Cellular Proliferative Fraction of Metastatic Lymph Nodes Predicts Survival in Stage D1 (TxN+MO) Prostate Cancer

1996 ◽  
pp. 1674-1677 ◽  
Author(s):  
Michael L. Cher ◽  
Robert A. Stephenson ◽  
Brent C. James ◽  
Peter R. Carroll
1993 ◽  
Vol 150 (2 Part 1) ◽  
pp. 400-406 ◽  
Author(s):  
Dies van den Ouden ◽  
Bernhard Tribukait ◽  
Jan H.M. Blom ◽  
Sophie D. Fossa ◽  
Karl H. Kurth ◽  
...  

1996 ◽  
Vol 155 (5) ◽  
pp. 1674-1677 ◽  
Author(s):  
Michael L. Cher ◽  
Robert A. Stephenson ◽  
Brent C. James ◽  
Peter R. Carroll

2019 ◽  
Vol 20 (7) ◽  
pp. 1721 ◽  
Author(s):  
Clément Morgat ◽  
Adrien Chastel ◽  
Vincent Molinie ◽  
Romain Schollhammer ◽  
Gaétan Macgrogan ◽  
...  

Neurotensin and its high-affinity receptor, NTR1, are involved in the growth of various tumors. Few data are available regarding NTR1 expression in normal and tumoral human prostate tissue samples. NTR1 expression was assessed using immunohistochemistry in 12 normal prostate tissues, 11 benign prostatic hyperplasia (BPH), 44 prostate cancers, and 15 related metastatic lymph nodes (one per patient, when available). NTR1-staining was negative in normal prostate and BPH samples. NTR1 was overexpressed in four out of 44 (9.1%) primary tumors. There was no clear association between NTR1 overexpression and age, PSA-values, Gleason score, pT-status, nodal-status, or margin. NTR1 was expressed at a high level of five out of 15 (33.3%) metastatic lymph nodes. NTR1 overexpression was thus more frequent in metastatic lymph nodes than in primary tumors (p = 0.038). In this limited series of samples, NTR1 overexpression was observed in few primary prostate cancers. Upregulation was more frequent in related lymph nodes. The presence of this target in metastatic lymph nodes may open new perspectives for imaging and radionuclide therapy of prostate cancer. Factors driving NTR1 expression in primary prostate cancer and in nodal and distant metastases still need to be characterized.


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2017 ◽  
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pp. 133-138 ◽  
Author(s):  
Leilei Xia ◽  
Ryan Zeh ◽  
Jack Mizelle ◽  
Andrew Newton ◽  
Jarrod Predina ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 144-145
Author(s):  
Philippe Gannon ◽  
Mona Alam Fahmy ◽  
Louis Bégin ◽  
Audrey Djoukhadjian ◽  
Abdelali Filali-Mouhim ◽  
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2015 ◽  
Vol 68 (3) ◽  
pp. 530-534 ◽  
Author(s):  
Tobias Maurer ◽  
Gregor Weirich ◽  
Margret Schottelius ◽  
Martina Weineisen ◽  
Benjamin Frisch ◽  
...  

2006 ◽  
Vol 55 (2) ◽  
pp. 183 ◽  
Author(s):  
Joo Hee Cha ◽  
Woo Kyung Moon ◽  
Jung Eun Cheon ◽  
Young Hwan Koh ◽  
Eun Hye Lee ◽  
...  

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