Pulmonary Function Tests, Respiratory Muscle Strength, and Endurance of Persons With Obesity

Abstract Objective: This study investigated the influence of Coronavirus Disease 2019 (COVID-19) on lung function in early convalescence phase. Methods: A prospective study of COVID-19 patients at the Fifth Affiliated Hospital of Sun Yat-sen University were conducted, with serial assessments including lung volumes (TLC), spirometry (FVC, FEV1), lung diffusing capacity for carbon monoxide (DLCO),respiratory muscle strength, 6-minute walking distance (6MWD) and high resolution CT being collected at 30 days after discharged. Results: 57 patients completed the serial assessments. There were 40 non-severe cases and 17 severe cases. Thirty-one patients (54.3%) had abnormal CT findings. Abnormalities were detected in the pulmonary function tests in 43 (75.4%) of the patients. Six (10.5%), 5(8.7%), 25(43.8%) 7(12.3%), and 30 (52.6%) patients had FVC, FEV1, FEV1/FVC ratio, TLC, and DLCO values less than 80% of predicted values, respectively. 28 (49.1%) and 13 (22.8%) patients had PImax and PEmax values less than 80% of the corresponding predicted values. Compared with non-severe cases, severe patients showed higher incidence of DLCO impairment (75.6%vs42.5%, p=0.019), higher lung total severity score（TSS）and R20, and significantly lower percentage of predicted TLC and 6MWD. No significant correlation between TSS and pulmonary function parameters was found during follow-up visit. Conclusion: Declining DLCO, lower respiratory muscle strength, and lung imaging abnormalities were detected in more than half of the COVID-19 patients in early convalescence phase. Compared with non-severe cases, severe patients had a higher incidence of DLCO impairment and encountered more TLC decrease and 6MWD decline.

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Impact of Coronavirus Disease 2019 on Pulmonary Function in Early Convalescence Phase

10.21203/rs.3.rs-26415/v2 ◽

2020 ◽

Author(s):

Yiying Huang ◽

Cui yan Tan ◽

Jian Wu ◽

Mei zhu Chen ◽

Zhen guo Wang ◽

...

Keyword(s):

Muscle Strength ◽

Pulmonary Function ◽

Respiratory Muscle ◽

Pulmonary Function Tests ◽

Walking Distance ◽

Lower Percentage ◽

Respiratory Muscle Strength ◽

Predicted Values ◽

Serial Assessments ◽

Convalescence Phase

Abstract Objective: This study investigated the influence of Coronavirus Disease 2019 (COVID-19) on lung function in early convalescence phase.Methods: A prospective retrospective study of COVID-19 patients at the Fifth Affiliated Hospital of Sun Yat-sen University were conducted, with serial assessments including lung volumes (TLC), spirometry (FVC, FEV1), lung diffusing capacity for carbon monoxide (DLCO),respiratory muscle strength, 6-minute walking distance (6MWD) and high resolution CT being collected at 30 days after discharged.Results: 57 patients completed the serial assessments. There were 40 non-severe cases and 17 severe cases. Thirty-one patients (54.3%) had abnormal CT findings. Abnormalities were detected in the pulmonary function tests in 43 (75.4%) of the patients. Six (10.5%), 5(8.7%), 25(43.8%) 7(12.3%), and 30 (52.6%) patients had FVC, FEV1, FEV1/FVC ratio, TLC, and DLCO values less than 80% of predicted values, respectively. 28 (49.1%) and 13 (22.8%) patients had PImax and PEmax values less than 80% of the corresponding predicted values. Compared with non-severe cases, severe patients showed higher incidence of DLCO impairment (75.6%vs42.5%, p=0.019), higher lung total severity score（TSS）and R20, and significantly lower percentage of predicted TLC and 6MWD. No significant correlation between TSS and pulmonary function parameters was found during follow-up visit.Conclusion: Impaired diffusing-capacityDeclining DLCO, lower respiratory muscle strength, and lung imaging abnormalities were detected in more than half of the COVID-19 patients in early convalescence phase. Compared with non-severe cases, severe patients had a higher incidence of DLCO impairment and encountered more TLC decrease and 6MWD decline.

