Reduction of Proteinuria With Selective Vitamin D Receptor Activation Using Paricalcitol in Renal Transplant Patients.

Vitamin D has proven to be much more than a simple “calcium hormone.” The fact that the vitamin D receptor has been found in cells not related to mineral metabolism supports that statement. The interest of nephrologists in vitamin D and its effects beyond mineral metabolism has increased over the last few years, evidencing the importance of this so-called “sunshine hormone.” In the present review, we highlight the most recent developments in the traditional use of vitamin D in chronic kidney disease (CKD) patients, namely, the control of secondary hyperparathyroidism (sHPT). Furthermore, we also explore the data available regarding the new possible therapeutic uses of vitamin D for the treatment of other complications present in CKD patients, such as vascular calcification, left ventricular hypertrophy, or proteinuria. Finally, some still scarce but very promising data regarding a possible role of vitamin D in kidney transplant patients also are reviewed. The available data point to a potential beneficial effect of vitamin D in CKD patients beyond the control of mineral metabolism.

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MP723RELATION BETWEEN VITAMIN D LEVELS AND SYM TOMS OF DEPRESSION AND ANXIETY IN RENAL TRANSPLANT PATIENTS

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfw200.47 ◽

2016 ◽

Vol 31 (suppl_1) ◽

pp. i579-i579

Author(s):

Radmila Velickovic ◽

Jelena Lalic ◽

Tatjana Cvetkovic ◽

Goran Paunovic

Keyword(s):

Vitamin D ◽

Renal Transplant ◽

Depression And Anxiety ◽

Transplant Patients ◽

Vitamin D Levels ◽

Renal Transplant Patients

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Plasma 25-Hydroxy-Vitamin D in Normal Subjects and Patients with Terminal Renal Failure, on Maintenance Haemodialysis and after Transplantation

Clinical Science ◽

10.1042/cs0570473 ◽

1979 ◽

Vol 57 (5) ◽

pp. 473-476 ◽

Cited By ~ 9

Author(s):

J. B. Eastwood ◽

A. Daly ◽

G. D. Carter ◽

J. Alaghband-Zadeh ◽

H. E. De Wardener

Keyword(s):

Vitamin D ◽

Renal Failure ◽

Renal Transplant ◽

Normal Subjects ◽

Maintenance Haemodialysis ◽

Terminal Renal Failure ◽

Transplant Patients ◽

25 Hydroxy Vitamin D ◽

The Mean ◽

Renal Transplant Patients

1. Plasma 25-hydroxy-vitamin D concentration was measured in 40 normal subjects, 19 patients with terminal renal failure, 137 patients who had been on dialysis up to 11 years and in 17 renal transplant patients. 2. The mean plasma concentration of 25-hydroxy-vitamin D was below normal in patients with terminal renal failure and in patients who had been on maintenance haemodialysis for less than 1 year. The mean concentration in patients who had been on dialysis for more than 1 year and in renal transplant patients was normal. 3. The seasonal variation of plasma 25-hydroxy-vitamin D concentration found in the 58 patients on maintenance haemodialysis for more than 2 years is similar to that reported in normal subjects.

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