double Resonance ◽  
Axial Position ◽  
Nuclear Magnetic

Additional n.m.r. investigations on 5-fluoromethylated-5′-Me-1,3-dioxanes have made it necessary for us to reverse the spectral assignments which were forwarded recently (1) in this journal. Thus, the 5-CF2H group prefers the axial position to the extent of ca. 900 cal/mol, whereas the 5-CFH2 group displays a similar preference for the axial position to the extent of ca. 200 cal/mol. An explanation for these unexpected results is advanced. Final structural assignments have been made possible by homo- and heteronuclear double resonance experiments and by ASIS-studies. The observed relative shifts for 5-CFnH3−n and 5-CH3 signals are shown to be normal (e.g. δ(5e) < δ(5a)). Also, the previously reported 4J(F,H) long range couplings follow a classical M-path.

Sign in / Sign up

Export Citation Format

Share Document