scholarly journals Significant partial response of metastatic intra-abdominal and pelvic round cell liposarcoma to a small-molecule VEGFR-2 tyrosine kinase inhibitor apatinib

Medicine ◽  
2016 ◽  
Vol 95 (31) ◽  
pp. e4368 ◽  
Author(s):  
Min Dong ◽  
Jingwang Bi ◽  
Xiaohong Liu ◽  
Baocheng Wang ◽  
Jun Wang
Keyword(s):  
Partial Response ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Small Molecule ◽  
Kinase Inhibitor ◽  
Round Cell

scholarly journals Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412

Cancer Cell ◽  
2002 ◽  
Vol 1 (5) ◽  
pp. 433-443 ◽  
Author(s):  
Ellen Weisberg ◽  
Christina Boulton ◽  
Louise M Kelly ◽  
Paul Manley ◽  
Doriano Fabbro ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Small Molecule ◽  
Kinase Inhibitor ◽  
Leukemia Cells

scholarly journals Radioiodinated Small-Molecule Tyrosine Kinase Inhibitor for HER2-Selective SPECT Imaging

2018 ◽  
Vol 59 (9) ◽  
pp. 1386-1391 ◽  
Author(s):  
Longguang Tang ◽  
Chenyu Peng ◽  
Bowen Tang ◽  
Zijing Li ◽  
Xiangyu Wang ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Small Molecule ◽  
Kinase Inhibitor ◽  
Spect Imaging

Optical spectra and conformation pool of tyrosine kinase inhibitor PD153035 using robust quantum mechanical conformation search

2022 ◽  
Author(s):  
Feng Wang ◽  
Vladislav Vasilyev ◽  
Andrew Clayton
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Tyrosine Kinase Inhibitors ◽  
Small Molecule ◽  
Kinase Inhibitors ◽  
Kinase Inhibitor ◽  
Optical Spectra ◽  
Quantum Mechanical ◽  
Small Molecule Drugs ◽  
Significant Class

Tyrosine kinase inhibitors (TKIs) based on the quinazoline-aniline scaffold represent a significant class of small molecule drugs for diseases such as cancer. The present study applies the recently developed robust...

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