Comparison of Existing Clinical Scoring Systems in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP. Ranson did not have significant advantage in predicting severity and prognosis of HLAP compared to other three scoring systems. APACHE II was the best in predicting severity of HLAP, but it had shortcoming in predicting local complications. MCTSI had outstanding performance in predicting local complications, but it was poor in predicting severity and mortality. BISAP score had high accuracy in assessment of severity, local complications, and mortality of HLAP, but the accuracy still needs to be improved in the future.

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Applicability of clinical scoring systems after transarterial chemoembolisation in the bridging to transplant setting

Zeitschrift für Gastroenterologie ◽

10.1055/s-0038-1668950 ◽

2018 ◽

Vol 56 (08) ◽

pp. e312-e313

Author(s):

I Mohr ◽

M Vogeler ◽

J Pfeiffenberger ◽

D Sprengel ◽

M Klauss ◽

...

Keyword(s):

Scoring Systems ◽

Transarterial Chemoembolisation ◽

Clinical Scoring ◽

Bridging To Transplant

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Clinical scoring systems fare poorly among elderly patients in diagnosing primary hypothyroidism

Endocrine Abstracts ◽

10.1530/endoabs.70.aep988 ◽

2020 ◽

Author(s):

Varun Singla ◽

Mary John ◽

Jacob Jubbin Jagan

Keyword(s):

Elderly Patients ◽

Scoring Systems ◽

Primary Hypothyroidism ◽

Clinical Scoring

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Haemoconcentration as a predictor of severity in acute pancreatitis

Journal of Kathmandu Medical College ◽

10.3126/jkmc.v4i1.15020 ◽

2016 ◽

Vol 4 (1) ◽

pp. 3-7

Author(s):

Tanka Prasad Bohara ◽

Dimindra Karki ◽

Anuj Parajuli ◽

Shail Rupakheti ◽

Mukund Raj Joshi

Keyword(s):

Acute Pancreatitis ◽

Pearson Correlation ◽

Characteristic Curve ◽

Scoring Systems ◽

Cost Effective ◽

Receiver Operator Characteristic Curve ◽

First Episode ◽

P Value ◽

Receiver Operator Characteristic ◽

Chi Square

Background: Acute pancreatitis is usually a mild and self-limiting disease. About 25 % of patients have severe episode with mortality up to 30%. Early identification of these patients has potential advantages of aggressive treatment at intensive care unit or transfer to higher centre. Several scoring systems are available to predict severity of acute pancreatitis but are cumbersome, take 24 to 48 hours and are dependent on tests that are not universally available. Haematocrit has been used as a predictor of severity of acute pancreatitis but some have doubted its role.Objectives: To study the significance of haematocrit in prediction of severity of acute pancreatitis.Methods: Patients admitted with first episode of acute pancreatitis from February 2014 to July 2014 were included. Haematocrit at admission and 24 hours of admission were compared with severity of acute pancreatitis. Mean, analysis of variance, chi square, pearson correlation and receiver operator characteristic curve were used for statistical analysis.Results: Thirty one patients were included in the study with 16 (51.61%) male and 15 (48.4%) female. Haematocrit at 24 hours of admission was higher in severe acute pancreatitis (P value 0.003). Both haematocrit at admission and at 24 hours had positive correlation with severity of acute pancreatitis (r: 0.387; P value 0.031 and r: 0.584; P value 0.001) respectively.Area under receiver operator characteristic curve for haematocrit at admission and 24 hours were 0.713 (P value 0.175, 95% CI 0.536 - 0.889) and 0.917 (P value 0.008, 95% CI 0.813 – 1.00) respectively.Conclusion: Haematocrit is a simple, cost effective and widely available test and can predict severity of acute pancreatitis.Journal of Kathmandu Medical College, Vol. 4(1) 2015, 3-7

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Relationship between sensation seeking, alcohol problems and bulimic symptoms: a community-based, longitudinal study

Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity ◽

10.1007/s40519-021-01193-6 ◽

2021 ◽

Author(s):

Leon Hirvelä ◽

Pyry N. Sipilä ◽

Anna Keski-Rahkonen

Keyword(s):

