Female Sex, Bilateral Disease, Age Below 3 Years, and Apprehension for Enucleation Contribute to Treatment Abandonment in Retinoblastoma

2017 ◽  
Vol 39 (5) ◽  
pp. e249-e253 ◽  
Author(s):  
Anish Bhargav ◽  
Usha Singh ◽  
Amita Trehan ◽  
Zoramathara Zadeng ◽  
Deepak Bansal
Author(s):  
S. Karkare ◽  
J. Gilloteaux ◽  
T. R. Kelly

Approximately 1 million people in the United States alone develop gallstones each year. The incidence is higher in women than in men and the ratio being 4 ≥ 1. A correlation has also been suggested between oral contraceptives and cholelithiasis. In addition, postmenopausal or cancer estrogen therapy has been reported to be a factor responsible for gallstone formation. Female sex hormone receptors have been detected not only in the gallbladder musculature, but also in its epithelium. As a follow up to experiments effectuated in the male and the ovariectomized Syrian hamster, this report shows that, a combination of a low cholesterol diet with female sex steroid treatment contributes to the formation of gallstone-like deposits, while modifying the surface epithelium morphology. Syrian hamsters (F1B strain, BioBreeders, Watertown MA) were housed under 12h light: 12 h dark cycle, at 20 °C, fed Purina chow and water ad libitum. Several duration/treatment groups were studied, but this report will focus on data obtained with the group injected weekly with estradiol valerate (E weekly, s.c. 8-10 μg/100 g.b.w., in corn oil) and with i.m. medroxyprogesterone acetate (DepoProvera Upjohn Co., Kalamazoo, MI; 8-10 mg/100 g.b.w.) for a 3-month period. Other parameters (blood and bile) were also studied but not reported here.


2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.


2010 ◽  
Vol 222 (S 01) ◽  
Author(s):  
M Laube ◽  
E Küppers ◽  
U Thome

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
G. Färber ◽  
M. Zacher ◽  
T. Doenst ◽  
T. Sandhaus ◽  
M. Diab ◽  
...  

2012 ◽  
Vol 41 (2) ◽  
pp. 22-27
Author(s):  
Sissel Undheim

The description of Christ as a virgin, 'Christus virgo', does occur at rare occasions in Early Christian and late antique texts. Considering that 'virgo' was a term that most commonly described the sexual and moral status of a member of the female sex, such representations of Christ as a virgin may exemplify some of the complex negotiations over gender, salvation, sanctity and Christology that we find in the writings of the Church fathers. The article provides some suggestions as to how we can understand the notion of the virgin Christ within the context of early Christian and late antique theological debates on the one hand, and in light of the growing interest in sacred virginity on the other.


Author(s):  
James H. Clark ◽  
Ernest J. Peck
Keyword(s):  

2018 ◽  
Author(s):  
S.V. Kuzmin ◽  
A.V. Medvedev ◽  
A.F. Bukharov

Из обширного исходного материала выделено три половых типа кабачка. Для дифференциации использовано два показателя степени сексуализации: начало образования женских цветков и их количество. Усилению проявления женского типа цветения способствуют сложные скрещивания. Это обеспечивает объединение в одном генотипе различных наследственных факторов. Летний посев значительно снижает выраженность женского пола и позволяет выделить линии с гарантированно высокой экспрессией признака, имеющих от 25 % до 90 % женских растений.From the extensive source material, three sex types of squash are distinguished. For differentiation, two indicators of the degree of sexualization were used: the beginning of the formation of female flowers and their number. Enhancing the manifestation of the female type of flowering is facilitated by complex crossings. This ensures the unification of different hereditary factors in one genotype. Summer sowing significantly reduces the expression of the female sex and makes it possible to isolate lines with a guaranteed high expression of the trait having from 25% to 90% of female plants.


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