The Effect of Early Initiation of Antiretroviral Treatment in Infants on Pediatric AIDS Mortality in South Africa

2012 ◽  
Vol 31 (5) ◽  
pp. 474-480 ◽  
Author(s):  
Leigh F. Johnson ◽  
Mary-Ann Davies ◽  
Harry Moultrie ◽  
Gayle G. Sherman ◽  
Ruth M. Bland ◽  
...  
Health Policy ◽  
2011 ◽  
Vol 99 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Susan Cleary ◽  
Sheetal Silal ◽  
Stephen Birch ◽  
Henri Carrara ◽  
Victoria Pillay-van Wyk ◽  
...  

Author(s):  
Leigh F. Johnson ◽  
Rob E. Dorrington ◽  
Haroon Moolla

Background: The UNAIDS targets for 2020 are to achieve a 90% rate of diagnosis in HIVpositive individuals, to provide antiretroviral treatment (ART) to 90% of HIV-diagnosed individuals and to achieve virological suppression in 90% of ART patients.Objectives: To assess South Africa’s progress towards the 2020 targets and variations in performance by province.Methods: A mathematical model was fitted to HIV data for each of South Africa’s provinces, and for the country as a whole. Numbers of HIV tests performed in each province were estimated from routine data over the 2002–2015 period, and numbers of patients receiving ART in each province were estimated by fitting models to reported public and private ART enrolment statistics.Results: By the middle of 2015, 85.5% (95% CI: 84.5% – 86.5%) of HIV-positive South African adults had been diagnosed, with little variation between provinces. However, only 56.9% (95% CI: 55.3% – 58.7%) of HIV-diagnosed adults were on ART, with this proportion varying between 50.8% in North West and 72.7% in Northern Cape. In addition, 78.4% of adults on ART were virally suppressed, with rates ranging from 69.7% in Limpopo to 85.9% in Western Cape. Overall, 3.39 million (95% CI: 3.26–3.52 million) South Africans were on ART by mid- 2015, equivalent to 48.6% (95% CI: 46.0% – 51.2%) of the HIV-positive population. ART coverage varied between 43.0% in Gauteng and 63.0% in Northern Cape.Conclusion: Although South Africa is well on its way to reaching the 90% HIV diagnosis target, most provinces face challenges in reaching the remaining two 90% targets.


2021 ◽  
Vol 20 (1) ◽  
pp. 32-41
Author(s):  
Constance Mubekapi-Musadaidzwa ◽  
Dillon Wademan ◽  
Neshaan Peton ◽  
Portia Hendricks ◽  
Gabriela Carolus ◽  
...  

AIDS ◽  
2016 ◽  
Vol 30 (16) ◽  
pp. 2545-2550 ◽  
Author(s):  
Leigh F. Johnson ◽  
Olivia Keiser ◽  
Matthew P. Fox ◽  
Frank Tanser ◽  
Morna Cornell ◽  
...  

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