scholarly journals CDC20 and TRIB3 Upregulated by TFAP2C Facilitate Cell Proliferation in Non‐small Cell Lung Cancer Cells

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Dain Kim ◽  
Danbi Seo ◽  
Wanyeon Kim
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Small Cell Lung

scholarly journals Aptamer-miR-34c Conjugate Affects Cell Proliferation of Non-Small-Cell Lung Cancer Cells

2018 ◽  
Vol 13 ◽  
pp. 334-346 ◽  
Author(s):  
Valentina Russo ◽  
Alessia Paciocco ◽  
Alessandra Affinito ◽  
Giuseppina Roscigno ◽  
Danilo Fiore ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Small Cell Lung

scholarly journals Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells

2011 ◽  
Vol 463 (2) ◽  
pp. 365-376 ◽  
Author(s):  
Günter Glassmeier ◽  
Kathrin Hempel ◽  
Iris Wulfsen ◽  
Christiane K. Bauer ◽  
Udo Schumacher ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Protein Expression ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
K Channel ◽  
Small Cell Lung

scholarly journals MiR-222-3p Promotes Cell Proliferation and Inhibits Apoptosis by Targeting PUMA (BBC3) in Non-Small Cell Lung Cancer

2020 ◽  
Vol 19 ◽  
pp. 153303382092255
Author(s):  
Weijun Chen ◽  
Xiaobo Li
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Cell Apoptosis ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Small Cell Lung ◽  
Binding Component

MicroRNAs have been demonstrated to be critical regulators in tumor progression, including non-small cell lung cancer. MicroRNA-222-3p has been reported to function as a tumor suppressor or oncogene in several types of cancer, but its function role in non-small cell lung cancer has not been uncovered. In this study, we first found the expression of microRNA-222-3p was significantly increased in non-small cell lung cancer tissues and cell lines. MicroRNA-222-3p inhibitor decreased the activity of non-small cell lung cancer cells to proliferate and increased cell apoptosis using cell counting kit-8, flow cytometry, and caspase-3 activity analysis. Overexpressed microRNA-222-3p in non-small cell lung cancer cells promoted cell proliferation, but decreased cell apoptosis. Moreover, Bcl-2-binding component 3 was the target gene of microRNA-222-3p, and its knockdown weakened the regulatory effect of microRNA-222-3p inhibitor on cell proliferation and apoptosis in non-small cell lung cancer cells. In conclusion, microRNA-222-3p plays a significant role in the regulation of Bcl-2-binding component 3 expression and might be a promising target for clinical non-small cell lung cancer therapy.

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