Sensation Seeking ◽

Early Adulthood ◽

Scoring Systems ◽

Population Level ◽

Alcohol Problems ◽

Community Based ◽

Level Of Evidence ◽

Bulimic Symptoms ◽

Clinical Scoring ◽

Sensation Seeking Scale

Abstract Purpose The association of bulimic symptoms with sensation seeking is uncertain; however, both behaviors have been linked to alcohol problems. We assessed in a longitudinal, community-based setting whether sensation seeking in adolescence is associated with bulimic symptoms in early adulthood, also accounting for alcohol problems. Methods Finnish men (N = 2000) and women (N = 2467) born between 1974–1979 completed Zuckerman’s sensation seeking scale (SSS) at age 18. Alcohol problems (Malmö-modified Michigan alcoholism screening test (Mm-MAST) and bulimic symptoms [eating disorder inventory-2, bulimia subscale (EDI-Bulimia), population and clinical scoring systems] were defined at age 22–27. We examined relationships between SSS, Mm-MAST, and EDI-Bulimia using Pearson’s correlation coefficient (r) and linear regression. Results Alcohol problems were moderately correlated with sensation seeking and bulimic symptoms (population scoring) among women and men (r = 0.21–0.31). The correlation between sensation seeking and bulimic symptoms (population scoring) was weak among men (r = 0.06, p = 0.006) and even weaker and non-significant among women (r = 0.03, p = 0.214). Adjustment for alcohol problems removed the association between sensation seeking and bulimic symptoms among men. Furthermore, there were no significant correlations between sensation seeking and bulimic symptoms when assessing EDI-Bulimia clinical scoring. Conclusion Sensation seeking and bulimic symptoms were not associated among women. The association between sensation seeking and bulimic symptoms among men was entirely attributable to increased alcohol problems among those with higher sensation seeking. While this association may be important on the population level, its clinical significance may be minor. Level of evidence Level III, well-designed cohort study.

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Accuracy of conventional and novel scoring systems in predicting severity and outcomes of acute pancreatitis: a retrospective study

Lipids in Health and Disease ◽

10.1186/s12944-021-01470-4 ◽

2021 ◽

Vol 20 (1) ◽

Author(s):

Qing Wu ◽

Jie Wang ◽

Mengbin Qin ◽

Huiying Yang ◽

Zhihai Liang ◽

...

Keyword(s):

Acute Pancreatitis ◽

Organ Failure ◽

Scoring System ◽

Characteristic Curve ◽

Failure Prediction ◽

Scoring Systems ◽

Mortality Prediction ◽

Severity Prediction ◽

Index Of Severity ◽

Glasgow Score

Abstract Background Recently, several novel scoring systems have been developed to evaluate the severity and outcomes of acute pancreatitis. This study aimed to compare the effectiveness of novel and conventional scoring systems in predicting the severity and outcomes of acute pancreatitis. Methods Patients treated between January 2003 and August 2020 were reviewed. The Ranson score (RS), Glasgow score (GS), bedside index of severity in acute pancreatitis (BISAP), pancreatic activity scoring system (PASS), and Chinese simple scoring system (CSSS) were determined within 48 h after admission. Multivariate logistic regression was used for severity, mortality, and organ failure prediction. Optimum cutoffs were identified using receiver operating characteristic curve analysis. Results A total of 1848 patients were included. The areas under the curve (AUCs) of RS, GS, BISAP, PASS, and CSSS for severity prediction were 0.861, 0.865, 0.829, 0.778, and 0.816, respectively. The corresponding AUCs for mortality prediction were 0.693, 0.736, 0.789, 0.858, and 0.759. The corresponding AUCs for acute respiratory distress syndrome prediction were 0.745, 0.784, 0.834, 0.936, and 0.820. Finally, the corresponding AUCs for acute renal failure prediction were 0.707, 0.734, 0.781, 0.868, and 0.816. Conclusions RS and GS predicted severity better than they predicted mortality and organ failure, while PASS predicted mortality and organ failure better. BISAP and CSSS performed equally well in severity and outcome predictions.

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