Pharmacokinetics of atazanavir boosted with cobicistat in pregnant and postpartum women with HIV

About 17 million women around the world aged 15-49 years are infected with HIV and AIDS. HIV / AIDS is transmitted from mother to baby during pregnancy, intra-natal, postnatal and it is a cause of death. In 2015, HIV transmission occurred in more than 38,500 children born to HIV-positive women. Transmission of HIV / AIDS from mother to baby during labor can be prevented by ARV therapy. The psychological aspects of postpartum women with HIV / AIDS include fear, shame, and a higher risk of depression compared to normal postpartum. Social support is needed by individuals in the situation. The participants in this study were 6 people. The sampling technique used purposive sampling with the inclusion criteria for post-partum women with HIV / AIDS who routinely controlled treatment. The results of the study found the theme of psychosocial support from the closest person consisted of 3 categories, namely psychological support from the family, support from fellow friends with HIV / AIDS and support in undergoing treatment. Conclusions from the results of the study found new insights that post-partum women with HIV / AIDS had accumulated feeling from the process of HIV / AIDS. Support is needed from the people closest to the family and support from fellow friends with HIV / AIDS, to prevent continuing into the desperation stage that results in death.Keywords: HIV / AIDS, Physiological support, Perception, postpartum-women.

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Barriers to and Facilitators of HIV Serostatus Disclosure to Sexual Partners among Postpartum Women Living with HIV in South Africa

10.21203/rs.3.rs-24611/v3 ◽

2020 ◽

Author(s):

Oladele Vincent Adeniyi ◽

Charlotte Nwogwugwu ◽

Anthony Idowu Ajayi ◽

John Lambert

Keyword(s):

Sexual Partners ◽

Postpartum Women ◽

Study Cohort ◽

Hiv Status ◽

Sampling Weights ◽

Serostatus Disclosure ◽

Hiv Serostatus ◽

Women With Hiv ◽

Hiv Status Disclosure ◽

Status Disclosure

Abstract Background: Disclosure of HIV serostatus to sexual partner facilitates partner's support and testing, and correlates with better treatment outcomes. Studies examining changes in the rate of serostatus from delivery and postpartum periods are scarce. Our study fills this gap by using a follow-up survey of postpartum women with HIV to examine if disclosure prevalence has improved compared to the proportion recorded at childbirth. We further assessed the reasons for non-disclosure and correlates of serostatus disclosure to sexual partners. Methods: We conducted telephonic interviews with a final sample of 485 postpartum women with HIV drawn from the East London Prospective Cohort study database between January and May 2018. Disclosure of HIV status to partner was based on self-reporting. We fitted adjusted and unadjusted logistic regression models and also conducted descriptive statistical analyses. Sampling weights were used to correct for sampling errors. Results: Overall, 81.8% of women in the study cohort had disclosed their status to their partners, representing a 7.4 percentage point increase since child delivery. After adjusting for important covariates, women were more likely to disclose their status if they were married [adjusted odds ratio (AOR): 3.10; 95% confidence interval (CI):1.39-6.91] but were less likely to disclose if they use alcohol [AOR: 0.61; 95% CI:0.37-0.99] or reported sub-optimal adherence [AOR: 0.59; 95% CI:0.36-0.96]. Fear of rejection, stigma or being judged, new or casual relationships, and having a violent partner were the main reasons for not disclosing HIV status to sexual partners. Conclusion: We found a relatively higher rate of HIV status disclosure in the cohort compared to the rate recorded at childbirth, suggesting the likelihood of positive effect of post-delivery counselling. Also, complicated relationship dynamics and fear of social exclusion still constitute barriers to HIV status disclosure to sexual partners despite patients' counselling.

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HIV positive status disclosure to a sexual partner: the influence of marital status and partner communication

10.21203/rs.3.rs-24611/v1 ◽

2020 ◽

Author(s):

OLADELE VINCENT ADENIYI ◽

Charlotte Nwogwugwu ◽

Anthony Idowu Ajayi ◽

John Lambert

Keyword(s):

Sexual Partner ◽

Sexual Partners ◽

High Rate ◽

Postpartum Women ◽

Hiv Status ◽

Cross Sectional Survey ◽

Open Communication ◽

Cross Sectional ◽

Women With Hiv ◽

Status Disclosure

Abstract Background Disclosure of HIV serostatus to sexual partner does not only facilitate partner's support and testing, but it also correlates with better treatment outcomes. We drew from a cross-sectional survey data conducted among postpartum women with HIV to examine the rate of serostatus disclosure to sexual partners, the influence of relationship status, and knowing one's partner's status on disclosure and reasons for non-disclosure.Methods We conducted telephonic interviews with a final sample of 485 postpartum women with HIV drawn from the East London Prospective Cohort study database between January and May 2018. Disclosure of HIV status to partner was based on self-reporting. We fitted adjusted and unadjusted logistic regression models and also conducted descriptive statistical analyses.Results Overall, 82.5% of the respondents had disclosed their status to their partners. After adjusting for important covariates (age, education level, employment status, number of years since HIV diagnosis, alcohol use and smoking behaviour), being married [adjusted odd ratio (AOR): 2.66; 95% confidence interval (CI):1.17–6.05] and knowing one's partner's status [AOR: 46.91; 95% CI:19.50-112.81] were significantly associated with a higher odds of having disclosed HIV status to sexual partners. Fear of rejection, stigma or being judged, new or casual relationships, and having a violent partner were the main reasons for not disclosing HIV status to sexual partners.Conclusion We found a relatively high rate of HIV status disclosure in the cohort. Being married and having open communication with a partner about HIV status are important factors facilitating disclosure to sexual partners.

