scholarly journals High Resolution Ultra High Field Magnetic Resonance Imaging of Glioma Microvascularity and Hypoxia Using Ultra-Small Particles of Iron Oxide

2009 ◽  
Vol 44 (7) ◽  
pp. 375-383 ◽  
Author(s):  
Gregory A. Christoforidis ◽  
Ming Yang ◽  
Marinos S. Kontzialis ◽  
Douglas G. Larson ◽  
Amir Abduljalil ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
High Resolution ◽  
High Field ◽  
Resonance Imaging ◽  
Small Particles ◽  
Ultra High Field

scholarly journals Ultra-high field (7T) functional magnetic resonance imaging in amyotrophic lateral sclerosis

2020 ◽  
Author(s):  
Robert L. Barry ◽  
Suma Babu ◽  
Sheeba Arnold Anteraper ◽  
Christina Triantafyllou ◽  
Boris Keil ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Amyotrophic Lateral Sclerosis ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Functional Connectivity ◽  
High Field ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Ultra High Field ◽  
Lateral Sclerosis

AbstractAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the central nervous system that results in a progressive loss of motor function and ultimately death. It is crit-ical, yet also challenging, to develop non-invasive biomarkers to identify, localize, measure and/or track biological mechanisms implicated in ALS. Such biomarkers may also provide clues to identify potential molecular targets for future therapeutic trials. Herein we report on twelve participants with ALS and nine age-matched healthy controls who underwent high-resolution resting state functional magnetic resonance imaging at an ultra-high field of 7 Tesla. Group-level whole-brain analyses revealed a disruption in long-range functional connectivity between the superior sensorimotor cortex (in the precentral gyrus) and bi-lateral cerebellar lobule VI. Post hoc analyses using atlas-derived left and right cerebellar lobule VI revealed decreased functional connectivity in ALS participants that predomi-nantly map to bilateral postcentral and precentral gyri. Cerebellar lobule VI is a transition zone between anterior motor networks and posterior non-motor networks in the cerebellum, and has been associated with a wide range of key functions including complex motor and cognitive processing tasks. Our observation of the involvement of cerebellar lobule VI adds to the growing number of studies implicating the cerebellum in ALS. Future avenues of scientific investigation should consider how high-resolution imaging at 7T may be leveraged to visualize differences in functional connectivity disturbances in various genotypes and phenotypes of ALS along the ALS-frontotemporal dementia spectrum.

scholarly journals Quantitative sodium imaging using ultra‐high field magnetic resonance imaging in patients with Alzheimer's disease

2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Alexa Haeger ◽  
Arthur Coste ◽  
Cécile Lerman‐Rabrait ◽  
Julien Lagarde ◽  
Jörg B. Schulz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Magnetic Resonance ◽  
High Field ◽  
Resonance Imaging ◽  
Ultra High Field ◽  
Sodium Imaging

The connective tissue and ligaments of the distal interphalangeal joint: a review and investigation using ultra-high field 16.4 Tesla magnetic resonance imaging

2013 ◽  
Vol 39 (4) ◽  
pp. 398-404 ◽  
Author(s):  
D. Slattery ◽  
C. Aland ◽  
G. Durbridge ◽  
G. Cowin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Connective Tissue ◽  
High Field ◽  
Three Dimensional ◽  
Interphalangeal Joint ◽  
Resonance Imaging ◽  
Distal Interphalangeal Joint ◽  
Ultra High Field ◽  
Distal Interphalangeal

This study reviews the literature on the anatomy of the connective tissues surrounding the distal interphalangeal joint and further characterizes the three-dimensional relationships of these structures with ultra-high field magnetic resonance imaging. Ten cadaver fingers, fixed in a solution of 5% agar and 4% formalin, were imaged utilising an ultrashield 16.4 Tesla ultra-high field magnetic resonance imaging, yielding a total of 4000 images. Images were analysed using Osirix™ (version 5.5.1 32 bit edition) for three-dimensional reconstruction. We found numerous conflicting descriptions of the connective tissue structures around the distal interphalangeal joint. Based upon our literature review and imaging studies we have defined precisely Cleland’s ligaments, the oblique proximal septum, Grayson’s ligaments, the dorsal plate, and the interosseous ligaments of the distal interphalangeal joint.

