The Clinical and Molecular Epidemiology of Community- and Healthcare-Acquired Rotavirus Gastroenteritis

2008 ◽  
Vol 27 (1) ◽  
pp. 54-58 ◽  
Author(s):  
Michael J. Smith ◽  
H Fred Clark ◽  
Diane Lawley ◽  
Louis M. Bell ◽  
Richard L. Hodinka ◽  
...  
2018 ◽  
Vol 90 (6) ◽  
pp. 1040-1046 ◽  
Author(s):  
Nusrat Khandoker ◽  
Aksara Thongprachum ◽  
Sayaka Takanashi ◽  
Shoko Okitsu ◽  
Shuichi Nishimura ◽  
...  

2012 ◽  
Vol 33 (2) ◽  
pp. 64 ◽  
Author(s):  
Celeste Donato

Rotavirus is the principal aetiological agent of severe acute gastroenteritis in young children worldwide. Two vaccines, Rotarix [GlaxoSmithKline] and RotaTeq [Merck], have been developed to address the large burden of disease experienced worldwide. Both vaccines have been successful in decreasing morbidity and mortality associated with rotavirus gastroenteritis. Minor fluctuations in rotavirus epidemiology have been observed since vaccine introduction. However, it is unclear whether these observations are due to selection pressures specific to vaccine introduction or due to natural genotype fluctuations.


2016 ◽  
Vol 89 (5) ◽  
pp. 809-817 ◽  
Author(s):  
Ernest A. Wandera ◽  
Shah Mohammad ◽  
Satoshi Komoto ◽  
Yoshimasa Maeno ◽  
James Nyangao ◽  
...  

Pathology ◽  
2009 ◽  
pp. 1-5
Author(s):  
Tse Koh ◽  
Beng Low ◽  
Nicholas Leo ◽  
Li-Yang Hsu ◽  
Raymond Lin ◽  
...  

Background: Diarrhea is a main cause of morbidity and mortality in children under 5 years old. Globally it is responsible for approximately four billion cases and three million deaths annually. In developing countries, it causes two million deaths each year. The major causative organism is rotavirus which is responsible for one-third of hospitalizations with approximately 40% mortality. Objectives: To determine the prevalence and demographic characteristics of rotavirus infection in Babylon city, Iraq. Materials and Methods: Fecal samples were taken from children with age range of 6 months to 5 years complained of diarrhea during the period beginning in October 2016 till August 2017. The age, gender, residence, the type of feeding, place of the sample collection and duration of diarrhea were recorded. Specimens were analyzed by Latex test for detection of rotavirus. Results: A total of 349 children presented with diarrhea, the rotavirus antigen was detected in 169 fecal specimens from children with diarrhea (48%). More percentages of positive rotavirus specimens were seen in the 5year of age. No gender differences were observed, meanwhile samples obtained from rural areas and breastfed children showed less rotavirus positive infection. Conclusion: The present study confirms that rotavirus infection is still currently a prevalent gastroenteritis causative agent and required careful clinical attention. Pediatricians and health care providers are needed to be encouraged to take into account the children who at risk for developing rotavirus infection including age, residence and type of feeding.


Background: Diarrhea is a main cause of morbidity and mortality in children under 5 years old. Globally it is responsible for approximately four billion cases and three million deaths annually. In developing countries, it causes two million deaths each year. The major causative organism is rotavirus which is responsible for one-third of hospitalizations with approximately 40% mortality. Objectives: To determine the prevalence and demographic characteristics of rotavirus infection in Babylon city, Iraq. Materials and Methods: Fecal samples were taken from children with age range of 6 months to 5 years complained of diarrhea during the period beginning in October 2016 till August 2017. The age, gender, residence, the type of feeding, place of the sample collection and duration of diarrhea were recorded. Specimens were analyzed by Latex test for detection of rotavirus. Results: A total of 349 children presented with diarrhea, the rotavirus antigen was detected in 169 fecal specimens from children with diarrhea (48%). More percentages of positive rotavirus specimens were seen in the 5year of age. No gender differences were observed, meanwhile samples obtained from rural areas and breastfed children showed less rotavirus positive infection. Conclusion: The present study confirms that rotavirus infection is still currently a prevalent gastroenteritis causative agent and required careful clinical attention. Pediatricians and health care providers are needed to be encouraged to take into account the children who at risk for developing rotavirus infection including age, residence and type of feeding.


2011 ◽  
Vol 152 (16) ◽  
pp. 633-641 ◽  
Author(s):  
Katalin Gőcze ◽  
Katalin Gombos ◽  
Gábor Pajkos ◽  
Ingrid Magda ◽  
Ágoston Ember ◽  
...  

Cancer research concerning short non-coding RNA sequences and functionally linked to RNA interference (RNAi) have reached explosive breakthrough in the past decade. Molecular technology applies microRNA in extremely wide spectrum from molecular tumor prediction, diagnostics, progression monitoring and prevention. Functional analysis of tissue miRNA and cell-free serum miRNA in posttranscription and translation regulation innovated and restructured the knowledge on the field. This review focuses on molecular epidemiology and primary prevention aspects of the small non-coding RNA sequences. Orv. Hetil., 2011, 152, 633–641.


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