The Relationship between Circulating Leptin and Plasma Female Sex Hormone Levels in Physically Active Regularly Menstruating Premenopausal Women with Ovulatory and Anovulatory Menstrual Cycles

2008 ◽  
Vol 12 (2) ◽  
pp. 25-30
Author(s):  
Anna Kęska ◽  
Elżbieta Skierska ◽  
Grażyna Lutosławska ◽  
Joanna Tkaczyk
Keyword(s):  
Premenopausal Women ◽  
Sex Hormone ◽  
Physically Active ◽  
Menstrual Cycles ◽  
Hormone Levels ◽  
Female Sex ◽  
The Relationship

scholarly journals Bioavailable testosterone is associated with symptoms of depression in adult men

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052094171
Author(s):  
Zhongbao Chen ◽  
Xubo Shen ◽  
Kunming Tian ◽  
Yijun Liu ◽  
Shimin Xiong ◽  
...  
Keyword(s):  
Depressive Symptom ◽  
Serum Testosterone ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Levels ◽  
Adult Men ◽  
Depressed Group ◽  
The Mean ◽  
Symptom Group ◽  
The Relationship

Objective This study aimed to determine the relationship between serum testosterone levels and depressive symptoms in an adult male population. Methods We conducted a cross-sectional study of 1166 male participants from Zunyi, Guizhou, China. Each participant completed a questionnaire, a brief clinical exam, and had a fasting blood sample taken. We measured serum testosterone, sex hormone-binding globulin, and luteinizing hormone levels. Multiple linear regression was used to evaluate the effect of demographic factors on the relationship between the depressive symptom score and serum sex hormone levels. Results Mean testosterone, sex hormone-binding globulin, and luteinizing hormone levels were significantly higher in the depressive symptom group than in the non-depressed group. The mean calculated free serum testosterone level and free testosterone index (FTI) were significantly lower in the depressive symptom group than in the non-depressed group. Additionally, the mean FTI was significantly negatively correlated with the Beck Depression Inventory scale score in the multiple linear regression model (95% confidence interval: −3.274 to −0.406). Conclusions Decreased bioactive testosterone levels might be a contributing factor of depression in adult men. The FTI could be the most sensitive biomarker reflecting the level of bioavailable testosterone in patients with depression.

scholarly journals The effects of a low-fat/high-fiber diet on sex hormone levels and menstrual cycling in premenopausal women

Cancer ◽  
2003 ◽  
Vol 98 (9) ◽  
pp. 1870-1879 ◽  
Author(s):  
Peter H. Gann ◽  
Robert T. Chatterton ◽  
Susan M. Gapstur ◽  
Kiang Liu ◽  
Daniel Garside ◽  
...  
Keyword(s):  
Premenopausal Women ◽  
Sex Hormone ◽  
Low Fat ◽  
Hormone Levels ◽  
High Fiber ◽  
Fiber Diet ◽  
High Fiber Diet

scholarly journals Lifetime cumulative number of menstrual cycles and serum sex hormone levels in postmenopausal women

2007 ◽  
Vol 108 (1) ◽  
pp. 101-112 ◽  
Author(s):  
Mariana Chavez-MacGregor ◽  
Carla H. van Gils ◽  
Yvonne T. van der Schouw ◽  
Evelyn Monninkhof ◽  
Paulus A. H. van Noord ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Sex Hormone ◽  
Cumulative Number ◽  
Menstrual Cycles ◽  
Hormone Levels

scholarly journals Alcohol and dietary fibre intakes affect circulating sex hormones among premenopausal women

2006 ◽  
Vol 9 (7) ◽  
pp. 875-881 ◽  
Author(s):  
Gertraud Maskarinec ◽  
Yukiko Morimoto ◽  
Yumie Takata ◽  
Suzanne P Murphy ◽  
Frank Z Stanczyk
Keyword(s):  
Breast Cancer ◽  
Dietary Fibre ◽  
Premenopausal Women ◽  
Serum Levels ◽  
Sex Hormone ◽  
Least Square ◽  
Sex Hormone Binding Globulin ◽  
Hormone Levels ◽  
Fibre Intake ◽  
Dietary Fibre Intake

