scholarly journals Fatty acids from Clerodendrum volubile leaves induces cell cycle arrest, inhibits MMP‐9 expression, and modulates redox status in human breast cancer cell lines (616.2)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Ochuko Erukainure ◽  
Iqbal Choudhary ◽  
Osaretin Ebuehi ◽  
Asma Naqvi ◽  
Nadia Chaudhry ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Fatty Acids ◽  
Cell Cycle Arrest ◽  
Human Breast Cancer ◽  
Redox Status ◽  
Human Breast Cancer Cell ◽  
Breast Cancer Cell Lines ◽  
Human Breast ◽  
Cycle Arrest

Echinacea Angustifolia DC Extract Induces Apoptosis and Cell Cycle Arrest and Synergizes with Paclitaxel in the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines

2020 ◽  
pp. 1-19
Author(s):  
Daniel Abraham Espinosa-Paredes ◽  
Jorge Cornejo-Garrido ◽  
Mario Adán Moreno-Eutimio ◽  
Oswaldo Pablo Martínez-Rodríguez ◽  
María Eugenia Jaramillo-Flores ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Human Breast Cancer ◽  
Human Breast Cancer Cell ◽  
Breast Cancer Cell Lines ◽  
Human Breast ◽  
Echinacea Angustifolia ◽  
Cycle Arrest ◽  
Mcf 7

scholarly journals Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell

2002 ◽  
Vol 102 (3) ◽  
pp. 250-253 ◽  
Author(s):  
Hongbo Hu ◽  
Nam-Shik Ahn ◽  
Xinlin Yang ◽  
Yong-Soon Lee ◽  
Kyung-Sun Kang
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Breast Cancer Cell ◽  
Ganoderma Lucidum ◽  
Human Breast Cancer ◽  
Human Breast Cancer Cell ◽  
Human Breast ◽  
Cycle Arrest ◽  
Mcf 7

Molecular Mechanisms of Thymoquinone as Anticancer agent

2020 ◽  
Vol 23 ◽  
Author(s):  
Fatma Ismail Alhmied ◽  
Ali Hassan Alammar ◽  
Bayan Mohammed Alsultan ◽  
Marooj Alshehri ◽  
Faheem Hyder Pottoo
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Human Breast Cancer ◽  
Phase Cell ◽  
Cycle Phase ◽  
Human Breast ◽  
Cycle Arrest ◽  
Phase Arrest ◽  
Anti Cancer

Abstract:: Thymoquinone (TQ), the bioactive constituent of Nigella Sativa seeds is a well-known natural compound for the management of several types of cancers. The anti-cancer properties of thymoquinone are thought to be operated via intervening with various oncogenic pathways including cell cycle arrest, prevention of inflammation and oxidative stress, induction of invasion, metastasis, inhibition of angiogenesis, and apoptosis. As well as up-regulation and down-regulation of specific tumor suppressor genes and tumor promoting genes, respectively. Proliferation of various tumor cells is inhibited by TQ via induction of cell cycle arrest, disruption of the microtubule organization, and down regulating cell survival protein expression. TQ induces G1 phase cell cycle arrest in human breast cancer, colon cancer and osteosarcoma cells through inhibiting the activation of cyclin E or cyclin D and up-regulating p27and p21 a cyclin dependent kinase (Cdk) inhibitor. TQ concentration is a significant factor in targeting a particular cell cycle phase. While high concentration of TQ induced G2 phase arrest in human breast cancer (MCF-7) cells, low concentration causes S phase arrest. This review article provides mechanistic insights into the anti-cancer properties of thymoquinone.

Sign in / Sign up

Export Citation Format

Share Document