SEVERE HEPATITIS DUE TO CO-INFECTION WITH HIV AND HEPATITIS C VIRUS IN A YOUNG INFANT

AIDS ◽  
1994 ◽  
Vol 8 (Supplement 4) ◽  
pp. S48
Author(s):  
C-A. Wyler ◽  
D. Belli ◽  
S. Suter ◽  
M. Schappi ◽  
P. Pilloux ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Young Infant ◽  
Severe Hepatitis

Increased Risk of Severe Hepatitis C Virus Recurrence After Liver Transplantation in Patients With a T Allele of IL28B rs12979860

2012 ◽  
Vol 94 (3) ◽  
pp. 275-280 ◽  
Author(s):  
Elisa Cisneros ◽  
Isolina Baños ◽  
María Jesús Citores ◽  
Ana Duca ◽  
Clara Salas ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Severe Hepatitis ◽  
Increased Risk

Hepatitis C virus genotypes and severe hepatitis C virus recurrence after liver transplantation

1997 ◽  
Vol 29 (1-2) ◽  
pp. 522-523 ◽  
Author(s):  
A.B. Alberti ◽  
L.S. Belli ◽  
E. Silini ◽  
C. Zavaglia ◽  
G. Iamoni ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Severe Hepatitis ◽  
Virus Genotypes ◽  
Hepatitis C Virus Genotypes

scholarly journals Heterologous T cell immunity in severe hepatitis C virus infection

2005 ◽  
Vol 201 (5) ◽  
pp. 675-680 ◽  
Author(s):  
Simona Urbani ◽  
Barbara Amadei ◽  
Paola Fisicaro ◽  
Massimo Pilli ◽  
Gabriele Missale ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
T Cell ◽  
Virus Infection ◽  
Cell Response ◽  
Cd8 T Cell ◽  
Cross Reactivity ◽  
T Cell Response ◽  
Hcv Infection ◽  
Severe Hepatitis

Hepatitis C virus (HCV) can cause liver disease of variable severity. Expansion of preexisting memory CD8 T cells by cross-reactivity with a new heterologous virus infection has been shown in mice to shape the repertoire of the primary response and to influence virus-related immunopathology (Selin, L.K. 2004. Immunity. 20:5–16). To determine whether this mechanism can influence the course of HCV infection, we analyzed the features of the HCV-specific CD8 T cell response in eight patients with acute HCV infection, two of whom had a particularly severe illness. Patients with severe hepatitis, but not those with mild disease, showed an extremely vigorous CD8 T cell response narrowly focused on a single epitope (NS3 1073–1081), which cross-reacted with an influenza neuraminidase sequence. Our results suggest that CD8 T cell cross-reactivity influences the severity of the HCV-associated liver pathology and depicts a model of disease induction that may apply to different viral infections.

scholarly journals The paradox of NKp46+natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment

Gut ◽  
2013 ◽  
Vol 63 (3) ◽  
pp. 515-524 ◽  
Author(s):  
Tom Pembroke ◽  
Adam Christian ◽  
Emma Jones ◽  
Robert K Hills ◽  
Eddie C Y Wang ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Interferon Α ◽  
Killer Cells ◽  
Severe Hepatitis

PegIFNα/ribavirin/protease inhibitor combination in severe hepatitis C virus-associated mixed cryoglobulinemia vasculitis

2015 ◽  
Vol 62 (1) ◽  
pp. 24-30 ◽  
Author(s):  
David Saadoun ◽  
Matthieu Resche Rigon ◽  
Stanislas Pol ◽  
Vincent Thibault ◽  
François Blanc ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protease Inhibitor ◽  
Mixed Cryoglobulinemia ◽  
Severe Hepatitis ◽  
Inhibitor Combination
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