Description and Identification of the Peripheral Immune Response Trajectories Over Time in First-Time and Recurrent Stroke/Transient Ischemic Attack

2015 ◽  
Vol 47 (5) ◽  
pp. 256-262 ◽  
Author(s):  
Amy Miner Ross ◽  
Christopher S. Lee
Keyword(s):  
Immune Response ◽  
Transient Ischemic Attack ◽  
Recurrent Stroke ◽  
Peripheral Immune Response ◽  
Ischemic Attack ◽  
First Time ◽  
Over Time

Peripheral Immune Response and Infection in First-Time and Recurrent Ischemic Stroke or Transient Ischemic Attack

2014 ◽  
Vol 46 (4) ◽  
pp. 199-206 ◽  
Author(s):  
Amy Miner Ross ◽  
Christopher S. Lee ◽  
Margaret Brewer
Keyword(s):  
Immune Response ◽  
Ischemic Stroke ◽  
Transient Ischemic Attack ◽  
Peripheral Immune Response ◽  
Ischemic Attack ◽  
First Time

2014 Chinese guidelines for secondary prevention of ischemic stroke and transient ischemic attack

2017 ◽  
Vol 12 (3) ◽  
pp. 302-320 ◽  
Author(s):  
Yongjun Wang ◽  
Ming Liu ◽  
Chuanqiang Pu
Keyword(s):  
Ischemic Stroke ◽  
Secondary Prevention ◽  
Transient Ischemic Attack ◽  
Recurrent Stroke ◽  
Stroke Recurrence ◽  
Evidence Based ◽  
Cerebrovascular Disorder ◽  
Level Of Evidence ◽  
Vascular Stenosis ◽  
Ischemic Attack

Ischemic stroke and transient ischemic attack (TIA) are the most common cerebrovascular disorder and leading cause of death in China. The Effective secondary prevention is the vital strategy for reducing stroke recurrence. The aim of this guideline is to provide the most updated evidence-based recommendation to clinical physicians from the prior version. Control of risk factors, intervention for vascular stenosis/occlusion, antithrombotic therapy for cardioembolism, and antiplatelet therapy for noncardioembolic stroke are all recommended, and the prevention of recurrent stroke in a variety of uncommon causes and subtype provided as well. We modified the level of evidence and recommendation according to part of results from domestic RCT in order to facility the clinical practice.

scholarly journals Cerebral Microbleeds and Early Recurrent Stroke After Transient Ischemic Attack

2015 ◽  
Vol 72 (3) ◽  
pp. 301 ◽  
Author(s):  
Jae-Sung Lim ◽  
Keun-Sik Hong ◽  
Gyeong-Moon Kim ◽  
Oh Young Bang ◽  
Hee-Joon Bae ◽  
...  
Keyword(s):  
Transient Ischemic Attack ◽  
Recurrent Stroke ◽  
Cerebral Microbleeds ◽  
Ischemic Attack

Abstract 41: Prognostic Value of Perfusion MRI in Patients with Transient Ischemic Attack or Minor Stroke

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Joon Hwa Lee ◽  
Hyunjin Jo ◽  
Jihoon Cha ◽  
Woo-Keun Seo ◽  
Oh Young Bang ◽  
...  
Keyword(s):  
Cardiovascular Event ◽  
Transient Ischemic Attack ◽  
Recurrent Stroke ◽  
Perfusion Mri ◽  
Minor Stroke ◽  
Secondary Outcome ◽  
Stroke Recurrence ◽  
Composite Outcome ◽  
Stroke Patients ◽  
Ischemic Attack

Background and purpose: We aimed to investigate the role of perfusion MRI parameters (TTP: time to peak, CBF: cerebral blood flow, CBV: cerebral blood volume) as a prognostic factor for the risk of stroke recurrence or cardiovascular outcome in patients with transient ischemic attack (TIA) or minor stroke. Methods: We retrospectively reviewed TIA or minor stroke patients who underwent our stroke MRI protocol (DWI, perfusion MRI, and MRA) in a consecutively collected stroke registry. Primary outcome was nonfatal stroke recurrence and secondary outcome was cardiovascular composite outcome. Multivariate analysis was used to examine the association of perfusion MRI parameters and angiographic findings with the risk of stroke recurrence and cardiovascular event. Results: Of the 326 patients who met inclusion criteria, we identified 15(4.6%) nonfatal strokes and 25(7.7%) cardiovascular composite events during the first 1 year after the index TIA or minor stroke. The presence of regional delayed perfusion on TTP maps (p=0.002) and regional hyperperfusion on CBV maps (p<0.001) were associated with recurrent stroke. In MRA images, concomitant stenosis of the intracranial arteries and/or extracranial carotid arteries was associated with cardiovascular events (p=0.009). Using multivariate cox proportional hazard analysis, presence of regional hyperperfusion on CBV remained an independent predictor of recurrent stroke (HR 10.82, 95% CI 4.19-38.67, p<0.001) and cardiovascular event (HR 6.30, 95% CI 2.67-18.25, p<0.001). The AUC of the CBV maps was also greater than other parameters for the prediction of stroke recurrence (AUC=0.701, 95% CI 0.54-0.86) and cardiovascular composite outcome (AUC=0.628, 95% CI 0.50-0.76). Conclusions: Increased CBV on perfusion MRI, representing the hemodynamic status of postischemic hyperperfusion, could be more useful than other perfusion parameters in predicting poor prognosis of TIA or minor stroke patients.

