SOCIAL ISOLATION-INDUCED INCREASES IN FOOD HOARDING BEHAVIOUR ARE NOT CORRELATED WITH LOCOMOTOR ACTIVITY INTHEWISTAR RAT

1998 ◽  
Vol 9 (1) ◽  
pp. S94
Author(s):  
I. Weiss ◽  
J. Feldon ◽  
A. Domeney
Keyword(s):  
Locomotor Activity ◽  
Social Isolation ◽  
Food Hoarding

The Effect of Social Isolation on Locomotor Activity in the Houseflies (Musca Domestica)

2015 ◽  
Vol 28 (3) ◽  
pp. 288-296 ◽  
Author(s):  
Kayla McCarthy ◽  
Anders Kjærsgaard ◽  
Simon Bahrndorff ◽  
Toke Munk Schou ◽  
Tommaso Manenti ◽  
...  
Keyword(s):  
Locomotor Activity ◽  
Social Isolation ◽  
Musca Domestica

scholarly journals Voluntary locomotor activity mitigates oxidative damage associated with isolation stress in the prairie vole ( Microtus ochrogaster )

2015 ◽  
Vol 11 (7) ◽  
pp. 20150178 ◽  
Author(s):  
Kelsey L. Fletcher ◽  
Brittany N. Whitley ◽  
Lisa A. Treidel ◽  
David Thompson ◽  
Annie Williams ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Locomotor Activity ◽  
Social Isolation ◽  
Prairie Vole ◽  
Microtus Ochrogaster ◽  
Isolation Stress ◽  
Oxidative Balance ◽  
The Social ◽  
Social Animals ◽  
Physiological Systems

Organismal performance directly depends on an individual's ability to cope with a wide array of physiological challenges. For social animals, social isolation is a stressor that has been shown to increase oxidative stress. Another physiological challenge, routine locomotor activity, has been found to decrease oxidative stress levels. Because we currently do not have a good understanding of how diverse physiological systems like stress and locomotion interact to affect oxidative balance, we studied this interaction in the prairie vole ( Microtus ochrogaster ). Voles were either pair housed or isolated and within the isolation group, voles either had access to a moving wheel or a stationary wheel. We found that chronic periodic isolation caused increased levels of oxidative stress. However, within the vole group that was able to run voluntarily, longer durations of locomotor activity were associated with less oxidative stress. Our work suggests that individuals who demonstrate increased locomotor activity may be better able to cope with the social stressor of isolation.

Effect of neuropeptide Y antagonist BMS193885 on overeating and emotional responses induced by social isolation in rats

2021 ◽  
Vol 19 (2) ◽  
pp. 189-202
Author(s):  
Andrei A. Lebedev ◽  
Aleksandr R. Moskalev ◽  
Maksim E. Abrosimov ◽  
Eduard A. Vetlugin ◽  
Anna G. Pshenichnaya ◽  
...  
Keyword(s):  
Body Weight ◽  
Locomotor Activity ◽  
Social Isolation ◽  
Intranasal Administration ◽  
Depressive Disorders ◽  
Emotional Responses ◽  
The Body ◽  
Atypical Depression ◽  
Increased Risk ◽  
Metabolic Imbalance

BACKGROUND: Chronic stress of social isolation is associated with an increased risk of mental illness, such as atypical depression, and is usually accompanied by hyperphagia and weight gain. We have previously shown that the NPY antagonist Y1R BMS193885 reduces the conditioned place preference of ethanol. The involvement of NPY receptors in non-chemical forms of addiction is assumed. AIM: Was to analyze the effects of NPY Y1R BMS193885 on emotional responses and elements of bindge eating in rats caused by rearing in social isolation. MATERIALS AND METHODS: We used the tests open field, elevated plus maze, Porsolts forced swimming test, resident intruder test and method of conditioned eating test in well-fed rats. RESULTS: The level of depression, negative emotionality and locomotor activity increased in rats reared in isolation. After intranasal administration of BMS193885 high locomotor activity was maintained, but investigating activity increased in isolated rats. Isolated animals showed an increase in body weight at the 6th week of life. By to the 9th week, the body weight of the isolated rats was significantly higher than in animals reared in the community (р 0.05). Intranasal administration of 20 g BMS193885 for 1 week caused a decrease in feed intake in both groups of animals (р 0.05). Isolated rats began to consume the same amount of food as animals reared in the community after administration of 0.9% NaCl solution. At the same time, elements of bindge eating were observed in the study of the conditioned food test in satiated isolated rats, which did not appear after 1 week of intranasal administration of 20 g of BMS193885. CONCLUSIONS: The data obtained prove that rats reared in isolation can be considered as a potential model for binge eating, the basis for metabolic imbalance caused by individual housing in rodents. These considerations are of particular relevance when evaluating the effectiveness of drugs, diet, or other interventions for metabolic health and depressive disorders.

Subchronic MK-801 treatment and post-weaning social isolation in rats: Differential effects on locomotor activity and hippocampal long-term potentiation

2010 ◽  
Vol 212 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Donovan M. Ashby ◽  
Diala Habib ◽  
Hans C. Dringenberg ◽  
James N. Reynolds ◽  
Richard J. Beninger
Keyword(s):  
Locomotor Activity ◽  
Social Isolation ◽  
Long Term Potentiation ◽  
Mk 801 ◽  
Differential Effects ◽  
Term Potentiation
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