Predictive value of the Spinal Instability Neoplastic Score for Survival and Ambulatory Function After Surgery for Metastatic Spinal Cord Compression in 110 Patients With Prostate Cancer

Spine ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Johan Wänman ◽  
Johannes Jernberg ◽  
Patrik Gustafsson ◽  
Kasim Abul-Kasim ◽  
Pawel Grabowski ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Predictive Value ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Spinal Instability

Analysis of Clinical Features of Patients with Metastatic Spinal Cord Compression Caused by Prostate Cancer

2009 ◽  
Vol 50 (12) ◽  
pp. 1174
Author(s):  
Sungwoo Hong ◽  
Dalsan You ◽  
In Gab Jeong ◽  
Jun Hyuk Hong ◽  
Hanjong Ahn ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Spinal Cord ◽  
Clinical Features ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression

scholarly journals Surgical Decompression of High-Grade Spinal Cord Compression from Hormone Refractory Metastatic Prostate Cancer

Neurosurgery ◽  
2017 ◽  
Vol 82 (5) ◽  
pp. 670-677
Author(s):  
Muhammad Omar Chohan ◽  
Sweena Kahn ◽  
Gustav Cederquist ◽  
Anne S Reiner ◽  
Joseph Schwab ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Median Overall Survival ◽  
Cord Compression ◽  
Spinal Instability ◽  
High Grade ◽  
Hormone Sensitive ◽  
Hormone Refractory ◽  
Spine Disease

Abstract BACKGROUND Spine and nonspine skeletal metastases occur in more than 80% of patients with prostate cancer. OBJECTIVE To examine the characteristics of the patient population undergoing surgery for the treatment of prostate cancer metastatic to the spine. METHODS A retrospective chart review was performed on all patients treated at our institution from June 1993 to August 2014 for surgical management of metastatic spine disease from prostate cancer. RESULTS During the study period, 139 patients with 157 surgical lesions underwent surgery for metastatic spine disease. Decompression for high-grade epidural spinal cord compression was required for 126 patients with 143 lesions. Preoperatively, 69% had a motor deficit and 21% were nonambulatory, with 32% due to motor weakness. At surgery, 87% of patients had hormone-refractory prostate cancer (HRPC) and 61% failed prior radiation. Median overall survival for HRPC patients was 6.6 mo (95% confidence interval [CI]: 5.6-8.6) while the median overall survival for hormone-sensitive patients was 16.3 mo (95% CI: 4.0-26.6). CONCLUSION The majority of patients undergoing surgery for prostate cancer metastases to the spine were refractory to hormone therapy, indicating that patients with hormone-sensitive prostate cancer are unlikely to develop symptomatic spinal cord compression or spinal instability. A significant number of HRPC patients presented with neurological deficits attributable to spinal cord compression. Vigilant monitoring for the development of signs and symptoms of epidural spinal cord compression and spinal instability in hormone-refractory patients is recommended. Surgical decision making may be affected by the much shorter postoperative survival for HRPC patients as compared to patients with hormone-sensitive cancer.

scholarly journals Outcome after surgery for metastatic spinal cord compression in 54 patients with prostate cancer

2011 ◽  
Vol 83 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Sead Crnalic ◽  
Christer Hildingsson ◽  
Pernilla Wikström ◽  
Anders Bergh ◽  
Richard Löfvenberg ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression

scholarly journals Metastatic spinal cord compression by gastric cancer: a case report

2019 ◽  
Vol 2019 (9) ◽  
Author(s):  
Teiko Kawahigashi ◽  
Takashi Kawabe ◽  
Hirokazu Iijima ◽  
Yuto Igarashi ◽  
Yuma Suno ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gastric Cancer ◽  
Spinal Cord ◽  
Case Report ◽  
Spinal Cord Compression ◽  
Early Treatment ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Lower Limbs ◽  
Prompt Diagnosis

Abstract Metastatic spinal cord compression (MSCC) is one of the serious complications of malignancy. Most cases of MSCC occur from breast or prostate cancer primaries; MSCC secondary to gastric cancer is rare. We herein report a case of a patient with gastric cancer with weakness of the lower limbs and urinary retention on initial presentation. This case demonstrates that although rare, bone metastases and MSCC may occur from gastric primaries. It also highlights the importance of prompt diagnosis and early treatment of MSCC.

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