A Prospective Study of Early Intraocular Pressure Changes After a Single Intravitreal Triamcinolone Injection

PURPOSE: The study aims to evaluate the safety of topical corticosteroids Loteprednol and Flurometholone in treating VKC keeping in mind the efcacy of the drugs. METHOD: A prospective study was done including 200 eyes of 107 patients with severe VKC (grade 3,4). 7 patients were lost during follow up. Patients were selected randomly. 100 eyes of 50 patients were treated with Flurometholone 1% and another 100 eyes of 50 patients with Loteprednol 0.5%. All patients were followed up over a period of 3 months. The study duration is 18 months. RESULT: The normal IOP ranging between 10-21 mm Hg. Out of 100 eyes receiving urometholone in the study period of 18 months, 3 eyes (3%) showed IOP ≥ 30mm Hg and 5 eyes (5%) showed IOP between 21-30mm Hg. Out of the rest 100 eyes receiving Loteprednol, 3 eyes (3%) showed IOP between 21-30 mm Hg while none (0%) reached an IOP over 30 mm Hg. CONCLUSION: Loteprednol is more effective than Flurometholone and it consistently demonstrated a low propensity to elevate IOP, regardless of formulation, dosage regimen both during short term as well as long term treatment of VKC patient.

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Pseudohypopyon after intravitreal triamcinolone injection for the treatment of pseudophakic cystoid macular oedema

British Journal of Ophthalmology ◽

10.1136/bjo.2003.033589 ◽

2004 ◽

Vol 88 (6) ◽

pp. 843-844 ◽

Cited By ~ 33

Author(s):

S D M Chen

Keyword(s):

Macular Oedema ◽

Cystoid Macular Oedema ◽

Intravitreal Triamcinolone ◽

Triamcinolone Injection ◽

Intravitreal Triamcinolone Injection

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Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study

Journal of Clinical Medicine ◽

10.3390/jcm10163472 ◽

2021 ◽

Vol 10 (16) ◽

pp. 3472

Author(s):

Bojan Pajic ◽

Mirko Resan ◽

Brigitte Pajic-Eggspuehler ◽

Horace Massa ◽

Zeljka Cvejic

Keyword(s):

Circadian Rhythm ◽

Intraocular Pressure ◽

Minimally Invasive ◽

Prospective Study ◽

Cataract Surgery ◽

High Frequency ◽

Glaucoma Surgery ◽

Before And After ◽

Contact Lens Sensor ◽

A Prospective Study

Background: The aim of the study is to investigate whether the circadian IOP rhythm can be influenced by combined cataract surgery with high frequency deep sclerotomy (HFDS) and whether intraocular pressure (IOP) can be significantly reduced by HFDS. Methods: In our study 10 patients were included, in whom 24 h IOP monitoring was installed before and after HFDS/cataract surgery using a Triggerfish. HFDS is a minimally invasive glaucoma surgery (MIGS). Results: After performed HFDS combined with cataract surgery, the IOP was reduced from 27.7 ± 2.11 mmHg to 14.4 ± 2.59 mmHg, which is highly significant (p < 0.001). The contact lens sensor (CLS) cosinor analysis pre- and postoperatively showed that the circadian rhythm is not influenced by the surgery, i.e., the circadian IOP rhythm did not show significant differences before and after surgery. Conclusions: HFDS combined with cataract surgery is a potent surgical method that can significantly reduce the IOP. However, the circadian rhythm cannot be changed by the surgery. The acrophase remained during the night in all patients.

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