Pharmacodynamics of Rocuronium and Succinylcholine and Their Effects on Blood Pressure, Heart Rate, and Intraocular Pressure

1994 ◽  
Vol 81 (SUPPLEMENT) ◽  
pp. A1072
Author(s):  
E. N. Robertson ◽  
J. M. Hull ◽  
L. E. H. Vanlinthout ◽  
L. H. D. J. Booij
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure

scholarly journals Effects of Preoperative Intravenous Clonidine in Patients Undergoing Cataract Surgery: A Double-Blind, Randomized Trial

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ana Ellen Queiroz Santiago ◽  
Adriana Machado Issy ◽  
Rioko Kimiko Sakata
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure ◽  
Myocardial Ischemia ◽  
Cataract Surgery ◽  
The Other ◽  
Intraocular Lens Implantation ◽  
Double Blind ◽  
Lens Implantation ◽  
Lidocaine Gel

Objectives. The aim of this study was to assess the effects of clonidine on intraoperative analgesia, sedation, intraocular and blood pressure, arrhythmia, and ischemia.Methods. Forty patients undergoing cataract surgery were allocated into two groups. They were monitored with Holter machine, the pupil was dilated, and 30 minutes later, 20 patients received clonidine (4 µg/kg), while the other 20 patients were given a 0.9% saline intravenously. Twenty minutes later, 2% lidocaine gel was applied. There were assessed intraoperative analgesia, intraocular pressure, blood pressure, heart rate, and the occurrence of arrhythmias and myocardial ischemia.Results. Pain intensity was lower in G1 during the phacoemulsification, irrigation, aspiration, and intraocular lens implantation. The HR and BP were lower with clonidine. The IOP was lower with clonidine after 15 minutes and at the end of the surgery. Sedation was higher with clonidine. The incidence of arrhythmia was lower at the end of surgery with clonidine. The incidence of myocardial ischemia did not differ between the groups.Conclusions. Clonidine (4 µg/kg) before a phacoemulsification reduced the intensity of pain during cataract surgery. It also induced sedation, reduction of BP, HR, and incidence of arrhythmia at the end of the surgery, and did not alter myocardial ischemia. This trial is registered with Clinicaltrials.govNCT01677351.

Effects of a Sustained Muscular Contraction on Human Intraocular Pressure

1974 ◽  
Vol 47 (3) ◽  
pp. 249-257 ◽  
Author(s):  
D. F. Marcus ◽  
H. F. Edelhauser ◽  
M. G. Maksud ◽  
R. L. Wiley
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure ◽  
Recovery Period ◽  
Maximum Voluntary Contraction ◽  
Isometric Exercise ◽  
Lactate Concentration ◽  
Post Exercise ◽  
Blood Samples ◽  
Hand Grip

1. Normal subjects performed fatiguing static hand-grip contraction at tensions of 20% and 55% of their maximum voluntary contraction (MVC). Intraocular pressure (IOP) was measured by applanation tonometry before, during and after the isometric exercise. Forearm blood samples were taken from the antecubital vein in both the exercised and non-exercised arm before and 2 min post-exercise for measurement of plasma lactate, osmolality, Pv,o2, Pv,co2 and pH. 2. During hand grip the heart rate and blood pressure increased significantly, whereas the IOP remained unchanged from control in both the 20% and 55% MVC experiments. 3. In the recovery period heart rate and blood pressure returned to control values within 3 min and the IOP decreased significantly from control in both the 20% and 55% MVC experiments. 4. When an occlusion cuff was inflated on the exercising arm just before release of the 55% MVC grip, the decreased IOP could be delayed until the cuff was released. 5. Post-exercise blood samples showed elevated lactate concentrations and Pv,o2 and decreased pH in the exercised arm; however, the values remained unchanged in the non-exercised arm. The decreased IOP after exercise may be related to an increased blood lactate concentration.

