Ultrastructural changes in rat peripheral nerve following pneumatic tourniquet compressions

1984 ◽  
Vol 73 (2) ◽  
pp. 336
Author(s):  
Norman J. James
Keyword(s):  
Peripheral Nerve ◽  
Ultrastructural Changes ◽  
Pneumatic Tourniquet ◽  
Rat Peripheral Nerve

Ultrastructural changes in rat peripheral nerve following pneumatic tourniquet compression

1982 ◽  
Vol 57 (5) ◽  
pp. 660-666 ◽  
Author(s):  
Arthur J. Nitz ◽  
Daniel H. Matulionis
Keyword(s):  
Axonal Degeneration ◽  
Unit Area ◽  
Large Diameter ◽  
Male Rats ◽  
Ultrastructural Changes ◽  
Pneumatic Tourniquet ◽  
Content Type ◽  
Myelin Sheaths ◽  
Rat Peripheral Nerve ◽  
Fine Print

✓ The sciatic nerves of 12 male rats were examined in the electron microscope 14 days after pneumatic tourniquet compression. Tourniquet pressure was maintained at 300 mmHg for varied lengths of time (30 minutes to 3 hours). Nerves compressed for 30 minutes showed very mild fissuring of the myelin without axonal degeneration. Examination of nerves compressed for 1 to 3 hours showed progressively more varied and extensive damage. Changes included splaying of myelin lamellae, axonal shrinkage with periaxonal edema, Schwann cell hypertrophy, and an increase in the number of microtubules and mitochondria per unit area. The myelin sheaths of some fibers, compressed for more than 2 hours, were completely ruptured. These changes resemble nerve lesions which could be induced by a variety of experimental procedures. Ultrastructural changes produced by tourniquet compression are apparently time-related and affect large-diameter nerves more profoundly than smaller-diameter nerves. The data reported provide an explanation for delayed muscle rehabilitation experienced by patients who have undergone extremity surgery with pneumatic tourniquet application. The evidence presented suggests that the incidence of tourniquet palsy may be far greater than previously recognized.

scholarly journals Calpain II in rat peripheral nerve

1991 ◽  
Vol 564 (2) ◽  
pp. 328-331 ◽  
Author(s):  
Marina Mata ◽  
Nancy Kupina ◽  
David J. Fink
Keyword(s):  
Peripheral Nerve ◽  
Rat Peripheral Nerve ◽  
Calpain Ii

Neurohistochemical analysis of regeneration in rat peripheral nerve after end-to-side neurorrhaphy

2001 ◽  
Vol 6 (1) ◽  
pp. 82-87 ◽  
Author(s):  
Toru Yamauchi ◽  
Hiroshi Yajima ◽  
Susumu Tamai ◽  
Hajime Ohgushi ◽  
Makoto Tamai ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Rat Peripheral Nerve

Distribution of sodium channels during nerve elongation in rat peripheral nerve

2005 ◽  
Vol 10 (2) ◽  
pp. 214-220 ◽  
Author(s):  
Harumitsu Ichimura ◽  
Takashi Shiga ◽  
Ichiro Abe ◽  
Yuki Hara ◽  
Naoto Terui ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Sodium Channels ◽  
Rat Peripheral Nerve
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