Advanced Musculoskeletal Magnetic Resonance Imaging at Ultra-high Field (7 T)

2011 ◽  
pp. 189-213 ◽  
Author(s):  
Siegfried Trattnig ◽  
Klaus Friedrich ◽  
Wolfgang Bogner ◽  
Klaus Scheffler ◽  
Oliver Bieri ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Field ◽  
Resonance Imaging ◽  
Ultra High Field

AB1098 STRUCTURAL ELEMENTS OF THE KNEE ENTHESES ASSESSED IN HEALTHY SUBJECTS WITH ULTRA HIGH FIELD MRI (150 MICRONS).

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1838-1838
Author(s):  
D. Roche ◽  
C. Michel ◽  
P. Daudé ◽  
A. Le Troter ◽  
C. Chagnaud ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Healthy Subjects ◽  
High Field ◽  
T2 Mapping ◽  
Pulse Sequences ◽  
Structural Elements ◽  
Resonance Imaging ◽  
Ultra High Field ◽  
Mineralized Zone

Background:Fibrocartilaginous enthesis is composed of different histological zones which are commonly referred to the tendon distal extremity (a lamellar tissue with a low cell density, collagen and connective tissue), the fibrocartilaginous zone (with chondrocytes), a progressively mineralized zone and the bone. The MRI visualization of the water content of entheses is challenging given the very short relation time so that entheses has been very poorly assessed using MRI (1).Objectives:The main objective of the study was to assess the structural elements of the knee enthesis based on the quantitative T2* measurements using Ultra High Field (UHF) MRI.Methods:Twelve healthy subjects without any osteoarticular pathology were included in the study after they provided their informed consent. 3D gradient echo sequence with a 4.3 ms echo time and T2* mapping were performed. The lateral internal, external and crossed ligaments, patellar and quadricipital tendons were assessed. T2* measurements were performed specifically on the quadricipital tendon.Results:The quadricipital tendon and the bone trabeculation could be visualized on the UHF MR image. The T2* mapping analysis illustrated a large value (16.4 ± 4 ms) for the subchondral bone and much lower values for the trabecular bone (11 ± 4.5 ms) and the different zones of the keen entheses (7.7 ± 1.9 ms).Conclusion:Based on T2* measurements performed using UHF MRI, the different structural elements of the knee entheses were distinguished. This quantitative stratification could be used to assess changes in pathological conditions such as SpA and trauma.References:[1]Benjamin M, Bydder GM. Magnetic resonance imaging of entheses using ultrashort TE (UTE) pulse sequences. Journal of magnetic resonance imaging: JMRI. 2007;25(2):381-9.Disclosure of Interests:None declared

scholarly journals P.063 Stereotactic targeting of hippocampal substructures using ultra-high field magnetic resonance imaging: Feasibility study in patients with epilepsy

2018 ◽  
Vol 45 (s2) ◽  
pp. S32-S33
Author(s):  
JC Lau ◽  
J DeKraker ◽  
KW MacDougall ◽  
H Joswig ◽  
AG Parrent ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Dentate Gyrus ◽  
High Field ◽  
Longitudinal Axis ◽  
The Body ◽  
7 Tesla ◽  
Resonance Imaging ◽  
Ultra High Field

Background: The hippocampus can be divided longitudinally into the head, body, and tail; and unfolded medial-to-laterally into the subiculum, cornu ammonis (CA) sectors, and the dentate gyrus. Ultra-high field (≥ 7 Tesla; 7T) magnetic resonance imaging (MRI) enables submillimetric visualization of these hippocampal substructures which could be valuable for surgical targeting. Here, we assess the feasibility of using 7T MRI in conjunction with a novel computational unfolding method for image-based stereotactic targeting of hippocampal substructures. Methods: 53 patients with drug-resistant epilepsy were identified undergoing first-time implantation of the hippocampus. An image processing pipeline was created for computationally transforming post-operative electrode contact locations into our hippocampal coordinate system. Results: Of 178 implanted hippocampal electrodes (88 left; 49.4%), 25 (14.0%) were predominantly in the subiculum, 85 (47.8%) were in CA1, 23 (12.9%) were in CA2, 18 (10.1%) were in CA3/CA4, and 27 (15.2%) were in dentate gyrus. Along the longitudinal axis, hippocampal electrodes were most commonly implanted in the body (92; 51.7%) followed by the head (86; 48.3%). Conclusions: 7T MRI enables high-resolution anatomical imaging on the submillimeter scale in in vivo subjects. Here, we demonstrate the utility of 7T imaging for identifying the relative location of SEEG electrode implantations within hippocampal substructures for the invasive investigation of epilepsy.

Sign in / Sign up

Export Citation Format

Share Document