DIGITAL CUTANEOUS BLOOD FLOW, CARDIAC OUTPUT, BLOOD PRESSURE AND PULSE RATE IMMEDIATELY FOLLOWING THE ADMINISTRATION OF FOUR POTENTIAL VASODILATORS*

1951 ◽  
Vol 221 (6) ◽  
pp. 667-668 ◽  
Author(s):  
Ann Sayen ◽  
Orville Horwitz ◽  
Morris W. Stroud
1963 ◽  
Vol 204 (2) ◽  
pp. 301-303 ◽  
Author(s):  
L. Takács ◽  
V. Vajda

The effects of intraperitoneal and intravenous administration of serotonin on cardiac output, blood pressure, and organ distribution of blood flow (Rb86) were studied in the rat. Fifteen to thirty minutes after intraperitoneal injection (10 mg/kg) cardiac output was unchanged, while blood pressure was significantly reduced. Increase in blood flow was noted in the myocardium, pulmonary parenchyma and "carcass" (skeletal muscle, bone, CNS), with decrease in the kidney and the skin. Splanchnic blood flow was unchanged. Conversely, intravenous infusion of serotonin produced an increase of cardiac output, blood pressure, and cutaneous blood flow.


1983 ◽  
Vol 17 (4) ◽  
pp. 321-323 ◽  
Author(s):  
H. Minasian ◽  
D. Minassian

To determine the relationship between mammary and cutaneous blood flow (BF) the regional distribution of 86RbCl was used to estimate the fractional distribution of the cardiac output to these tissues in virgin, multiparous, pregnant and lactating mice. The results indicate a positive linear correlation between the values obtained for the skin and that obtained for its underlying mammary tissue. This finding may have a practical application, since the skin is more readily accessible for BF measurements than the mammary tissue that it covers.


1999 ◽  
Vol 86 (3) ◽  
pp. 799-805 ◽  
Author(s):  
Ricardo G. Fritzsche ◽  
Thomas W. Switzer ◽  
Bradley J. Hodgkinson ◽  
Edward F. Coyle

This study determined whether the decline in stroke volume (SV) during prolonged exercise is related to an increase in heart rate (HR) and/or an increase in cutaneous blood flow (CBF). Seven active men cycled for 60 min at ∼57% peak O2 uptake in a neutral environment (i.e., 27°C, <40% relative humidity). They received a placebo control (CON) or a small oral dose (i.e., ∼7 mg) of the β1-adrenoceptor blocker atenolol (BB) at the onset of exercise. At 15 min, HR and SV were similar during CON and BB. From 15 to 55 min during CON, a 13% decline in SV was associated with an 11% increase in HR and not with an increase in CBF. CBF increased mainly from 5 to 15 min and remained stable from 20 to 60 min of exercise in both treatments. However, from 15 to 55 min during BB, when the increase in HR was prevented by atenolol, the decline in SV was also prevented, despite a normal CBF response (i.e., similar to CON). Cardiac output was similar in both treatments and stable throughout the exercise bouts. We conclude that during prolonged exercise in a neutral environment the decline in SV is related to the increase in HR and is not affected by CBF.


2015 ◽  
Vol 30 (12) ◽  
pp. 2075-2079 ◽  
Author(s):  
Philip Andreas Schytz ◽  
Maria Lerche Mace ◽  
Anne Merete Boas Soja ◽  
Brian Nilsson ◽  
Nikolaos Karamperis ◽  
...  

1997 ◽  
Vol 59 (2) ◽  
pp. 255-256
Author(s):  
Yuka NAKAMURA ◽  
Shinichi WATANABE ◽  
Hisashi TAKAHASHI ◽  
Atsuhiko HASEGAWA

Author(s):  
Hans T. Versmold

Systemic blood pressure (BP) is the product of cardiac output and total peripheral resistance. Cardiac output is controlled by the heart rate, myocardial contractility, preload, and afterload. Vascular resistance (vascular hindrance × viscosity) is under local autoregulation and general neurohumoral control through sympathetic adrenergic innervation and circulating catecholamines. Sympathetic innovation predominates in organs receivingflowin excess of their metabolic demands (skin, splanchnic organs, kidney), while innervation is poor and autoregulation predominates in the brain and heart. The distribution of blood flow depends on the relative resistances of the organ circulations. During stress (hypoxia, low cardiac output), a raise in adrenergic tone and in circulating catecholamines leads to preferential vasoconstriction in highly innervated organs, so that blood flow is directed to the brain and heart. Catecholamines also control the levels of the vasoconstrictors renin, angiotensin II, and vasopressin. These general principles also apply to the neonate.


1979 ◽  
Vol 46 (2) ◽  
pp. 288-292 ◽  
Author(s):  
Y. A. Mengesha ◽  
G. H. Bell

Ten to fifteen healthy subjects, ages 18--30 yr, were used to assess the correlation of forearm blood flow with graded passive body tilts and vascular resistance and also to discern the relative effects of body tilts on finger blood flow. In the head-up tilts forearm blood flow and arterial blood pressure fell progressively, whereas forearm vascular resistance and pulse rate increased. In the head-down tilts the forearm blood flow and the arterial blood pressure increased, whereas the forearm vascular resistance and pulse rate decreased. These changes were found to be significantly correlated with the different tilt angles and with one another. In a preliminary study it was found that infrared heating of the carpometacarpal region produced finger vasodilatation similar to the forearm vasodilatation observed by Crockford and Hellon (6). However, unlike forearm blood flow, finger blood flow showed no appreciable response to either the head-up or head-down tilts. This indicates that the sympathetic tone and the volume of blood in the finger are not appreciably altered by this test procedure at least 1 min after the body tilt is assumed.


1963 ◽  
Vol 18 (4) ◽  
pp. 781-785 ◽  
Author(s):  
Leo C. Senay ◽  
Leon D. Prokop ◽  
Leslie Cronau ◽  
Alrick B. Hertzman

The relationship of local skin temperature and the onset of sweating to the local cutaneous blood flow was studied in the forearm and calf. The purpose of the investigation was to appraise the possible relation of sweat gland activity to the cutaneous vasodilatation which has been attributed to bradykinin or to intracranial temperatures. The onset of sweating was not marked by any apparently related increases in the rate of cutaneous blood flow. On the contrary, the onset of sweating was followed often by a stabilization or even a decrease in the level of cutaneous blood flow. The relations of the latter to the local skin temperature were complex, particularly in the forearm. There appeared to be additional unidentified influences, possibly vasomotor, operating on the skin vessels during transitional phases in the relation of skin temperature to blood flow. Submitted on October 15, 1962


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