The Relationship Between Neutrophil Lymphocyte Ratio With Urinary Protein Albumin Excretion in Newly Diagnosed Patients With Type 2 Diabetes

2014 ◽  
Vol 347 (3) ◽  
pp. 217-220 ◽  
Author(s):  
Baris Afsar
Keyword(s):  
Type 2 Diabetes ◽  
Urinary Protein ◽  
Newly Diagnosed ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Albumin Excretion ◽  
The Relationship

Correlation Analysis of Carotid Plaque in Young Patients With Newly Diagnosed Type 2 Diabetes and Platelet to Lymphocyte Ratio (PLR) and Neutrophil-Lymphocyte Ratio (NLR)

2021 ◽  
Author(s):  
Huijun Wen ◽  
Hai Yu
Keyword(s):  
Type 2 Diabetes ◽  
Young Patients ◽  
Newly Diagnosed ◽  
Platelet To Lymphocyte Ratio ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Grade Ii ◽  
The Relationship ◽  
Grade Iii

Abstract Background PLR and NLR had been reported that they may be related to carotid atherosclerotic. The relationship between PLR, NLR and carotid atherosclerotic plaque in young patients with newly diagnosed type 2 diabetes had not been clinically reported. Objectives To analyzed the relationship between platelet to lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and carotid plaques in young patients with newly diagnosed type 2 diabetes. Methods The patients were divided into intima-media thickening (IMT)group and plaque group. The plaque group was divided into grade I, grade II and grade III groups. The counts of platelets, neutrophils, and lymphocytes were determined. Results The diagnostic effect of PLR and NLR was evaluated by Receiver Operating Characteristic Curve (ROC) and areas under the curve (AUC). The PLR and NLR values in observation group were higher than control group; two values in plaque group were higher than IMT group. The two values in t grade III plaque group were higher than in grade II. The two values in grade II plaque group were higher than grade I plaque group. The ROC of PLR and NLR were 0.722 and 0.653, the AUC of PLR and NLR were 111.086 and 2.240. PLR yielded a sensitivity of 0.789 and a specificity of 0.612. Conclusion NLR yielded a sensitivity of 0.809 and a specificity of 0.511. The PLR and NLR may be related to carotid inflammation in patients and positively correlated with carotid plaque.

scholarly journals Neutrophil-lymphocyte ratio correlates with limited joint mobility of hand in patients with type 2 diabetes

2018 ◽  
Vol 65 (10) ◽  
pp. 1011-1017
Author(s):  
Yusuke Mineoka ◽  
Michiyo Ishii ◽  
Yoshitaka Hashimoto ◽  
Naoto Nakamura ◽  
Yasukazu Katsumi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Joint Mobility ◽  
Limited Joint Mobility ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Can hematological parameters in type 2 diabetes predict microvascular complication development?

2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Erhan Onalan ◽  
Nevzat Gozel ◽  
Emir Donder
Keyword(s):  
Type 2 Diabetes ◽  
Microvascular Complications ◽  
Hematological Parameters ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
The Mean ◽  
The Difference

Objective: To examine potential associations between neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, mean platelet volume (MPV), HbA1c and microvascular complications in diabetic patients from a cost-effectiveness perspective. Methods: One hundred patients with type 2 diabetes attending our outpatient unit between May 2018 and October 2018 were included, and 100 healthy individuals served as the control group. A retrospective file search was performed to collect information on hemoglobin, mean platelet volume (MPV), glycosylated haemoglobin (HbA1c), hematocrit (Hct), neutrophil and lymphocyte count, neutrophil/lymphocyte ratio (NLR), platelets (Plt), platelet/lymphocyte ratio (PLR), and microvascular complications (neuropathy, retinopathy, nephropathy). Results: Demographic and laboratory data were retrospectively controlled between diabetes (n=100) and healthy control (n=100) groups. The mean age in diabetic patients and healthy controls was 56.34 and 36.68 years, respectively. The mean NLR in diabetics and healthy controls was 2.48 and 2.11, the difference in NLR being significant (p=0.002). MPV in diabetics and controls was 8.54 and 8.53, respectively, and the difference was not significant (p=0.93). PLR was also similar, i.e. 149.7 and 145.3 in diabetics and healthy controls (p=0.067). With respect to microvascular complications, retinopathy was found to be significantly associated with MPV and NLR (p=0.015, and p=0.051), and nephropathy showed a significant association with NLR (p=0.027) among diabetics. In contrast with the two other microvascular complications, no significant association between neuropathy and NLR could be detected, while PLR and neuropathy was significantly associated (p=0.003). Conclusion: Microvascular complications may be associated with certain hematologic parameters, as suggested by comparisons both between diabetics and healthy individuals and within the group of diabetic individuals. We believe that hematologic parameters such as hematocrit, MPV, NLR, and PLR, which can be obtained through a simple complete blood count, may be utilized as cost-effective predictors of diabetic microvascular complications. Further prospective studies with larger sample size are required to better delineate these associations. doi: https://doi.org/10.12669/pjms.35.6.1150 How to cite this:Onalan E, Gozel N, Donder E. Can hematological parameters in type 2 diabetes predict microvascular complication development? Pak J Med Sci. 2019;35(6):1511-1515. doi: https://doi.org/10.12669/pjms.35.6.1150 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Relationship between neutrophil/lymphocyte ratio and epicardial fat tissue thickness in patients with newly diagnosed hypertension

2018 ◽  
Vol 46 (3) ◽  
pp. 940-950 ◽  
Author(s):  
Mehmet Ali Derya ◽  
Vahit Demir ◽  
Huseyin Ede
Keyword(s):  
Blood Pressure ◽  
Healthy Subjects ◽  
Control Group ◽  
Newly Diagnosed ◽  
Fat Tissue ◽  
Tissue Thickness ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Epicardial Fat Tissue ◽  
The Relationship

Objective Epicardial fat tissue thickness (EFT) and the neutrophil/lymphocyte ratio (NLR) are associated with atherosclerosis. Few studies have focused on the relationship between these parameters in patients with newly diagnosed hypertension. In this study, we examined the relationship between EFT and the NLR in patients with newly diagnosed hypertension detected by 24-hour ambulatory blood pressure monitoring (ABPM). Methods Eighty consecutive patients without chronic illness who were diagnosed with hypertension according to ABPM results and 80 otherwise healthy subjects were enrolled in the study. EFT of each participant was measured echocardiographically. The C-reactive protein (CRP) concentration and NLR were measured from venous blood samples. Results The 24-hour average systolic blood pressure was significantly higher in the hypertension group than in the control group (143±17 vs. 117±7 mmHg, respectively). There were no significant differences in age, sex, or body mass index between the two groups. EFT, the NLR, and the CRP concentration were significantly higher in the hypertension group than control group. Additionally, a significantly positive correlation between EFT and the NLR was found in both the control group and hypertension group. Conclusion A higher EFT and NLR were detected in patients with newly diagnosed hypertension than in healthy subjects.

scholarly journals Comparison of Acarbose and Metformin on Albumin Excretion in Patients With Newly Diagnosed Type 2 Diabetes

Medicine ◽  
2016 ◽  
Vol 95 (14) ◽  
pp. e3247 ◽  
Author(s):  
Qingrong Pan ◽  
Yuan Xu ◽  
Ning Yang ◽  
Xia Gao ◽  
Jia Liu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Newly Diagnosed ◽  
Albumin Excretion
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