SALIVARY ANTI-TRANSGLUTAMINASE AUTOANTIBODIES IN COELIAC DISEASE AT THE DIAGNOSIS AND DURING FOLLOW-UP

2005 ◽  
Vol 40 (5) ◽  
pp. 664-665
Author(s):  
R Nenna ◽  
C Tiberti ◽  
M Ferri ◽  
E Thanasi ◽  
S Mura ◽  
...  
Keyword(s):  
Coeliac Disease

scholarly journals Neurological Evaluation of Patients with Newly Diagnosed Coeliac Disease Presenting to Gastroenterologists: A 7-Year Follow-Up Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1846
Author(s):  
Marios Hadjivassiliou ◽  
Iain D. Croall ◽  
Richard A. Grünewald ◽  
Nick Trott ◽  
David S. Sanders ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Brain Imaging ◽  
Cerebellar Atrophy ◽  
Neurological Dysfunction ◽  
Close Monitoring ◽  
Newly Diagnosed ◽  
Positive Serology ◽  
Original Cohort ◽  
Follow Up Study

We have previously shown that 67% of patients with newly diagnosed coeliac disease (CD) presenting to gastroenterologists have evidence of neurological dysfunction. This manifested with headache and loss of co-ordination. Furthermore 60% of these patients had abnormal brain imaging. In this follow-up study, we re-examined and re-scanned 30 patients from the original cohort of 100, seven years later. There was significant reduction in the prevalence of headaches (47% to 20%) but an increase in the prevalence of incoordination (27% to 47%). Although those patients with coordination problems at baseline reported improvement on the gluten free diet (GFD), there were 7 patients reporting incoordination not present at baseline. All 7 patients had positive serology for one or more gluten-sensitivity related antibodies at follow-up. In total, 50% of the whole follow-up cohort were positive for one or more gluten-related antibodies. A comparison between the baseline and follow-up brain imaging showed a greater rate of cerebellar grey matter atrophy in the antibody positive group compared to the antibody negative group. Patients with CD who do not adhere to a strict GFD and are serological positive are at risk of developing ataxia, and have a significantly higher rate of cerebellar atrophy when compared to patients with negative serology. This highlights the importance of regular review and close monitoring.

scholarly journals Cancer incidence and factors associated with malignancies in coeliac disease during long‐term follow‐up

GastroHep ◽  
2021 ◽  
Vol 3 (2) ◽  
pp. 107-115
Author(s):  
Inka Koskinen ◽  
Kaisa Hervonen ◽  
Eero Pukkala ◽  
Timo Reunala ◽  
Katri Kaukinen ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Cancer Incidence ◽  
Factors Associated ◽  
Long Term Follow Up

Coeliac crisis mimicking nephrotic syndrome in a post-partum patient

2019 ◽  
Vol 64 (3) ◽  
pp. 116-118
Author(s):  
Özant Helvacı ◽  
Seyma Yıldız ◽  
Berfu Korucu ◽  
Ulver Derici ◽  
Turgay Arinsoy
Keyword(s):  
Nephrotic Syndrome ◽  
Coeliac Disease ◽  
Post Partum ◽  
Lower Extremity Weakness ◽  
Case Presentation ◽  
Multisystem Involvement ◽  
Life Threatening ◽  
History Of ◽  
Rare Occasion

Background Coeliac crisis is a life-threatening presentation of coeliac disease. Severe diarrhoea, weight loss, electrolyte imbalances and malnutrition are prominent features. Although mainly a disease of childhood, it can on the rare occasion be diagnosed in adults. Case presentation A 25-year-old female with severe generalised oedema, lower extremity weakness, hypokalemia and profound hypoalbuminemia was referred with an initial diagnosis of nephrotic syndrome. Three months previously she had given birth to a healthy child following an uneventful pregnancy. She did not have proteinuria. She had a history of diarrhoea with gluten-containing food since childhood but lacked a formal diagnosis of coeliac disease. A duodenal biopsy confirmed the suspected diagnosis. Coeliac crisis was diagnosed with life-threatening multisystem involvement. Introduction of a gluten-free diet abolished all disease symptoms and ameliorated laboratory parameters at six months’ follow-up. Conclusion Coeliac crisis is a rare, yet dangerous presentation of coeliac disease in adults. As this case suggests, it can present with generalised oedema and hypoalbuminemia mimicking nephrotic syndrome. Rapid diagnosis is the key to successful treatment.

P096 Children with “borderline” TTG values in a screening for Coeliac disease on school population: follow-up after two years

2018 ◽  
Vol 50 (4) ◽  
pp. e392-e393
Author(s):  
F. Anton ◽  
L. Balanzoni ◽  
M. Cinquetti ◽  
M.T. Trevisan ◽  
N. Scattolo ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
School Population

scholarly journals Long-term follow-up of coeliac disease - what do coeliac patients want?

2006 ◽  
Vol 23 (6) ◽  
pp. 827-831 ◽  
Author(s):  
J. R. BEBB ◽  
A. LAWSON ◽  
T. KNIGHT ◽  
R. G. LONG
Keyword(s):  
Coeliac Disease ◽  
Long Term Follow Up

scholarly journals Interventions to Increase Adherence to a Gluten Free Diet in Patients with Coeliac Disease: A Scoping Review

2020 ◽  
Vol 2 (3) ◽  
pp. 318-326
Author(s):  
Humayun Muhammad ◽  
Sue Reeves ◽  
Sauid Ishaq ◽  
Yvonne Jeanes
Keyword(s):  
Coeliac Disease ◽  
Intervention Studies ◽  
Gluten Free Diet ◽  
Online Course ◽  
Dietary Adherence ◽  
Inflammatory Disorder ◽  
Gluten Free ◽  
Robust Methods ◽  
Chronic Inflammatory Disorder

Coeliac disease is a chronic inflammatory disorder of the small bowel, characterised by permanent intolerance to gluten. The only current and effective treatment for coeliac disease is a gluten free diet [GFD], however this is challenging for patients to adhere to. The review aims to identify published interventions designed to improve patients’ adherence to a GFD. Ten intervention studies were identified and included within the review; whilst heterogeneous in delivery, all included an educational, behavioural, and practical element. Five interventions significantly improved dietary adherence, these included follow-up appointments, a telephone clinic, an online course, cooking sessions and psychological support. All studies were small and used varied methods to assess adherence. There is a paucity of well-designed interventions to promote dietary adherence, in future more robust methods for ascertaining adherence is needed, we recommend greater inclusion of dietetic assessment and combining more than one method for assessing adherence.

PWE-133 Follow-up management of coeliac disease – who, when, where and what?

2017 ◽  
Author(s):  
L Pritchard ◽  
JR Bebb ◽  
M Abdelrahim ◽  
C Waters ◽  
IA Murray ◽  
...  
Keyword(s):  
Coeliac Disease

scholarly journals Need for follow up in coeliac disease.

1994 ◽  
Vol 70 (3) ◽  
pp. 211-213 ◽  
Author(s):  
M T Bardella ◽  
N Molteni ◽  
L Prampolini ◽  
A M Giunta ◽  
A R Baldassarri ◽  
...  
Keyword(s):  
Coeliac Disease
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