scholarly journals Antimicrobial Susceptibility Patterns of Escherichia coli among Tunisian Outpatients with Community-Acquired Urinary Tract Infection (2012–2018): Erratum

2021 ◽  
Vol 15 (4) ◽  
pp. 241
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Patterns

scholarly journals Antimicrobial Susceptibility Patterns of Escherichia coli among Tunisian Outpatients with Community-Acquired Urinary Tract Infection (2012-2018)

2020 ◽  
Vol 14 (4) ◽  
pp. 200-205
Author(s):  
Nawel Daoud ◽  
Manel Hamdoun ◽  
Hela Hannachi ◽  
Chedlia Gharsallah ◽  
Wiem Mallekh ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Clavulanic Acid ◽  
Antimicrobial Susceptibility ◽  
Diffusion Method ◽  
E Coli ◽  
Amoxicillin Clavulanic Acid ◽  
Susceptibility Patterns

<b><i>Introduction:</i></b><b> </b>Community-acquired urinary tract infection is one of the most common reasons for consultation in everyday practice; it represents a major source of antibiotic consumption. <i>Escherichia coli</i> (<i>E. coli</i>) is the main pathogen incriminated. <b><i>Objective:· </i></b>The aim of this study was to evaluate antimicrobial susceptibility patterns of community-acquired uropathogenic <i>E coli</i> throughout a 7-year period. <b><i>Methodology:</i></b><b> </b>All strains of <i>E. coli</i> isolated from urine samples between January 1st 2012 and December 31st 2018 were included. Presence of ≥ 10<sup>3</sup> CFU/ml in urine culture media was considered as significant for urinary tract infection. The identification of <i>E. coli</i> strains was realized using standard laboratory techniques. Antibiotic susceptibility testing was performed using the disk diffusion method according to the CA-SFM/ EUCAST criteria. <b><i>Results: </i></b>A total of 1,335 <i>E. coli</i> strains were isolated. Overall susceptibility rates to antimicrobial agents were as follows: ampicillin 39.1%, amoxicillin-clavulanic acid 64.9%, cefotaxime 94.9%, trimethoprim/sulfamethox-azole 67.6%, ciprofloxacin 89.2%, ofloxacin 86.9%, amikacin 98.6%, gentamicin 93.9%, nitrofurantoin 97.6% and fosfomycin 99.3%. All isolates were susceptible to carbapenems. The frequency of extended spectrum beta-lactamases-producing <i>E. coli</i> strains was 4.7%. Susceptibility rates of <i>E. coli</i> for ampicillin, trimethoprim/sulfamethoxazole and amikacin remained relatively stable over the study period, whereas susceptibility to amoxicillin-clavulanic acid, cefotaxime and fluoroquinolones showed a 2-phase pattern. As for gentamicin, a continuous decrease in susceptibility rates was observed. <b><i>Conclusion:</i></b><b> </b>Antimicrobial susceptibility profiles of uropathogenic <i>E. coli</i> are constantly changing, due to modifications in the antibiogram interpretation criteria and antibiotic prescription habits. Rigorous surveillance of resistance rate is necessary to determine appropriate empirical treatment and limit the spread of multiresistant strains.

scholarly journals Virulence-associated genes and drug susceptibility patterns of uropathogenic Escherichia coli isolated from patients with urinary tract infection

2019 ◽  
Vol Volume 12 ◽  
pp. 2039-2047 ◽  
Author(s):  
Ahmad Farajzadeh Sheikh ◽  
Hamed Goodarzi ◽  
Mohammad Jaafar Yadyad ◽  
Sajad Aslani ◽  
Mansour Amin ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Drug Susceptibility ◽  
Susceptibility Patterns

scholarly journals Antimicrobial susceptibility pattern of urine culture isolates in a tertiary care hospital of Jharkhand, India

2017 ◽  
Vol 6 (7) ◽  
pp. 1733 ◽  
Author(s):  
Akhilesh Kumar ◽  
Rajiv Kumar ◽  
Manju Gari ◽  
Uma Shanker P. Keshri ◽  
Sumit K. Mahato ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Urine Culture ◽  
Tertiary Care ◽  
Susceptibility Pattern ◽  
Antimicrobial Susceptibility Pattern ◽  
The Common

Background: Urinary tract infection (UTI) is one of the common infections encountered by the clinicians. Though a good number of antimicrobial agents are available, still UTIs have become difficult to treat due to development of resistance by the uropathogens. So, regional data regarding the common uropathogens and their sensitivity pattern is required to guide the clinicians to start empirical therapy while managing UTIs. The purpose of the study was to identify different species of microorganisms, along with their antimicrobial susceptibility pattern, causing urinary tract infection in outpatient and indoor patients at RIMS, Ranchi, Jharkhand.Methods: Observational study was conducted using urine culture and sensitivity reports collected retrospectively from records maintained in the department of Microbiology over a period from July 2016 to Feb 2017 in tertiary care hospital.Results: UTI was more common in females (57.74%) than in males (42.26%). Among the uropathogens isolated Escherichia coli (37.41%) was found to be the predominant organism followed by Klebsiella species (32.79%), Pseudomonas species (25.86%), and gram-positive bacteria Staphylococcus aureus accounted (3.92%) of total cases. The most common isolates were E. coli showed high sensitivity to amikacin (79.24%), followed by levofloxacin (77.21%) and gentamycin (62.26%). It was found to be resistant to norfloxacin (86%), nalidixic acid (86.76%) and cefotaxime (69.88%).Conclusions: Though various microorganisms are responsible for UTI. Escherichia coli species is the most common organism. Antimicrobial resistance has already emerged against many antibiotics, making empirical treatment of these infections challenging.

Study of Bacterial Pathogens in Urinary Tract Infection and their Antimicrobial Sensitivity Pattern

2018 ◽  
Vol 4 (2) ◽  
pp. 40-44
Author(s):  
Rezina Parveen ◽  
Ina Rahim
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Urine Samples ◽  
College Hospital ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Patient Department

Background: Urinary tract infection (UTI) is one of the most common bacterial infections in Bangladesh. Antimicrobial agents are used for its treatment. The increase in antibiotic resistance among uropathogens is a global problem.Objective: This study was designed to find out the prevalence of UTI, its causative agents and their antimicrobial susceptibility patterns among suspected patients of UTI attending Dhaka Dental College Hospital, Dhaka.Methodology: This cross-sectional study was carried out in Dhaka Dental College Hospital, Dhaka during the period of November 2014 to May 2017. Clinically diagnosed cases of UTI irrespective of age and sex from out-patient department and in-patient department were selected for the purpose of the study. For culture, the urine samples were inoculated on 5% sheep blood agar and MacConkey’s agar media using calibrated loop following standard bacteriological technique. After the incubation period, the plate were examined for bacterial pathogen. The disk diffusion method (Kirby Bauer’s) was used to determine the antimicrobial susceptibility of isolates. Standard inoculums were inoculated on Mueller-Hinton agar and incubated at 37oC for 24 hours.Result: Ninety three urine samples were studied. Among the 93 samples most of them were in the age group of 21 to 30 years. Out of 93 samples, 26 (27.95%) samples were found culture positive. Escherichia coli (92.30%) was found to be the predominant organism.  Regarding antimicrobial sensitivity pattern Esch. coli was found to be most sensitive to Imipenem (100%), Amikacin (87.5%), and Nitrofurantoin (83.33%).Conclusion: In conclusion young aged female are commonly suffering from UTI and Escherichia coli is the most common isolated bacteria.Bangladesh Journal of Infectious Diseases, December 2017;4(2):40-44

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