Intracranial pressure time course in primary intracerebral hemorrhage

Neurosurgery ◽  
1979 ◽  
Vol 4 (6) ◽  
pp. 504???11 ◽  
Author(s):  
I Papo ◽  
P Janny ◽  
G Caruselli ◽  
G Colnet ◽  
A Luongo
Keyword(s):  
Intracranial Pressure ◽  
Intracerebral Hemorrhage ◽  
Time Course ◽  
Pressure Time

Intracranial Pressure Time Course in Primary Intracerebral Hemorrhage

Neurosurgery ◽  
1979 ◽  
Vol 4 (6) ◽  
pp. 504-511 ◽  
Author(s):  
Isacco Papo ◽  
Pierre Janny ◽  
Giuseppe Caruselli ◽  
Gilles Colnet ◽  
Antonio Luongo
Keyword(s):  
Intracranial Pressure ◽  
Time Course ◽  
Elevated Pressure ◽  
Deep Coma ◽  
Postoperative Course ◽  
Disturbance Of Consciousness ◽  
Pressure Time ◽  
Intermediate Disturbances ◽  
Over Time ◽  
Definite Correlation

abstract The course of intracranial pressure (ICP) over time was studied in 66 hypertensive and/or atherosclerotic patients harboring intracerebral hematomas. Patients with no disturbance of consciousness showed normal or only slightly elevated pressure. Conversely, most patients in deep coma exhibited high pressure with a tendency to rise further no matter what treatment was used. In the remaining patients with intermediate disturbances of consciousness, no definite correlation was found between ICP, clinical condition, and outcome. In all of the patients who underwent operation, the postoperative course of ICP over time was also studied and seemed to depend to a certain extent on the timing of the operation.

scholarly journals C-reactive protein in intracerebral hemorrhage: Time course, tissue localization, and prognosis

Neurology ◽  
2012 ◽  
Vol 79 (7) ◽  
pp. 690-699 ◽  
Author(s):  
M. Di Napoli ◽  
D. A. Godoy ◽  
V. Campi ◽  
L. Masotti ◽  
C. J. Smith ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Time Course ◽  
C Reactive Protein ◽  
Tissue Localization ◽  
Reactive Protein

Evaluation of a method for noninvasive intracranial pressure assessment during infusion studies in patients with hydrocephalus

2000 ◽  
Vol 92 (5) ◽  
pp. 793-800 ◽  
Author(s):  
Bernhard Schmidt ◽  
Marek Czosnyka ◽  
Jens Jürgen Schwarze ◽  
Dirk Sander ◽  
Werner Gerstner ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Intracranial Pressure ◽  
Time Course ◽  
Cerebral Blood Flow Velocity ◽  
Absolute Error ◽  
Content Type ◽  
Arterial Blood ◽  
Potential Clinical Benefit ◽  
The Mean ◽  
Fine Print

Object. A mathematical model previously introduced by the authors allowed noninvasive intracranial pressure (nICP) assessment. In the present study the authors investigated this model as an aid in predicting the time course of raised ICP during infusion tests in patients with hydrocephalus and its suitability for estimating the resistance to outflow of cerebrospinal fluid (Rcsf).Methods. Twenty-one patients with hydrocephalus were studied. The nICP was calculated from the arterial blood pressure (ABP) waveform by using a linear signal transformation, which was dynamically modified by the relationship between ABP and cerebral blood flow velocity. This model was verified by comparison of nICP with “real” ICP measured during lumbar infusion tests. In all simulations, parallel increases in real ICP and nICP were evident. The simulated Rcsf was computed using nICP and then compared with Rcsf computed from real ICP. The mean absolute error between real and simulated Rcsf was 4.1 ± 2.2 mm Hg minute/ml. By the construction of simulations specific to different subtypes of hydrocephalus arising from various causes, the mean error decreased to 2.7 ± 1.7 mm Hg minute/ml, whereas the correlation between real and simulated Rcsf increased from R = 0.73 to R = 0.89 (p < 0.001).Conclusions. The validity of the mathematical model was confirmed in this study. The creation of type-specific simulations resulted in substantial improvements in the accuracy of ICP assessment. Improvement strategies could be important because of a potential clinical benefit from this method.

scholarly journals Sustained moderate reductions in arterial CO2 after brain trauma Time-course of cerebral blood flow velocity and intracranial pressure

2004 ◽  
Vol 30 (12) ◽  
pp. 2180-2187 ◽  
Author(s):  
Luzius A. Steiner ◽  
Marcella Balestreri ◽  
Andrew J. Johnston ◽  
Marek Czosnyka ◽  
Jonathan P. Coles ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Time Course ◽  
Cerebral Blood Flow Velocity ◽  
Brain Trauma

N-Terminal Pro-Brain Natriuretic Peptide Concentrations After Hypertensive Intracerebral Hemorrhage: Relationship With Hematoma Size, Hyponatremia, and Intracranial Pressure

2017 ◽  
Vol 33 (12) ◽  
pp. 663-670 ◽  
Author(s):  
Fei Li ◽  
Qian-Xue Chen ◽  
Shou-Gui Xiang ◽  
Shi-Zhun Yuan ◽  
Xi-Zhen Xu
Keyword(s):  
Intracranial Pressure ◽  
Intracerebral Hemorrhage ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Linear Regression Analysis ◽  
Peak Level ◽  
Hematoma Volume ◽  
The Mean ◽  
Hypertensive Intracerebral Hemorrhage ◽  
Mean Concentration

Introduction: The role of N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with hypertensive intracerebral hemorrhage (HICH) is poorly understood. This study aimed to investigate the secretion pattern of NT-proBNP in patients with HICH and to assess its relationship with hematoma size, hyponatremia, and intracranial pressure (ICP). Methods: This prospective study enrolled 147 isolated patients with HICH. Blood samples were obtained from each patient, and values of serum NT-proBNP, hematoma size, blood sodium, and ICP were collected for each patient. Results: The peak-to-mean concentration of NT-proBNP was 666.8 ± 355.1 pg/mL observed on day 4. The NT-proBNP levels in patients with hematoma volume >30 mL were significantly higher than those in patients with hematoma volume <30 mL ( P < .05). In patients with severe HICH, the mean concentration of NT-proBNP was statistically higher than that in patients with mild–moderate HICH ( P < .05), and the mean level of NT-proBNP in hyponatremia group was significantly higher than that in normonatremic group ( P < .05). In addition, the linear regression analysis indicated that serum NT-proBNP concentrations were positively correlated with ICP ( r = .703, P < .05) but negatively with blood sodium levels only in patients with severe HICH ( r = −.704, P < .05). The serum NT-proBNP levels on day 4 after admission were positively correlated with hematoma size ( r = .702, P < .05). Conclusion: The NT-proBNP concentrations were elevated progressively and markedly at least in the first 4 days after HICH and reached a peak level on the fourth day. The NT-proBNP levels on day 4 were positively correlated with hematoma size. There was a notable positive correlation between plasma NT-proBNP levels and ICP in patients with severe HICH. Furthermore, only in patients with severe HICH, the plasma NT-proBNP levels presented a significant correlation with hyponatremia, which did not occur in patients with mild–moderate HICH.

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