Corneal Nerve Alterations in Dry Eye-associated Ocular Surface Disease

2009 ◽  
Vol 49 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Mohammad H. Dastjerdi ◽  
Reza Dana
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Ocular Surface Disease ◽  
Corneal Nerve

Optimum | Tangible Hydra-PEG™ – Gaining Momentum in the Industry

The Eye ◽  
2021 ◽  
Vol 23 (4) ◽  
pp. 31-34
Author(s):  
M. Conway
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Surface Coating ◽  
Clinical Case ◽  
Contact Lenses ◽  
Ocular Surface Disease ◽  
Corneal Ectasia ◽  
Corneal Lens ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

The issue of hydrophilicity of the surface of gas permeable contact lenses remains one of the persistent problems. Tangible Hydra-PEG™ surface coating is applied to gas permeable contact lenses to significantly improve wettability and wearing comfort. Although it is mainly used to alleviate dry eye symptoms in scleral and corneal lens users, particularly for those patients with corneal ectasia and/or Ocular Surface Disease (OSD), it can be used in other modalities. This article describes the development of the product and describes the benefits of its use in a clinical case.

The Effect of Low-Dose Aspirin on Dry Eye Parameters and Ocular Surface Disease Index Questionnaire

2018 ◽  
Vol 34 (3) ◽  
pp. 256-259 ◽  
Author(s):  
Alper Yazıcı ◽  
Esin Sarı ◽  
Erkan Ayhan ◽  
Gözde Şahin ◽  
Nesime Setge Tıskaoğlu ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Low Dose ◽  
Disease Index ◽  
Ocular Surface Disease ◽  
Ocular Surface Disease Index ◽  
Dose Aspirin ◽  
Low Dose Aspirin

IN VIVO CONFOCAL MICROSCOPY FOR STUDYING CORNEAL DISEASES/CONDITIONS ASSOCIATED WITH CORNEAL NERVE DAMAGE AND OCULAR SURFACE DISEASE.

Cornea ◽  
2000 ◽  
Vol 19 (Supplement 2) ◽  
pp. S131
Author(s):  
T Tervo ◽  
T U Valle ◽  
J AO Moilanen ◽  
M E Rosenberg ◽  
I SJ Tuominen ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Ocular Surface ◽  
Nerve Damage ◽  
Ocular Surface Disease ◽  
In Vivo Confocal Microscopy ◽  
Corneal Nerve

scholarly journals Analysis of Clinical Characteristics of Immune-Related Dry Eye

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Hua Wang ◽  
Ping-Bao Wang ◽  
Ting Chen ◽  
Jing Zou ◽  
Ya-Jia Li ◽  
...  
Keyword(s):  
Dry Eye ◽  
Lupus Erythematosus ◽  
Ocular Surface ◽  
Clinical Characteristics ◽  
Nerve Fibers ◽  
Immune System Diseases ◽  
Corneal Nerve ◽  
The Difference ◽  
Surface Inflammation ◽  
Ocular Surface Inflammation

Aim. To discuss the clinical characteristics of immune-related dry eye. Methods. Simple dry eye (SDE) group: we selected 224 patients of simple dry eye with no systemic lesions. Immune-related dry eye (IRDE) group: we selected 207 patients of dry eye complicated with immune system diseases, including 70 cases of Sjögren’s syndrome (SS), 72 cases of systemic lupus erythematosus (SLE), and 65 cases of rheumatoid arthritis (RA). The classification of all patients was performed. The difference between the two groups was compared, including age, gender, ocular surface fluorescein staining and inflammatory reaction, tear breakup time (TBUT), Shirmer I test, confocal microscopy scan, and dry eye grading. Results. Compared with the SDE group, the patients of IRDE group were younger (P<0.05). The female patients were significantly more than the male ones (P<0.05). Corneal staining counts and ocular surface inflammation were significantly increased (P<0.05). TBUT and Shirmer I test shortened significantly (P<0.05). Corneal nerve fibers were less, and the number of local lymphocyte was significant increased. The number of dry eye patients in the moderate or above IRDE group was significantly increased (P<0.05). Conclusions. The dry eye symptom and sign and ocular surface inflammation of IRDE were significantly more severe than those of the SDE.

scholarly journals Pepys's Eyes: A Modern Answer to an Old Conundrum?

2020 ◽  
Vol 3 (1) ◽  
pp. e27-e40
Author(s):  
David Harries
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Diagnostic Algorithm ◽  
Dry Eye Disease ◽  
Ocular Surface Disease ◽  
Eye Disease ◽  
Samuel Pepys

Samuel Pepys was forced to abandon his renowned diary because of increasing pain and fear of impending blindness. In addition to having refraction errors, it has been suggested that he may have had ocular surface disease to account for his hitherto unexplained photophobia. This article uses new resources to re-examine Pepys’s symptoms working on the hypothesis that he suffered from dry eye disease. Applying the diagnostic algorithm provided by DEWS II corroborates the hypothesis and provides the basis of a unifying diagnosisof eye strain similar to digital eye strain that would explain all of his symptoms.

scholarly journals The effect of tamarind seed polysaccharidecontaining eye drop in dry eye syndrome: Results of an interventional, comparative, clinical study

2021 ◽  
Vol 2 (2) ◽  
pp. 71-76
Author(s):  
Naser Nozari ◽  
Shahrokh Ramin
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Dry Eye Disease ◽  
Ocular Surface Disease ◽  
Eye Disease ◽  
Eye Drops ◽  
Artificial Tears ◽  
Mean Values ◽  
The Mean ◽  
Contralateral Eye

Background: The mainstay of dry eye treatment is artificial tear solutions. Contralateral eye comparison of 2 types of artificial tears (Xiloial versus Tearlose) in managing dry eye disease was sought in this study. Methods: This study was a prospective, interventional, contralateral eye comparison of 2 types of artificial tears used for managing dry eye disease. The study participants were categorized into mild (13–22 points), moderate (23–32 points), or severe (33–100 points) ocular surface disease according to the baseline ocular surface disease index (OSDI) questionnaire score. Schirmer I and tear film break-up time (TBUT) tests, as well as detailed slit-lamp examinations, were performed at baseline and at the end of the study. All participants received Xiloial monodose eye drops for the right eye and Tearlose eye drops for the left eye, administered as a single drop 4 times per day. Furthermore, they were instructed to perform lid hygiene every 12 hours per day for both eyes. Results: Thirty-five patients (70 eyes) with a mean ± standard (SD) age of 50.2 ± 13.4 years were included, and 14 (40%) were men. The mean ± SD of the OSDI score was 44.24 ± 22.59 at baseline. Of the 35 patients, 10 (28.6%), 5 (14.3%), and 20 (57.1%) had mild, moderate, and severe ocular surface disease, respectively, according to the baseline OSDI score. Compared to baseline, the mean values of both TBUT and Schirmer I tests improved significantly in both groups (both P < 0.001). In comparing the final mean values between the 2 groups, this improvement was comparable for the Schirmer I test (P = 0.179), but TBUT in Tearlose-instilled eyes improved significantly more than in the fellow eyes (P < 0.001). Conclusions: Both Xiloial and Tearlose eye drops improved tear stability and tear production after a 2 week treatment period in eyes with dry eye disease. This improvement was comparable for tear production, but Tearlose-instilled eyes showed significantly greater improvement in tear stability. Further studies with longer follow-up and larger sample sizes could provide more reliable results as a basis for the clinical use of this TSP-containing lubricant eye drop solution in dry eye disease.

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