scholarly journals Prognostic value of 18F-FET PET/CT in newly diagnosed WHO 2016 high-grade glioma

Medicine ◽  
2020 ◽  
Vol 99 (5) ◽  
pp. e19017 ◽  
Author(s):  
Gurvan Dissaux ◽  
Victor Basse ◽  
Ulrike Schick ◽  
Osman EL Kabbaj ◽  
Benjamin Auberger ◽  
...  
Keyword(s):  
Prognostic Value ◽  
High Grade Glioma ◽  
High Grade ◽  
Newly Diagnosed ◽  
Fet Pet ◽  
Pet Ct

Comparison Between 18F-Dopa and 18F-Fet PET/CT in Patients with Suspicious Recurrent High Grade Glioma: A Literature Review and Our Experience

2019 ◽  
Vol 12 (3) ◽  
pp. 220-228 ◽  
Author(s):  
Laura Evangelista ◽  
Lea Cuppari ◽  
Luisa Bellu ◽  
Daniele Bertin ◽  
Mario Caccese ◽  
...  
Keyword(s):  
Case Series ◽  
High Grade Glioma ◽  
High Grade ◽  
True Negative ◽  
Fet Pet ◽  
Positron Emission ◽  
Pet Ct ◽  
Magnetic Resonance Imaging Mri ◽  
Definition Of ◽  
Sensitivity Specificity

Purpose: The aims of the present study were to: 1- critically assess the utility of L-3,4- dihydroxy-6-18Ffluoro-phenyl-alanine (18F-DOPA) and O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) Positron Emission Tomography (PET)/Computed Tomography (CT) in patients with high grade glioma (HGG) and 2- describe the results of 18F-DOPA and 18F-FET PET/CT in a case series of patients with recurrent HGG. Methods: We searched for studies using the following databases: PubMed, Web of Science and Scopus. The search terms were: glioma OR brain neoplasm and DOPA OR DOPA PET OR DOPA PET/CT and FET OR FET PET OR FET PET/CT. From a mono-institutional database, we retrospectively analyzed the 18F-DOPA and 18F-FET PET/CT of 29 patients (age: 56 ± 12 years) with suspicious for recurrent HGG. All patients underwent 18F-DOPA or 18F-FET PET/CT for a multidisciplinary decision. The final definition of recurrence was made by magnetic resonance imaging (MRI) and/or multidisciplinary decision, mainly based on the clinical data. Results: Fifty-one articles were found, of which 49 were discarded, therefore 2 studies were finally selected. In both the studies, 18F-DOPA and 18F-FET as exchangeable in clinical practice particularly for HGG patients. From our institutional experience, in 29 patients, we found that sensitivity, specificity and accuracy of 18F-DOPA PET/CT in HGG were 100% (95% confidence interval- 95%CI - 81-100%), 63% (95%CI: 39-82%) and 62% (95%CI: 39-81%), respectively. 18F-FET PET/CT was true positive in 4 and true negative in 4 patients. Sensitivity, specificity and accuracy for 18F-FET PET/CT in HGG were 100%. Conclusion: 18F-DOPA and 18F-FET PET/CT have a similar diagnostic accuracy in patients with recurrent HGG. However, 18F-DOPA PET/CT could be affected by inflammation conditions (false positive) that can alter the final results. Large comparative trials are warranted in order to better understand the utility of 18F-DOPA or 18F-FET PET/CT in patients with HGG.

scholarly journals Prognostic Significance of Dynamic 18F-FET PET in Newly Diagnosed Astrocytic High-Grade Glioma

2014 ◽  
Vol 56 (1) ◽  
pp. 9-15 ◽  
Author(s):  
N. L. Jansen ◽  
B. Suchorska ◽  
V. Wenter ◽  
C. Schmid-Tannwald ◽  
A. Todica ◽  
...  
Keyword(s):  
Prognostic Significance ◽  
High Grade Glioma ◽  
High Grade ◽  
Newly Diagnosed ◽  
Fet Pet

Prognostic value of 18F-FET PET imaging in re-irradiation of high-grade glioma: Results of a phase I clinical trial

2016 ◽  
Vol 121 (1) ◽  
pp. 132-137 ◽  
Author(s):  
Soren Moller ◽  
Ian Law ◽  
Per Munck af Rosenschold ◽  
Junia Costa ◽  
Hans Skovgaard Poulsen ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Phase I ◽  
Pet Imaging ◽  
Prognostic Value ◽  
High Grade Glioma ◽  
Phase I Clinical Trial ◽  
High Grade ◽  
Fet Pet

18F-FET PET prior to recurrent high-grade glioma re-irradiation—additional prognostic value of dynamic time-to-peak analysis and early static summation images?

2017 ◽  
Vol 132 (2) ◽  
pp. 277-286 ◽  
Author(s):  
Daniel F. Fleischmann ◽  
Marcus Unterrainer ◽  
Peter Bartenstein ◽  
Claus Belka ◽  
Nathalie L. Albert ◽  
...  
Keyword(s):  
Prognostic Value ◽  
High Grade Glioma ◽  
High Grade ◽  
Fet Pet ◽  
Time To Peak ◽  
Dynamic Time

scholarly journals PO-0650: Prognostic value of minimal time to peak in dynamic 18F-FET-PET for high-grade glioma re-irradiation

2016 ◽  
Vol 119 ◽  
pp. S304
Author(s):  
D.F. Fleischmann ◽  
M. Unterrainer ◽  
P. Bartenstein ◽  
C. Belka ◽  
N.L. Albert ◽  
...  
Keyword(s):  
Prognostic Value ◽  
High Grade Glioma ◽  
High Grade ◽  
Fet Pet ◽  
Time To Peak ◽  
Minimal Time

Direct medical costs of treatment in newly-diagnosed high-grade glioma among commercially insured US patients

2017 ◽  
Vol 20 (12) ◽  
pp. 1237-1243 ◽  
Author(s):  
Shan Jiang ◽  
Kala Hill ◽  
Dipen Patel ◽  
A. Reginald Waldeck ◽  
Marc Botteman ◽  
...  
Keyword(s):  
High Grade Glioma ◽  
Medical Costs ◽  
High Grade ◽  
Newly Diagnosed ◽  
Direct Medical Costs ◽  
Costs Of Treatment
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