AbstractBackgroundThe association of alcohol and fibre intake with breast cancer may be mediated by circulating sex hormone levels, which are predictors of breast cancer risk.ObjectiveTo evaluate the relationship of alcohol and dietary fibre intake with circulating sex hormone levels among premenopausal women.MethodsA total of 205 premenopausal women completed a validated food-frequency questionnaire at baseline and after 2 years; blood samples taken at the same time were analysed for circulating sex hormone concentrations, including oestrone (E1), oestradiol (E2), free E2, progesterone, androstenedione and sex hormone-binding globulin, by radioimmunoassay. We used mixed models to estimate least-square means of sex hormone concentrations for alcohol intake categories and quartiles of dietary intake.ResultsAfter adjustment for covariates, alcohol consumption was moderately associated with higher circulating oestrogen levels; those who consumed more than one drink per day had 20% higher E2 (Ptrend = 0.07) levels than non-drinkers. In contrast, higher dietary fibre intake was associated with lower serum levels of androstenedione (−8% between the lowest and highest quartiles of intake, Ptrend = 0.06), but not oestrogens. Similarly, consumption of fruits (−12%, Ptrend = 0.03), vegetables (−9%, Ptrend = 0.15) and whole grains (−7%, Ptrend = 0.07) showed inverse associations with androstenedione levels.ConclusionsThe consistency of the observed differences in sex hormone levels associated with alcohol and fibre-rich foods indicates that these nutritional factors may affect sex hormone concentrations and play a role in breast cancer aetiology and prevention.

scholarly journals Adiposity Measures and Menstrual Cycle: Do We Envisage a Relation?

2011 ◽  
Vol 2011 ◽  
pp. 1-5
Author(s):  
Rashmi Sinha ◽  
Anup Kumar Kapoor ◽  
Satwanti Kapoor
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Menstrual Cycle ◽  
Body Mass ◽  
Premenopausal Women ◽  
Impedance Method ◽  
Age At Menarche ◽  
Cycle Duration ◽  
Physically Active ◽  
The Relationship

The study aims to see the relationship between menstrual cycle and adiposity measures in Indian populations as menstrual cycle length has an important bearing on fertility and health of women. 415 premenopausal women in the ages 22–50 years residing in Delhi, India constituted the data. The adiposity was assessed by BMI as well as by using Bio-electric impedance method. The information regarding their physical activity pattern and menstrual cycle was recorded, and age at menarche was obtained through recall method. None of the underweight category women had menstrual cycle of less than 25 days. A decrease in body mass index and an increase in the age at menarche were found with the increase in the duration of menstrual cycle. The majority of women with 25–35 days duration of menstrual cycle in the present study were distributed in all the categories of BMI. Age was found to have no effect on longer cycle. The majority of women were in moderately physically active group and experienced menstrual cycle duration of 25–35 days. It is of utmost importance to identify the effects of moderate levels of physical activity, body mass index, and age at menarche on the menstrual cycle to enable the normal reproductive health of women.

Abstract WP171: Female Sex Hormones and Post Acute Stroke Outcome

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Jessica Ashley ◽  
Charan Singh ◽  
Grace S Griesbach
Keyword(s):  
Sex Hormones ◽  
Independent Living ◽  
Rating Scale ◽  
Sex Hormone ◽  
Protective Effects ◽  
Hormone Levels ◽  
Disability Rating Scale ◽  
Female Sex ◽  
Female Sex Hormones ◽  
Before And After

