Cutaneous Pseudolymphoma With Langerhans Cell Hyperplasia—A Rare Case With Clinical Presentation Mimicking Malignancy and Potential Diagnostic Pitfall

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Cian-Hao Ye ◽  
Chih-Jung Chen ◽  
Kung-Chao Chang ◽  
Yu-Hung Wu ◽  
Mei-Ling Chen ◽  
...  
Keyword(s):  
Rare Case ◽  
Clinical Presentation ◽  
Langerhans Cell ◽  
Cell Hyperplasia ◽  
Diagnostic Pitfall ◽  
Cutaneous Pseudolymphoma

scholarly journals Advanced ulcerative tumefactive lesions of the mucocutaneous surface in previously unrecognized Langerhans Cell Histiocytosis

2021 ◽  
Vol 12 (4) ◽  
pp. 419-421
Author(s):  
Fatima Azzahra Elgaitibi ◽  
Soumaya Hamich ◽  
Noureddine Mahiou
Keyword(s):  
Langerhans Cells ◽  
Langerhans Cell Histiocytosis ◽  
Rare Case ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Systemic Disease ◽  
Skin Lesions ◽  
Clinical Suspicion ◽  
Langerhans Cell ◽  
Multiple Ulcers

Langerhans cell histiocytosis (LCH) is an uncommon systemic disease characterized by the infiltration of one organ or more by Langerhans cells. Its clinical presentation is heterogeneous and depends on the affected organs. We report the rare case of a 43-year-old female presenting herself with central diabetes insipidus and receiving nasal desmopressin spray. Later, the patient developed multiple papules and pustules progressing to multiple ulcers affecting the retroauricular and axillary folds, as well as the oral and genital mucosas. The skin lesions had been evolving for several months. A histopathological examination of a skin biopsy confirmed the clinical suspicion of LCH.

scholarly journals Neonatal pertusis with classical whoop: an unusual scenario

2018 ◽  
Vol 5 (6) ◽  
pp. 2344
Author(s):  
Payas Joshi ◽  
Sumit Bhatia ◽  
Jay Kishore ◽  
Chetnanand Jhaz
Keyword(s):  
Early Diagnosis ◽  
Rare Case ◽  
Clinical Presentation ◽  
Age Groups ◽  
Early Infancy ◽  
Atypical Presentation ◽  
Older Children ◽  
The Times

Pertusis affects all the age groups but is most severe in neonates and early infancy and may even cause mortality. Clinical presentation of neonatal pertusis is varied and thus knowing the spectrum of clinical presentation is vital for early diagnosis. Unlike older children, most of the times neonatal pertusis has an atypical presentation and classical presentation is very rare. Here we present such a rare case of neonatal pertusis who presented with classical symptoms of pertusis.

scholarly journals Complex-Compound Odontoma: A Rare Clinical Presentation

2018 ◽  
pp. 39-44
Author(s):  
Damla Torul DDS, PhD ◽  
Metehan Keskin DDS ◽  
Seda Gun DDS, PhD ◽  
Didem Odabasi DDS, PhD
Keyword(s):  
Early Detection ◽  
Complex Compound ◽  
Rare Case ◽  
Multidisciplinary Approach ◽  
Clinical Presentation ◽  
Odontogenic Tumor ◽  
Compound Odontoma

Odontomas can be detected as complex or compound variants and they rarely show the histologic characteristics of both types together. The tumor commonly associated with malocclusion, eruption disturbances and pathological anomalies, but they seldom cause bony expansion. Early detection and management of odontoma with multidisciplinary approach pose an important role to prevent disturbances associated with this common odontogenic tumor. Here we report a rare case of an odontoma which show the features of both complex and compound types and also cause bony expansion, eruption failure in an 8-year-old boy.

scholarly journals Diagnosis of a Rare Case of Acromegaly Secondary to Pituitary Macroadenoma Debuting as Sudden DKA

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A581-A582
Author(s):  
Ivan Augusto Rivera Nazario ◽  
Kyomara Hernandez Moya ◽  
Arnaldo Nieves Ortiz ◽  
Jose Ayala Rivera ◽  
Arnaldo Rojas Figueroa ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Growth Hormone ◽  
Pituitary Adenomas ◽  
Rare Case ◽  
Clinical Presentation ◽  
De Novo ◽  
Signs And Symptoms ◽  
Careful Consideration ◽  
Clinical Syndrome ◽  
The Past

