Treatment of Castration-Resistant Prostate Cancer: Updates on Therapeutics Targeting the Androgen Receptor Signaling Pathway

American Journal of Therapeutics ◽

10.1097/mjt.0b013e3181c6c0b2 ◽

2010 ◽

Vol 17 (2) ◽

pp. 176-181 ◽

Author(s):

Wenhui Zhu ◽

David S Zhu ◽

Ravi A Madan ◽

James L Gulley ◽

William D Figg ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Signaling Pathway ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant ◽

Receptor Signaling Pathway

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The role of TXNDC5 in castration-resistant prostate cancer—involvement of androgen receptor signaling pathway

Oncogene ◽

10.1038/onc.2014.401 ◽

2014 ◽

Vol 34 (36) ◽

pp. 4735-4745 ◽

Author(s):

L Wang ◽

G Song ◽

X Chang ◽

W Tan ◽

J Pan ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Signaling Pathway ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant ◽

Receptor Signaling Pathway

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Combination of phospholipase Cε knockdown with GANT61 sensitizes castration‑resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway

Oncology Reports ◽

10.3892/or.2019.7054 ◽

2019 ◽

Author(s):

Wei Sun ◽

Luo Li ◽

Zhongbo Du ◽

Zhen Quan ◽

Mengjuan Yuan ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Cells ◽

Signaling Pathway ◽

Castration Resistant Prostate Cancer ◽

Prostate Cancer Cells ◽

Androgen Receptor Signaling ◽

Castration Resistant ◽

Receptor Signaling Pathway ◽

Phospholipase Cε

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Abstract 2509:RB1-loss in castration-resistant prostate cancer reprograms androgen receptor signaling and confers vulnerability to LSD1 inhibition

10.1158/1538-7445.am2021-2509 ◽

2021 ◽

Author(s):

Wanting Han ◽

Mingyu Liu ◽

Dong Han ◽

Muqing Li ◽

Anthia A. Toure ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant

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Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

Frontiers in Oncology ◽

10.3389/fonc.2020.580617 ◽

2020 ◽

Vol 10 ◽

Author(s):

Takuma Uo ◽

Cynthia C. Sprenger ◽

Stephen R. Plymate

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Receptor Signaling ◽

Cellular Plasticity ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant

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Targeting Oct1 genomic function inhibits androgen receptor signaling and castration-resistant prostate cancer growth

Oncogene ◽

10.1038/onc.2016.171 ◽

2016 ◽

Vol 35 (49) ◽

pp. 6350-6358 ◽

Author(s):

D Obinata ◽

K Takayama ◽

K Fujiwara ◽

T Suzuki ◽

S Tsutsumi ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Growth ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant ◽

Genomic Function

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A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer

Theranostics ◽

10.7150/thno.34485 ◽

2019 ◽

Vol 9 (10) ◽

pp. 2812-2826 ◽

Author(s):

Yu Jen Jan ◽

Junhee Yoon ◽

Jie-Fu Chen ◽

Pai-Chi Teng ◽

Nu Yao ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Circulating Tumor Cell ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant

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Correction to Supporting Information for Zadra et al., Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.2012767117 ◽

2020 ◽

Vol 117 (31) ◽

pp. 18893-18893

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

De Novo ◽

De Novo Lipogenesis ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant

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New Strategies in Metastatic Prostate Cancer: Targeting the Androgen Receptor Signaling Pathway

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-10-0567 ◽

2011 ◽

Vol 17 (7) ◽

pp. 1649-1657 ◽

Author(s):

Gerhardt Attard ◽

Juliet Richards ◽

Johann S. de Bono

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Signaling Pathway ◽

Metastatic Prostate Cancer ◽

Cancer Targeting ◽

Receptor Signaling ◽

Androgen Receptor Signaling ◽

Receptor Signaling Pathway ◽

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Growth and migration of LNCaP prostate cancer cells are promoted by triclosan and benzophenone-1 via an androgen receptor signaling pathway

Environmental Toxicology and Pharmacology ◽

10.1016/j.etap.2015.01.003 ◽

2015 ◽

Vol 39 (2) ◽

pp. 568-576 ◽

Author(s):

Seung-Hee Kim ◽

Kyung-A Hwang ◽

Soon-Mi Shim ◽

Kyung-Chul Choi

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Cells ◽

Signaling Pathway ◽

Receptor Signaling ◽

Prostate Cancer Cells ◽

Androgen Receptor Signaling ◽

Receptor Signaling Pathway ◽

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Combination treatment with docetaxel and histone deacetylase inhibitors downregulates androgen receptor signaling in castration-resistant prostate cancer

Investigational New Drugs ◽

10.1007/s10637-017-0529-x ◽

2017 ◽

Vol 36 (2) ◽

pp. 195-205 ◽

Author(s):

Sang Eun Park ◽

Ha-Gyeong Kim ◽

Dong Eun Kim ◽

Yoo Jung Jung ◽

Yunlim Kim ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Histone Deacetylase ◽

Combination Treatment ◽

Histone Deacetylase Inhibitors ◽

Receptor Signaling ◽

Castration Resistant Prostate Cancer ◽

Androgen Receptor Signaling ◽

Castration Resistant

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