Lymph Node Involvement by a Clear Cell Nodular Hidradenoma-Like Tumor of Uncertain Malignant Potential

2017 ◽  
Vol 39 (12) ◽  
pp. 953-954 ◽  
Author(s):  
Brandon Au ◽  
Konstantinos G. Sidiropoulos ◽  
Danny Ghazarian ◽  
Michael Sidiropoulos
Keyword(s):  
Lymph Node ◽  
Clear Cell ◽  
Lymph Node Involvement ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Node Involvement ◽  
Nodular Hidradenoma

Uterine Papillary Serous, Clear Cell, and Poorly Differentiated Endometrioid Carcinomas: A Comparative Study

2011 ◽  
Vol 21 (4) ◽  
pp. 661-667 ◽  
Author(s):  
Stefano Greggi ◽  
Giorgia Mangili ◽  
Cono Scaffa ◽  
Felice Scala ◽  
Simona Losito ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Lymph Node ◽  
Clear Cell ◽  
Myometrial Invasion ◽  
Lymph Node Involvement ◽  
Peritoneal Metastases ◽  
Node Involvement ◽  
Poorly Differentiated ◽  
Independent Risk Factors ◽  
Nuclear Ploidy

Introduction:Uterine papillary serous and clear cell carcinomas (UPSCs/CCs) show a different spreading from that of poorly differentiated endometrioid carcinomas (PDECs) and are usually thought to be prognostically more aggressive than PDECs. On the contrary, it has been recently claimed that UPSC/CC and PDEC have a similar prognosis. In this retrospective study on 2 institutional databases, the surgical-pathological data and survival have been compared in patients with UPSC/CC and PDEC.Methods:A total of 139 surgically staged consecutive patients, 63 with UPSC/CC (37 UPSC; 26 CC) and 76 with PDEC clinically limited to the uterine corpus, have been compared for nuclear ploidy, myometrial invasion, (occult) cervical extension, peritoneal, and lymph node metastasis. Prognostic factors have been correlated through multivariate analysis with survival (disease-specific [DSS] and disease-free [DFS]).Results:Peritoneal metastases and aneuploidy were found to be the only parameters significantly different in the 2 groups: peritoneal metastases 28.6% in UPSC/CC (extrapelvic 19%) and 7.9% in PDEC (extrapelvic 2.6%) (P= 0.001), aneuploidy 48.6% in UPSC/CC and 30.6% in PDEC (P= 0.05). Five-year DSS was 57.9% versus 75.2% (P= 0.02), and DFS was 52.3% versus 71.4% (P= 0.04) for UPSC/CC and PDEC, respectively. All but cervical and lymph node involvement were significant predictors of survival. After multivariate analysis, histotype (DSS: hazard ratio [HR], 1.98; 95% confidence interval [CI], 1.02-3.86;P= 0.04; DFS: HR, 1.94; 95% CI, 1.04-3.63;P= 0.04), stage (DSS: HR, 2.26; 95% CI, 1.10-4.65;P= 0.03; DFS: HR, 2.21; 95% CI, 1.12-4.38;P= 0.02), and myometrial invasion (DSS: HR, 2.86; 95% CI, 1.22-6.69;P= 0.01; DFS: HR, 3.96; 95% CI, 1.63-9.62;P= 0.002) were independent risk factors for survival.Conclusions:Uterine papillary serous and clear cell carcinomas spread to abdominal peritoneum more frequently than PDEC; multivariate analysis confirms UPSC/CC as an independent, unfavorable predictor of outcome.

Surgical staging for epithelial ovarian tumors of low malignant potential

1994 ◽  
Vol 4 (5) ◽  
pp. 310-314 ◽  
Author(s):  
F. Di Re ◽  
R. Fontanelli ◽  
F. Raspagliesi ◽  
D. Paladini ◽  
E. A.A. Feudale
Keyword(s):  
Lymph Node ◽  
Lymph Node Involvement ◽  
Pelvic Lymphadenectomy ◽  
Malignant Potential ◽  
Ovarian Tumors ◽  
Low Malignant Potential ◽  
Node Involvement ◽  
Node Metastases ◽  
Group 2 ◽  
Group 1

From January 1975 to December 1991, 34 patients with a diagnosis of epithelial ovarian tumors of low malignant potential (LMP) were admitted to the Istituto Nazionale Tumori of Milan. Eighteen of them (group 1) underwent complete staging laparotomy and retroperitoneal para-aortic and pelvic lymphadenectomy, as for ovarian cancer. In the remaining 16 cases (group 2), the surgical treatment ranged from unilateral oophorectomy to incomplete staging procedure. In group 1, nine patients (50%) were found to have retroperitoneal nodal involvement. In group 2, all patients had stage I disease. Patients were followed up for 20–222 months (mean 108, median 86). There were two recurrences in group 2 (after 5 years) and none in group 1 (NS). Currently all patients are alive and disease free. Nine of 18 group 1 patients were upstaged to stage III on the basis of lymph node involvement only. However, at least in this retrospective series, lymph node metastases did not affect prognosis or survival.

Three Cases of Clear Cell Hidradenoma With “Benign” Lymph Node Involvement

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Guillermo Gonzalez-Lopez ◽  
Maria C. Garrido-Ruiz ◽  
Juan J. Rios-Martin ◽  
Jose L. Rodriguez-Peralto
Keyword(s):  
Lymph Node ◽  
Clear Cell ◽  
Lymph Node Involvement ◽  
Node Involvement ◽  
Benign Lymph Node

scholarly journals Evaluation of Effect of Lymph Node Involvement on Prognosis of Clear Cell Renal Cell Cancer and Role of Tumor Size and Grade on Prediction of Lymph Node Involvement

2014 ◽  
Vol 13 (4) ◽  
pp. 192-195
Author(s):  
Nurullah Hamidi ◽  
Mehmet İlker Gökçe ◽  
Evren Süer ◽  
Sümer Baltacı ◽  
Yaşar Bedük
Keyword(s):  
Lymph Node ◽  
Renal Cell Cancer ◽  
Tumor Size ◽  
Renal Cell ◽  
Clear Cell ◽  
Cell Cancer ◽  
Lymph Node Involvement ◽  
Node Involvement

scholarly journals An Unusual Case of Lower Extremity Clear Cell Hidradenocarcinoma

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Marc Rafols ◽  
Odille Mejia ◽  
Kei Shing Oh ◽  
Blake Bendixen ◽  
Irving Jorge ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lower Extremity ◽  
Unusual Case ◽  
Clear Cell ◽  
Metastatic Potential ◽  
Lymph Node Involvement ◽  
Gland Tumor ◽  
Sweat Gland Tumor ◽  
Node Involvement ◽  
Head Neck

Hidradenocarcinoma (HC) is a rare malignant sweat gland tumor with metastatic potential primarily located in the head, neck, and trunk. We present an unusual case of a large lower extremity Clear Cell HC managed with surgical resection and adjuvant locoregional radiation after excluding lymph node involvement.

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