Abstract Acromegaly is an uncommon clinical syndrome that results from excessive secretion of growth hormone with an annual incidence of 6 to 8 cases per 1 million of individuals with a mean age of diagnosis between 40-45 years. Pituitary adenomas can be the principal reason for an overgrowth of the anterior pituitary somatotroph cells, and account for approximately one-third of all hormone-secreting pituitary adenomas with a prevalence of about 38-69 cases per 1 million and an incidence of 3-4 cases per 1 million individuals. The onset of acromegaly is insidious, and its progression is usually very slow. At the moment of diagnosis, approximately 75% of patients have presence of macro adenomas, but most cases are diagnosed after several laboratory workups and incidental brain imaging. A characteristic clinical presentation of pituitary adenomas could be secondary to mass effect. Metabolic presentation such as diabetes is one of the most common related conditions preceding the diagnosis of acromegaly. Clinical presentation with abrupt onset of DKA could be a determining factor on disease progression due to higher GH levels correlating with an increased prevalence of insulin resistance. We present a rare case of a 28y/o female G5P3A2 without previous PMHx who presented to ER with abdominal pain, general malaise, slurred speech, headache and gait difficulty of 3 days of evolution. Upon initial evaluation at ER patient was found with hyperglycemia of 317mg/dL, low central bicarbonate, high anion gap and positive serum ketones suggestive of DKA de novo. Based on neurological complaints, head CT performed showed an incidental parasellar/suprasellar/temporal hyperdense mass measuring 2.5cm x 2.6cm with optic chiasm compression features. Upon further specific questioning patient referred amenorrhea for the past 3 years, bitemporal hemianopsia, galactorrhea and marked facial feature changes, frontal bossing, weight gain, and acanthosis nigricans, for the past year. Pituitary adenoma workup revealed low prolactin levels (1.38), markedly increased growth hormone (501) and IGF-1 (893) suggesting diagnosis of acromegaly, most likely secondary to a functioning macroadenoma. Patient initially treated with Cabergoline, uncontrolled diabetes was managed and was referred to Neurosurgery service for further evaluation and tumor removal. Based on current literature, the incidence of acromegaly cases is low, more specifically when presenting with new onset diabetic ketoacidosis, insulin resistance and secondary to functioning macroadenomas. Medical awareness should be promoted to assess for careful consideration of signs and symptoms, workup, management and treatment to assess and minimize further health complications and physical burdens acromegaly and pituitary adenomas could pose for affected individuals.

scholarly journals Inflammatory Pseudotumour of Stomach in an old lady: a rare case report

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Azhar AH ◽  
Pasha MA ◽  
Hassan S ◽  
Zainal M ◽  
Rashidi A
Keyword(s):  
Case Report ◽  
Solid Tumor ◽  
Rare Case ◽  
Clinical Presentation ◽  
Inflammatory Pseudotumour ◽  
Secondary Neoplasms ◽  
Laboratory Techniques ◽  
Clinical Presentations ◽  
Rare Case Report ◽  
Adults And Children

Inflammatory pseudotumour (IPT) is a rare benign solid tumor in adults and children. The prevalence, etiology and pathogenesis of this condition are still uncertain. Despite the use of modern laboratory techniques and imaging, it is often difficult to make the diagnosis of IPT. Besides, occasionally the nonspecific morphological appearance and clinical presentation of the mass may mimic other more common primary or secondary neoplasms. IPT is commonly encountered in the lung and mediastinum. Other sites include abdomen (liver, pancreas, stomach, omentum), retroperitoneum, pelvis (bladder) and extremities in children. We report a rare case of gastric inflammatory pseudotumour in a 65-year-old female patient. Clinical presentations and its management along with review of literatures are presented.

A RARE CASE REPORT OF SUBDURAL HAEMATOMA WITH ANEMIA APLASTIC

2021 ◽  
Vol 27 (2) ◽  
pp. 124-128
Author(s):  
Feda Anisah Makkiyah ◽  
Rahmah Hida Nurrizka
Keyword(s):  
Case Report ◽  
Aplastic Anemia ◽  
Subdural Hematoma ◽  
Rare Case ◽  
Subdural Haematoma ◽  
Blood Smear ◽  
Clinical Presentation ◽  
Headache Disorder ◽  
Peripheral Blood Smear ◽  
Rare Case Report

Objective and Importance. To illustrate the development of a rare case of spontaneous subdural hematoma (SDH)  secondary to aplastic anemia and conservative treatment of SDH. Clinical Presentation. A 43-year-old male complained of severe progressive headaches that starting from one month ago. His laboratory values showed pancytopenia and his peripheral blood smear showed no abnormalities except lack of the number of erythrocytes, leukocyte, and thrombocyte and we could not find any malignancy in the smear. He experienced headache,  disorder of balance and decrease of consciousness  CT imaging of the head showed  a 7.0 cm (2 cm thickness) left frontal-parietal subdural hematoma. Conclusion. Aplastic anemia is a rare case with manifested of subdural hematoma.

Sign in / Sign up

Export Citation Format

Share Document