Obstructed Flow

2016 ◽  
Author(s):  
Ji Y. Chong ◽  
Michael P. Lerario
Keyword(s):  
Carotid Endarterectomy ◽  
Carotid Stenosis ◽  
Transient Ischemic Attack ◽  
Recurrent Stroke ◽  
Early Period ◽  
Carotid Stenting ◽  
Symptomatic Carotid ◽  
Symptomatic Carotid Stenosis ◽  
Ischemic Attack

Patients with symptomatic carotid stenosis benefit from revascularization. The risk of recurrent stroke is highest during the early period after a transient ischemic attack or stroke. Carotid endarterectomy and carotid stenting are options for treatment and should be considered within the first 2 weeks if feasible.

scholarly journals Recurrent Stroke was Associated with Poor Quality of Life in Patients with Transient Ischemic Attack or Minor Stroke: Finding from the CHANCE Trial

2014 ◽  
Vol 20 (12) ◽  
pp. 1029-1035 ◽  
Author(s):  
Yi-Long Wang ◽  
Yue-Song Pan ◽  
Xing-Quan Zhao ◽  
David Wang ◽  
S Claiborne Johnston ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Transient Ischemic Attack ◽  
Recurrent Stroke ◽  
Poor Quality ◽  
Minor Stroke ◽  
Ischemic Attack

scholarly journals Validation of the Essen Stroke Risk Score and the Stroke Prognosis Instrument II in Chinese Patients

Stroke ◽  
2011 ◽  
Vol 42 (12) ◽  
pp. 3619-3620 ◽  
Author(s):  
Xia Meng ◽  
Yilong Wang ◽  
Xingquan Zhao ◽  
Chunxue Wang ◽  
Hao Li ◽  
...  
Keyword(s):  
Risk Score ◽  
Transient Ischemic Attack ◽  
Stroke Risk ◽  
Predictive Accuracy ◽  
Recurrent Stroke ◽  
Chinese Patients ◽  
Vascular Events ◽  
Ischemic Attack ◽  
Event Rates ◽  
Prognostic Instrument

Background and Purpose— Little was known about the predictive accuracy of the Essen Stroke Risk Score and the Stroke Prognostic Instrument II in Chinese patients with stroke. Methods— We evaluated the predictive accuracy of both Essen Stroke Risk Score and Stroke Prognostic Instrument II scores for both recurrent stroke and combined vascular events using data from a prospective cohort of 11 384 patients with acute ischemic stroke and transient ischemic attack admitted to 132 urban hospitals throughout China. Results— The cumulative 1-year event rates were 16% (95% CI, 15%–16%) for recurrent stroke and 18% (95% CI, 18%–19%) for combined vascular events. Both event rates were significantly higher in patients with transient ischemic attack and increased significantly from lower to higher Essen Stroke Risk Score and Stroke Prognostic Instrument II categories. Essen Stroke Risk Score and Stroke Prognostic Instrument II had similar predictive accuracies for each study outcome. Conclusions— In Chinese patients with ischemic stroke or transient ischemic attack, both Essen Stroke Risk Score and Stroke Prognostic Instrument II scores are equally able to stratify the risk of recurrent stroke and combined vascular events.

scholarly journals Perception of Recurrent Stroke Risk among Black, White and Hispanic Ischemic Stroke and Transient Ischemic Attack Survivors: The SWIFT Study

2011 ◽  
Vol 37 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Bernadette Boden-Albala ◽  
Heather Carman ◽  
Megan Moran ◽  
Margaret Doyle ◽  
Myunghee C. Paik
Keyword(s):  
Ischemic Stroke ◽  
Transient Ischemic Attack ◽  
Stroke Risk ◽  
Recurrent Stroke ◽  
Ischemic Attack
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