Discovery of selective inhibitors of fibroblast growth factor receptor 1 kinase with potent anti‐human lung carcinoma activity

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.601.6 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Guang Liang ◽

Yi Wang ◽

Huiping Zhou ◽

Xiaokun Li

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Lung Carcinoma ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors ◽

Human Lung Carcinoma

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Potent, Selective Inhibitors of Fibroblast Growth Factor Receptor Define Fibroblast Growth Factor Dependence in Preclinical Cancer Models

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-11-0426 ◽

2011 ◽

Vol 10 (9) ◽

pp. 1542-1552 ◽

Author(s):

Matthew Squires ◽

George Ward ◽

Gordan Saxty ◽

Valerio Berdini ◽

Anne Cleasby ◽

...

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors ◽

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Programmed cell death-1 (PD-L1) expression and Fibroblast growth factor receptor 1 (FGFR1) amplification in Chinese stage III/IV lung squamous lung carcinoma (SQC).

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.15_suppl.e19127 ◽

2015 ◽

Vol 33 (15_suppl) ◽

pp. e19127-e19127

Author(s):

Jie Wang ◽

Qinxiang Guo ◽

Shuhang Wang ◽

Hua Bai ◽

Jianchun Duan

Keyword(s):

Growth Factor ◽

Programmed Cell Death ◽

Fibroblast Growth Factor ◽

Lung Carcinoma ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Stage Iii ◽

Fibroblast Growth ◽

Programmed Cell Death 1

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Abstract 5778: Fragment-based drug discovery of selective inhibitors of fibroblast growth factor receptor (FGFr)

10.1158/1538-7445.am10-5778 ◽

2010 ◽

Author(s):

Gordon Saxty ◽

M S. Squires ◽

C W. Murray ◽

V Berdini ◽

G A. Ward ◽

...

Keyword(s):

Drug Discovery ◽

Growth Factor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors ◽

Fragment Based Drug Discovery

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Fibroblast growth factor receptor 1 gene amplification and protein expression in human lung cancer

Cancer Medicine ◽

10.1002/cam4.2994 ◽

2020 ◽

Vol 9 (10) ◽

pp. 3574-3583 ◽

Author(s):

Omar Elakad ◽

Anna‐Maria Lois ◽

Katja Schmitz ◽

Sha Yao ◽

Sara Hugo ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Protein Expression ◽

Fibroblast Growth Factor ◽

Gene Amplification ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Human Lung Cancer ◽

Fibroblast Growth

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Fibroblast Growth Factor Receptor 4 (FGFR4) Selective Inhibitors as Hepatocellular Carcinoma Therapy: Advances and Prospects

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b01531 ◽

2018 ◽

Vol 62 (6) ◽

pp. 2905-2915 ◽

Author(s):

Xiaoyun Lu ◽

Hao Chen ◽

Adam V. Patterson ◽

Jeff B. Smaill ◽

Ke Ding

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors

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ChemInform Abstract: 1-Oxo-3-aryl-1H-indene-2-carboxylic Acid Derivatives as Selective Inhibitors of Fibroblast Growth Factor Receptor-1 Tyrosine Kinase.

10.1002/chin.199810112 ◽

2010 ◽

Vol 29 (10) ◽

pp. no-no

Author(s):

M. R. BARVIAN ◽

R. L. PANEK ◽

G. H. LU ◽

A. J. KRAKER ◽

A. AMAR ◽

...

Keyword(s):

Growth Factor ◽

Carboxylic Acid ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors

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1-Oxo-3-aryl-1H-indene-2-carboxylic acid derivatives as selective inhibitors of fibroblast growth factor receptor-1 tyrosine kinase

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(97)10110-x ◽

1997 ◽

Vol 7 (22) ◽

pp. 2903-2908 ◽

Author(s):

M.R. Barvian ◽

R.L. Panek ◽

G.H. Lu ◽

A.J. Kraker ◽

A. Amar ◽

...

Keyword(s):

Growth Factor ◽

Carboxylic Acid ◽

Tyrosine Kinase ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors

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220 Discovery of selective inhibitors of fibroblast growth factor receptor (FGFR): Antitumor activity in cellular and xenograft tumor models with FGFR activation

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(10)71925-x ◽

2010 ◽

Vol 8 (7) ◽

pp. 72

Author(s):

D. Markby ◽

M. Williams ◽

J. Li ◽

A. Plonowski ◽

S. Wu ◽

...

Keyword(s):

Growth Factor ◽

Antitumor Activity ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Xenograft Tumor ◽

Selective Inhibitors ◽

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Abstract 1361: Fragment based drug discovery of selective inhibitors of Fibroblast Growth Factor Receptor (FGFR)

10.1158/1538-7445.am2011-1361 ◽

2011 ◽

Author(s):

Gordon Saxty ◽

R Akkari ◽

P Angibaud ◽

J Arts ◽

P Benderitter ◽

...

Keyword(s):

Drug Discovery ◽

Growth Factor ◽

Fibroblast Growth Factor ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Selective Inhibitors ◽

Fragment Based Drug Discovery

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Combination effects of arsenic trioxide and fibroblast growth factor receptor inhibitor in squamous cell lung carcinoma

Lung Cancer ◽

10.1016/j.lungcan.2016.10.001 ◽

2016 ◽

Vol 101 ◽

pp. 111-119 ◽

Author(s):

Sze-Kwan Lam ◽

Leanne Lee Leung ◽

Yuan-Yuan Li ◽

Chun-Yan Zheng ◽

James Chung-Man Ho

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Arsenic Trioxide ◽

Lung Carcinoma ◽

Fibroblast Growth Factor Receptor ◽

Growth Factor Receptor ◽

Fibroblast Growth ◽

Squamous Cell Lung Carcinoma ◽

Cell Lung Carcinoma ◽

Receptor Inhibitor

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