Introduction: The protective effects of estrogen are widely known following brain injury and waning female sex hormones such as estrogen and prolactin with age are associated with decline in cognitive performance. In this study, we focus on the relationship between female sex hormones and outcome following stroke, specifically how these hormones affect level of disability and responsiveness to rehabilitation following stroke. Methods: Sex hormone levels were evaluated in 54 female stroke survivors with a mean latency of 98.8 days (SEM ± 23.06). Age differences in hormone levels and disability were evaluated according to younger (Y; M=39.3, SEM ± 1.5) and older (O; M=58.4, SEM ± 1.2) age categories. Functional ability was assessed with the Disability Rating Scale (DRS), Independent Living Scale (ILS) and the Mayo-Portland Adaptability Inventory 4 (MPAI). All patients underwent post acute rehabilitation. Results: The Y group had higher levels of estradiol (p<0.05) and prolactin (p<0.05) compared to the O group. Correspondingly, follicle stimulating (FSH) and luteinizing hormones (LH) were higher in the O group (p<0.05). The Y group had lower disability according DRS, ILS activities of daily living (ADL) subscale and MPAII (p<0.05). High levels of prolactin were correlated with better performance in ADL’s (p<0.005). Estradiol correlated with lower disability as measured by MPAI (p<0.005). High values of FSH were associated with lower initiation as assessed by a subscale of the ILS. Analysis of changes in outcome measures before and after rehabilitation showed that both groups benefited equally. Conclusions: Hormones are predictive of levels of disability and independence in ADL’s. Sex hormone levels in post-stroke patients should be considered for prognostication. In spite of hormonal differences both groups benefit from rehabilitation.

scholarly journals Associations between endogenous sex hormone levels and mammographic and bone densities in premenopausal women

2009 ◽  
Vol 20 (7) ◽  
pp. 1039-1053 ◽  
Author(s):  
Mellissa Yong ◽  
Charlotte Atkinson ◽  
Katherine M. Newton ◽  
Erin J. Aiello Bowles ◽  
Frank Z. Stanczyk ◽  
...  
Keyword(s):  
Premenopausal Women ◽  
Sex Hormone ◽  
Hormone Levels

scholarly journals Characteristics of salivary profiles of oestradiol and progesterone in premenopausal women

2005 ◽  
Vol 186 (1) ◽  
pp. 77-84 ◽  
Author(s):  
Robert T Chatterton ◽  
Esnar T Mateo ◽  
Nanjiang Hou ◽  
Alfred W Rademaker ◽  
Simbi Acharya ◽  
...  
Keyword(s):  
Natural Variation ◽  
Premenopausal Women ◽  
Multiple Time ◽  
Menstrual Cycles ◽  
Breast Center ◽  
Multiple Time Points ◽  
The Relationship ◽  
Density Study ◽  
Initial Cycle ◽  
Hormonal Levels

The objective of the study was to characterize salivary sex steroid levels in 56 women undergoing annual mammography who were participating in a breast density study at the Lynn Sage Breast Center of Northwestern Memorial Hospital, and to determine the predictability of the patterns within women. Saliva was collected daily by the women at home for one complete menstrual cycle and then again at approximately 6-month intervals. The occurrence of sporadic anovulatory cycles was identified in 12 subjects, and persistent oestradiol (OE2) elevation in all three cycles without significant progesterone levels occurred in another five subjects. In addition, both OE2 and progesterone were significantly lower in initial menstrual cycles than in subsequent cycles, suggestive of an effect of participation in the study on hormone levels. Initial salivary OE2 levels were not good predictors of corresponding levels in either follicular or luteal phases of the menstrual cycles at the 6-month intervals. However, after the initial cycle, progesterone levels were highly predictable within individuals over a period of 6 months (r=0.78, P< 0.001). The study emphasizes the natural variation among and within women in the absence of any intervention, and indicates the need for properly controlled studies before attributing changes in hormonal levels to therapy. In addition, it emphasizes the importance of sampling at multiple time points when examining the relationship between hormones and risk.

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