Correlating Intraocular Pressure, Blood Pressure, and Heart Rate Changes after Jogging

2004 ◽  
Vol 14 (2) ◽  
pp. 117-122 ◽  
Author(s):  
V.E. Karabatakis ◽  
K.I. Natsis ◽  
T.E. Chatzi balis ◽  
S.L. Lake ◽  
I.T. Bisbas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure

scholarly journals Home Monitoring in Glaucoma

2018 ◽  
Vol 12 (2) ◽  
pp. 102 ◽  
Author(s):  
Toby Boote ◽  
Andrew J Tatham ◽  
◽  
◽  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure ◽  
New Technologies ◽  
Home Monitoring ◽  
Self Monitoring ◽  
Digital Devices ◽  
Wide Range ◽  
Efficacy Of Treatment

A wide range of relatively cheap, wearable digital devices are now available that enable self-monitoring of parameters such as heart rate, blood pressure, physical activity and sleep patterns. Although these devices are often marketed at healthy people, new technologies that permit home monitoring may also have the potential to improve the detection and management of chronic diseases including glaucoma. If patients were able to measure their intraocular pressure or perform perimetry at home, many more measurements could be obtained, with the potential to improve our ability to differentiate true change from test–retest variability. Home monitoring may also improve our ability to determine efficacy of treatment and enhance patient engagement.

Comparison of Visual Function and Ocular Hemodynamics between Pre- and Post-Menopausal Women

2008 ◽  
Vol 18 (2) ◽  
pp. 320-323 ◽  
Author(s):  
B.A. Siesky ◽  
A. Harris ◽  
C. Patel ◽  
C.L. Klaas ◽  
M. Harris ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Flow ◽  
Intraocular Pressure ◽  
Contrast Sensitivity ◽  
Premenopausal Women ◽  
Menopausal Women ◽  
Post Menopausal ◽  
The Right ◽  
Ocular Hemodynamics

Purpose The incidence of eye disease increases with age and can often be linked to worsening cardiovascular function and increasing intraocular pressure. Estrogen is known to have vasodilatory effects in the systemic circulation. Decreased estrogen levels during menopause may therefore complicate or contribute to ocular pathologies as estrogen receptors are found in both retinal and choroidal tissue. The purpose of this investigation was to determine the effects of menopause on visual function and cardiovascular and ocular hemodynamics. Methods Twelve premenopausal and 24 postmenopausal women were evaluated at the Indiana University School of Medicine during a single study visit. Vision screening and ocular blood flow evaluations were performed, including blood pressure, heart rate, visual acuity, contrast sensitivity, intraocular pressure, and retinal capillary and retrobulbar blood flow imaging. Vision and ocular hemodynamics were compared using unpaired Student t-tests with pp<0.05 regarded as statistically significant. Results The premenopausal group had significantly lower heart rate (-16.1 b/m, p=0.0001) and systolic blood pressure (-17.7 mmHg, p=0.003) than postmenopausal subjects. Contrast sensitivity was significantly higher (measured in log units) in premenopausal women in both the right (0.25, p=0.039; 0.16, p=0.039) and left (0.45, p=0.001; 0.27, p=0.032) eyes at 9 and 18 cycles per degree, respectively. Premenopausal women also had significantly lower intraocular pressure in both the right (-2.19 mmHg, p=0.024) and left (-1.74 mmHg, p=0.035) eyes. Total ocular perfusion was not significantly different between groups. Conclusions This pilot work suggests that postmenopausal women have lower contrast sensitivity detection and elevated intraocular pressures compared to premenopausal women. Premenopausal women have lower cardiovascular risk factors, while total ocular circulation was similar to post-menopausal women.

scholarly journals COMPARISON OF INTRAOCULAR PRESSURE AND HAEMODYNAMIC RESPONSES TO INSERTION OF THE I - GEL AND ENDOTRACHEAL TUBE IN ELECTIVE OPHTHALMOLOGICAL SURGERIES

