T-cell receptor usage in T lymphocyte clones specifically recognizing human melanoma

1993 ◽  
Vol 3 (1) ◽  
pp. 26
Author(s):  
M. Sensi ◽  
S. Salvi ◽  
C. Castelli ◽  
G. Nicolini ◽  
A. Anichini ◽  
...  
1994 ◽  
Vol 24 (8) ◽  
pp. 1929-1932 ◽  
Author(s):  
Helena Erlandsson ◽  
Åsa Müsseneru ◽  
Lars Klareskogu ◽  
Daniel P. Goldf

Immunity ◽  
2012 ◽  
Vol 37 (4) ◽  
pp. 611-621 ◽  
Author(s):  
Sophie E. Broughton ◽  
Jan Petersen ◽  
Alex Theodossis ◽  
Stephen W. Scally ◽  
Khai Lee Loh ◽  
...  

1999 ◽  
Vol 190 (9) ◽  
pp. 1257-1262 ◽  
Author(s):  
Chiyu Wang ◽  
Molly A. Bogue ◽  
Jonathan M. Levitt ◽  
David B. Roth

In SCID (severe combined immunodeficient) mice, proper assembly of immunoglobulin and T cell receptor (TCR) genes is blocked by defective V(D)J recombination so that B and T lymphocyte differentiation is arrested at an early precursor stage. Treating the mice with gamma irradiation rescues V(D)J rearrangement at multiple TCR loci, promotes limited thymocyte differentiation, and induces thymic lymphomas. These effects are not observed in the B cell lineage. Current models postulate that irradiation affects intrathymic T cell precursors. Surprisingly, we found that transfer of irradiated SCID bone marrow cells to unirradiated host animals rescues both TCR rearrangements and thymocyte differentiation. These data indicate that irradiation affects precursor cells at an earlier stage of differentiation than was previously thought and suggest new models for the mechanism of irradiation rescue.


1991 ◽  
Vol 21 (7) ◽  
pp. 1641-1647 ◽  
Author(s):  
Françoise Le Deist ◽  
Gabriela Thoenes ◽  
José Corado ◽  
Barbara Lisowska-Grospierre ◽  
Alain Fischer

AIDS ◽  
2002 ◽  
Vol 16 (11) ◽  
pp. 1459-1465 ◽  
Author(s):  
Thomas W. McCloskey ◽  
Viraga Haridas ◽  
Rajendra Pahwa ◽  
Savita Pahwa

2015 ◽  
Vol 110 (5) ◽  
pp. 596-605 ◽  
Author(s):  
Raquel Ferraz ◽  
Clarissa Ferreira Cunha ◽  
Maria Inês Pimentel ◽  
Marcelo Rosandiski Lyra ◽  
Armando Oliveira Schubach ◽  
...  

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