Pimavanserin, a 5-HT2A receptor inverse agonist, reverses psychosis-like behaviors in a rodent model of Alzheimer’s disease

Receptor Inverse Agonist

Pimavanserin, a 5HT 2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease

Journal of Neurochemistry ◽

10.1111/jnc.15260 ◽

2020 ◽

Author(s):

Carla M. Yuede ◽

Clare E. Wallace ◽

Todd A. Davis ◽

Woodrow D. Gardiner ◽

Jane C. Hettinger ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Inverse Agonist ◽

Aβ Production ◽

Receptor Inverse Agonist

Transcranial direct current stimulation does not improve memory deficits or alter pathological hallmarks in a rodent model of Alzheimer's disease

Journal of Psychiatric Research ◽

10.1016/j.jpsychires.2019.04.016 ◽

2019 ◽

Vol 114 ◽

pp. 93-98 ◽

Cited By ~ 5

Author(s):

Elise Gondard ◽

Maria Luisa Soto-Montenegro ◽

Amanda Cassol ◽

Andres M. Lozano ◽

Clement Hamani

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Direct Current ◽

Transcranial Direct Current Stimulation ◽

Memory Deficits ◽

Rodent Model ◽

Direct Current Stimulation ◽

O2-05-06: Pilot randomized controlled study of a histamine receptor inverse agonist in the symptomatic treatment of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2011.05.871 ◽

2011 ◽

Vol 7 ◽

pp. S300-S300

Author(s):

Michael Egan ◽

Roy Yaari ◽

Lian Liu ◽

Michael Ryan ◽

Yahong Peng ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Symptomatic Treatment ◽

Histamine Receptor ◽

Inverse Agonist ◽

Randomized Controlled Study ◽

Controlled Study ◽

Randomized Controlled ◽

Receptor Inverse Agonist

Dysfunctional microglia:neuron interactions with significant female bias in a developmental gene x environment rodent model of Alzheimer's disease

International Immunopharmacology ◽

10.1016/j.intimp.2019.03.039 ◽

2019 ◽

Vol 71 ◽

pp. 241-250 ◽

Cited By ~ 1

Author(s):

A.N. vonderEmbse ◽

Q. Hu ◽

J.C. DeWitt

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Rodent Model ◽

Developmental Gene ◽

Female Bias

Age-Specific Retinal and Cerebral Immunodetection of Amyloid-β Plaques and Oligomers in a Rodent Model of Alzheimer’s Disease

Journal of Alzheimer s Disease ◽

10.3233/jad-191346 ◽

2020 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Umma Habiba ◽

Sam Merlin ◽

Jeremiah K.H. Lim ◽

Vickie H.Y. Wong ◽

Christine T.O. Nguyen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Β ◽

Rodent Model ◽

Barriers to developing a valid rodent model of Alzheimer's disease: from behavioral analysis to etiological mechanisms

Frontiers in Neuroscience ◽

10.3389/fnins.2015.00245 ◽

2015 ◽

Vol 9 ◽

Cited By ~ 14

Author(s):

Darryl C. Gidyk ◽

Scott H. Deibel ◽

Nancy S. Hong ◽

Robert J. McDonald

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Rodent Model ◽

Behavioral Analysis ◽

The protective effect of Indian Catechu methanolic extract against aluminum chloride-induced neurotoxicity, A rodent model of Alzheimer's disease

Heliyon ◽

10.1016/j.heliyon.2021.e06269 ◽

2021 ◽

Vol 7 (2) ◽

pp. e06269

Author(s):

Ekramy Elmorsy ◽

Eman Elsharkawy ◽

Fahad A. Alhumaydhi ◽

Mohamed Salama

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Protective Effect ◽

Aluminum Chloride ◽

Methanolic Extract ◽

Rodent Model ◽

TIMP-1: A key cytokine released from activated astrocytes protects neurons and ameliorates cognitive behaviours in a rodent model of Alzheimer’s disease

Brain Behavior and Immunity ◽

10.1016/j.bbi.2020.03.014 ◽

2020 ◽

Vol 87 ◽

pp. 804-819 ◽

Cited By ~ 2

Author(s):

Pampa Saha ◽

Sukanya Sarkar ◽

Ramesh Kumar Paidi ◽

Subhas C. Biswas

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Rodent Model ◽

Cognitive Behaviours

Modulation cellular and neurobehavioural responses induced by resveratrol and environmental enrichment in rodent model of Alzheimer’s disease

10.26226/morressier.5b31ec432afeeb001345a792 ◽

2018 ◽

Author(s):

Mustapha Shehu Muhammad

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Environmental Enrichment ◽

Rodent Model ◽

The effects of a neuroligin-1-derived peptide on behaviour in the 5XFAD mouse model of Alzheimer's disease

10.26226/morressier.5785edc6d462b80296c991f6 ◽

2016 ◽

Author(s):

Katrin Sonn

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

5Xfad Mouse