2021 ◽  
Vol 71 (3) ◽  
pp. 1046-50
Author(s):  
Sana Abbas ◽  
Aisha Rafique ◽  
Dr Dilshad ◽  
Beenish Abbas
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure ◽  
General Anesthesia ◽  
Endotracheal Tube ◽  
Armed Forces ◽  
Airway Device ◽  
P Value ◽  
Group A ◽  
Age Range

Objective: To compare I–Gel versus endotracheal tube effects on hemodynamic stability and intraocular pressure in patients undergoing elective ophthalmological surgeries. Study Design: Quasi-experimental study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi Pakistan, from Nov 2019 to Oct 2020. Methodology: A total of 108 patients undergoing elective ophthalmological surgeries under general anesthesia from both genders, age range between 18-45 years, American Society of Anesthesiologists status I or II were included. General anesthesia given following standard procedures and monitoring. Heart rate, Systolic & Diastolic blood pressure monitored and intraocular pressure measured in each eye with Reichert ton open at baseline, upon insertion of airway device and 5 minutes after insertion. Results: Total 108 patients enrolled in the study with a mean age of 37.74 ± 6.0 years and age-range of 18-45. Heart rate at Insertion in I-Gel group was 78.14 ± 3.41 beats per minute whereas in intubated group was 97.20 ± 2.84 beats per minute, mean systolic blood pressure at insertion in group A and B was 115.28 ± 5.3 and 130.44 ± 2.81mm of Hg respectively. Intraocular pressure at insertion right eye in group A and B was 12.04 ± 0.48 and 17.98 ± 0.42 mm of Hg respectively. Intraocular pressure at insertion left eye in group A was 12.12 ± 0.45 whereas in group B was 17.95 ± 0.38mm of Hg (p-value=0.001). Conclusion: I–Gel provides better hemodynamic profile and intraocular pressure stability when compared with endotracheal tube.

scholarly journals Effects of pneumoperitoneum and trendelenburg position on intraocular pressure (IOP) in isofluorane anesthetised cats

2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Arilton Teodoro De Souza ◽  
Débora De Oliveira Garcia ◽  
Lilian Toshiko Nishimura ◽  
Marcos Lúcio Magalhães ◽  
Ewaldo De Mattos-junior ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Blood Pressure ◽  
Heart Rate ◽  
Intraocular Pressure ◽  
Partial Pressure ◽  
Respiratory Rate ◽  
Mean Arterial Blood Pressure ◽  
Trendelenburg Position ◽  
Arterial Blood ◽  
Ocular Pressure

The aim of this study was to determine whether a pneumoperitoneum of 10 mmHg combined or not with the Trendelenburg position could lead to significant changes in intraocular pressure (IOP), ocular pressure perfusion (OPP), and cardiorespiratory variables; as well as determine whether a correlation exists between IOP and mean arterial blood pressure (MAP), and/or partial pressure of carbon dioxide in arterial blood (PaCO2) in cats. Animals were allocated in two groups (n=7/group): GC (without inclination) and GTREN (Trendelenburg position). The variables were recorded before (baseline) and during 30 minutes (T5-T30) after insufflation. In GTREN, a reduction in heart rate was observed at T5 and in respiratory rate at T5 and T15. There was an increase in IOP at T5-T30 in comparison to baseline. There was a reduction in potential of hydrogen in arterial blood in both groups at all times in comparison to baseline. Partial pressure of carbon dioxide in arterial blood was increased at T15-T30 in GC and at T5-T30 in GTREN. In conclusion, the pneumoperitoneum of 10mmHg CO2 did not significantly affect IOP or OPP in cats anaesthetised with isofluorane and kept under spontaneous ventilation. However, induced pneumoperitoneum combined with Trendelenburg position resulted in an increase in IOP in cats subjected to the same anaesthetic conditions, but did not affect OPP.

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