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Effects of transcutaneous electrical nerve stimulation on pain, pulmonary function, and respiratory muscle strength in the postoperative period of thoracic surgery in an intensive care unit

Journal of Critical Care ◽

10.1016/j.jcrc.2017.09.141 ◽

2017 ◽

Vol 42 ◽

pp. 414

Author(s):

Hermann Heinrich Husch ◽

Pauline Lopes Carvalho ◽

Camila da Cunha Niedermeyer ◽

Adriana Kessler ◽

Graciele Sbruzzi

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Muscle Strength ◽

Thoracic Surgery ◽

Pulmonary Function ◽

Postoperative Period ◽

Transcutaneous Electrical Nerve Stimulation ◽

Respiratory Muscle ◽

Respiratory Muscle Strength ◽

Electrical Nerve Stimulation

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Monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of pulmonary function evaluation in amyotrophic lateral sclerosis

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2013000300004 ◽

2013 ◽

Vol 71 (3) ◽

pp. 146-152 ◽

Cited By ~ 6

Author(s):

Guilherme Fregonezi ◽

Palomma Russelly Saldanha Araújo ◽

Tathiana Lindemberg Ferreira Macêdo ◽

Mario Emilio Dourado Junior ◽

Vanessa Regiane Resqueti ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Muscle Strength ◽

Early Diagnosis ◽

Pulmonary Function ◽

Healthy Subjects ◽

Respiratory Muscle ◽

Function Evaluation ◽

Respiratory Muscle Strength ◽

Respiratory Dysfunction ◽

Lateral Sclerosis

ObjectiveIt was study the relationship between respiratory muscle strength and forced vital capacity (FVC) in patients with amyotrophic lateral sclerosis (ALS) versus healthy subjects.MethodsPulmonary function and respiratory muscle strength [maximal inspiratory (PImax), maximal expiratory (PEmax) and sniff nasal inspiratory pressure (SNIP)] were assessed in patients with ALS and healthy subjects, matched using cutoffs established in the literature for impaired pulmonary function and respiratory muscle weakness.ResultsTwenty-eight ALS patients and 28 healthy subjects were studied. We found sensitivity and specificity for PImax, PEmax and SNIP of 75/58%, 81/67% and 75/67%. The Receiver Operating Characteristic curve (ROC curve) indicated that the variables PImax, PEmax and SNIP can identify differences in respiratory muscle strength between ALS and healthy individuals at 0.89, 0.9 and 0.82, respectively. A positive correlation was recorded between FVC (%) versus SNIP, PImax and PEmax.ConclusionIn ALS, monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of FVC.

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Influence of a Six-Week Swimming Training with Added Respiratory Dead Space on Respiratory Muscle Strength and Pulmonary Function in Recreational Swimmers

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17165743 ◽

2020 ◽

Vol 17 (16) ◽

pp. 5743 ◽

Cited By ~ 1

Author(s):

Stefan Szczepan ◽

Natalia Danek ◽

Kamil Michalik ◽

Zofia Wróblewska ◽

Krystyna Zatoń

Keyword(s):

Muscle Strength ◽

Pulmonary Function ◽

Dead Space ◽

Respiratory Muscle ◽

Moderate Intensity ◽

Respiratory Muscle Strength ◽

Swimming Training ◽

Respiratory Muscle Fatigue ◽

Front Crawl ◽

Respiratory Dead Space

The avoidance of respiratory muscle fatigue and its repercussions may play an important role in swimmers’ health and physical performance. Thus, the aim of this study was to investigate whether a six-week moderate-intensity swimming intervention with added respiratory dead space (ARDS) resulted in any differences in respiratory muscle variables and pulmonary function in recreational swimmers. A sample of 22 individuals (recreational swimmers) were divided into an experimental (E) and a control (C) group, observed for maximal oxygen uptake (VO2max). The intervention involved 50 min of front crawl swimming performed at 60% VO2max twice weekly for six weeks. Added respiratory dead space was induced via tube breathing (1000 mL) in group E during each intervention session. Respiratory muscle strength variables and pulmonary and respiratory variables were measured before and after the intervention. The training did not increase the inspiratory or expiratory muscle strength or improve spirometric parameters in any group. Only in group E, maximal tidal volume increased by 6.3% (p = 0.01). The ARDS volume of 1000 mL with the diameter of 2.5 cm applied in moderate-intensity swimming training constituted too weak a stimulus to develop respiratory muscles and lung function measured in the spirometry test.

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