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Safer Conception and Family Planning Knowledge, Attitudes, and Practices Among Postpartum Women with HIV in Rural South Africa

Open Access Journal of Contraception ◽

10.2147/oajc.s288569 ◽

2021 ◽

Vol Volume 12 ◽

pp. 17-25

Author(s):

Lissa Mandell ◽

Violeta J Rodriguez ◽

Deborah L Jones

Keyword(s):

South Africa ◽

Family Planning ◽

Postpartum Women ◽

Safer Conception ◽

Rural South ◽

Attitudes And Practices ◽

Women With Hiv ◽

Knowledge Attitudes And Practices ◽

Rural South Africa ◽

Planning Knowledge

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HIV positive status disclosure to a sexual partner: the influence of marital status and partner communication

10.21203/rs.3.rs-24611/v2 ◽

2020 ◽

Author(s):

OLADELE VINCENT ADENIYI ◽

Charlotte Nwogwugwu ◽

Anthony Idowu Ajayi ◽

John Lambert

Keyword(s):

Sexual Partner ◽

Sexual Partners ◽

High Rate ◽

Postpartum Women ◽

Hiv Status ◽

Cross Sectional Survey ◽

Open Communication ◽

Cross Sectional ◽

Women With Hiv ◽

Status Disclosure

Abstract Background: Disclosure of HIV serostatus to sexual partner does not only facilitate partner's support and testing, but it also correlates with better treatment outcomes. We drew from a cross-sectional survey conducted among postpartum women with HIV to examine the rate of serostatus disclosure to sexual partners, the influence of relationship status, and knowing one's partner's status on disclosure and reasons for non-disclosure. Methods: We conducted telephonic interviews with a final sample of 485 postpartum women with HIV drawn from the East London Prospective Cohort study database between January and May 2018. Disclosure of HIV status to partner was based on self-reporting. We fitted adjusted and unadjusted logistic regression models and also conducted descriptive statistical analyses. Results: Overall, 82.5% of the respondents had disclosed their status to their partners. After adjusting for important covariates (age, education level, employment status, number of years since HIV diagnosis, alcohol use and smoking behaviour), being married [adjusted odds ratio (AOR): 2.66; 95% confidence interval (CI):1.17-6.05] and knowing one's partner's status [AOR: 46.91; 95% CI:19.50-112.81] were significantly associated with a higher odds of having disclosed HIV status to sexual partners. Fear of rejection, stigma or being judged, new or casual relationships, and having a violent partner were the main reasons for not disclosing HIV status to sexual partners. Conclusion: We found a relatively high rate of HIV status disclosure in the cohort. Being married and having open communication with a partner about HIV status are important factors facilitating disclosure to sexual partners.

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Exploring Physical Problems among Postpartum Women with Hiv/AIDS in West Java, Indonesia: A Qualitative Study

KnE Life Sciences ◽

10.18502/kls.v6i1.8754 ◽

2021 ◽

pp. 778-785

Author(s):

Nunung Nurhayati ◽

Agus Hendra

Keyword(s):

Qualitative Study ◽

Low Income ◽

Physical Symptoms ◽

Postpartum Women ◽

West Java ◽

Physical Problems ◽

Keywords Hiv ◽

Women With Hiv ◽

Hiv Drugs ◽

Hiv Aids

Indonesia is experiencing the fastest HIV/AIDS cases development in Asia, especially with regards to mother to child transmission levels. Postpartum women with HIV may suffer from a lot of physical problems due to the immune system disruption. Many of them have high risk for opportunistic infection such as tuberculosis, chronic diarrhea, and meningitis. Few studies have been conducted into these physical problems, especially in a low income country whereas the access to HIV drugs is still limited. This study aims to explore the physical problems among postpartum women with HIV/AIDS in West Java, Indonesia. This study used a qualitative design with a phenomenology approach. The semi-structured interview was used to collect information from women of between 24 and 38 years old, with a child with a maximum age of 12 months, and various other inclusion criteria. Purposive sampling was applied to select the participants. Colaizzi’s method was used to analyze the data. Six participants agreed to join in this study. We found three themes concerning the major physical problems experienced by postpartum women with HIV/AIDS: 1) physical response toward disease prognosis; 2) body weight changes, and 3) the side effects of HIV drugs. The most common physical symptoms were exhaustion, fever, headache, low back and joint pain, nausea, and weight change. Physical symptoms management design and implemented in health care services should provided for HIV/AIDS patients. Keywords: HIV/AIDS, Physical, Problems, Postpartum women, qualitative study

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