scholarly journals RGS7 Protein Suppression of Gao Protein‐Mediated α2A‐Adrenergic Receptor Inhibition of Mouse Hippocampal CA3 Epileptiform Activity

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Brian William Nelson ◽  
Brianna Goldenstein ◽  
Ke Xu ◽  
Elizabeth Luger ◽  
Jenna Wald ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Epileptiform Activity ◽  
Receptor Inhibition ◽  
Hippocampal Ca3

scholarly journals Regulator of G Protein Signaling Protein Suppression of Gαo Protein-Mediated α2A Adrenergic Receptor Inhibition of Mouse Hippocampal CA3 Epileptiform Activity

2009 ◽  
Vol 75 (5) ◽  
pp. 1222-1230 ◽  
Author(s):  
Brianna L. Goldenstein ◽  
Brian W. Nelson ◽  
Ke Xu ◽  
Elizabeth J. Luger ◽  
Jacquline A. Pribula ◽  
...  
Keyword(s):  
G Protein ◽  
Adrenergic Receptor ◽  
Epileptiform Activity ◽  
G Protein Signaling ◽  
Protein Signaling ◽  
Signaling Protein ◽  
Receptor Inhibition ◽  
Hippocampal Ca3

α2A Adrenergic Receptor Activation Inhibits Epileptiform Activity in the Rat Hippocampal CA3 Region

2007 ◽  
Vol 71 (6) ◽  
pp. 1572-1581 ◽  
Author(s):  
Chris W. D. Jurgens ◽  
Hana M. Hammad ◽  
Jessica A. Lichter ◽  
Sarah J. Boese ◽  
Brian W. Nelson ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Epileptiform Activity ◽  
Receptor Activation ◽  
Hippocampal Ca3 ◽  
Ca3 Region

scholarly journals Pharmacological characterization of the α 2 adrenergic receptor inhibiting mouse hippocampal CA3 epileptiform activity

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Brian Nelson ◽  
Brianna Goldenstein ◽  
Ke Xu ◽  
Elizabeth Luger ◽  
Jacquline Pribula ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Epileptiform Activity ◽  
Pharmacological Characterization ◽  
Hippocampal Ca3

PROPRANOLOL (INDERAL) IN EXPERIMENTALLY-INDUCED CARDIAC ARRHYTHMIAS

1966 ◽  
Vol 44 (4) ◽  
pp. 543-547 ◽  
Author(s):  
B. R. Lucchesi ◽  
L. S. Whitsitt ◽  
N. L. Brown
Keyword(s):  
Ventricular Tachycardia ◽  
Cardiac Arrhythmias ◽  
Adrenergic Receptor ◽  
Antiarrhythmic Activity ◽  
Receptor Blockade ◽  
Beta Adrenergic Receptor ◽  
Beta Adrenergic ◽  
Sympathomimetic Amine ◽  
Receptor Inhibition ◽  
Experimentally Induced

Propranolol (Inderal), a new, potent, non-carcinogenic beta adrenergic receptor antagonist has been shown to possess antiarrhythmic activity when tested against experimentally induced cardiac arrhythmias. The potent beta adrenergic receptor inhibition produced by propranolol leads to a prevention of those cardiac arrhythmias resulting from a combination of a sensitizing agent and a sympathomimetic amine. Methylchloroform–adrenaline and U-0882–isoproterenol arrhythmias were prevented by previous administration of propranolol at a dose sufficient to produce beta adrenergic receptor blockade.Propranolol has been shown to be capable of reversing ventricular tachycardia associated with ouabain intoxication in the anesthetized dog. The agent exerts an effect upon the ouabain-induced ventricular automatic focus and abolishes the activity of the abnormal pacemaker. The mechanism, although unknown, is not believed to be associated with the ability of propranolol to produce beta adrenergic receptor blockade.

scholarly journals Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition

2020 ◽  
Vol 7 (6) ◽  
pp. 883-890 ◽  
Author(s):  
Sukhvir K. Wright ◽  
Max A. Wilson ◽  
Richard Walsh ◽  
William B. Lo ◽  
Nilesh Mundil ◽  
...  
Keyword(s):  
Human Brain ◽  
Brain Tissue ◽  
Ampa Receptor ◽  
Epileptiform Activity ◽  
Human Brain Tissue ◽  
Receptor Inhibition

scholarly journals Carbonic Anhydrase Inhibitor Sulthiame Reduces Intracellular pH and Epileptiform Activity of Hippocampal CA3 Neurons

Epilepsia ◽  
2002 ◽  
Vol 43 (5) ◽  
pp. 469-474 ◽  
Author(s):  
Tobias Leniger ◽  
Martin Wiemann ◽  
Dieter Bingmann ◽  
Guido Widman ◽  
Andreas Hufnagel ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Intracellular Ph ◽  
Epileptiform Activity ◽  
Carbonic Anhydrase Inhibitor ◽  
Hippocampal Ca3 ◽  
Ca3 Neurons
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