Quantitative Assessment of Thyroid Gland Vascularization With Vascularization Index Using Color Superb Microvascular Imaging in Pediatric Patients With Hashimoto Thyroiditis

2019 ◽  
Vol 35 (3) ◽  
pp. 281-289 ◽  
Author(s):  
Mehmet Sedat Durmaz ◽  
Nesibe Akyürek ◽  
Turgay Kara ◽  
Fatih Ateş ◽  
Bora Özbakir ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Quantitative Assessment ◽  
Pediatric Patients ◽  
Hashimoto Thyroiditis ◽  
Superb Microvascular Imaging ◽  
Microvascular Imaging ◽  
Vascularization Index

scholarly journals Evaluation of parenchymal vascularity of the thyroid gland with vascularization index by color superb microvascular imaging in patients with Graves’ disease

2021 ◽  
Vol 21 (84) ◽  
pp. e41-e47
Author(s):  
Abidin Kılınçer ◽  
◽  
Mehmet Sedat Durmaz ◽  
Cem Onur Kıraç ◽  
Süleyman Baldane ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Region Of Interest ◽  
Clinical Findings ◽  
Graves Disease ◽  
Asymptomatic Group ◽  
Free Region ◽  
Superb Microvascular Imaging ◽  
Index Value ◽  
Microvascular Imaging ◽  
Vascularization Index

Aim of the study: To determine the parenchymal vascularity of the thyroid gland with color superb microvascular imaging in patients with Graves’ disease, and compare the vascularization index values with healthy subjects. Materials and methods: The thyroid glands of 37 patients whose laboratory and clinical findings were consistent with Graves’ disease, and 40 asymptomatic subjects with normal laboratory values, were examined using color superb microvascular imaging. Measurements of the vascularization index were performed with a free region of interest which was drawn along the outer margin of the gland on the color superb microvascular imaging mode. The vascularization index values obtained in the Graves’ disease and control groups were compared. A correlation analysis was performed between the vascularization index values and laboratory and grayscale US parameters. Results: The median vascularization index value of the thyroid parenchyma in patients with Graves’ disease was significantly higher than in the asymptomatic group [median (min–max); 12 (2.3–32.1) vs 5.04 (1.1–10.8), p <0.001]. When the cutoff value of the vascularization index is determined as 6.3, Graves’ disease can be diagnosed with 83.8% sensitivity and 70% specificity. Conclusions: The vascularization index obtained with color superb microvascular imaging can be a quantitative indicator of parenchymal vascularity in the diagnosis of Graves’ disease, and serve as a supportive tool.

scholarly journals Using 2-dimensional color superb microvascular imaging vascularization index technique in the assessment of thyroid surgical bed

2021 ◽  
Author(s):  
Mehmet Sedat Durmaz ◽  
Gonca Kara Gedik ◽  
Abdussamet Batur ◽  
Farise Yılmaz
Keyword(s):  
Control Group ◽  
Normal Thyroid ◽  
Remnant Thyroid ◽  
Free Region ◽  
Group A ◽  
Superb Microvascular Imaging ◽  
Group B ◽  
Microvascular Imaging ◽  
Thyroid Parenchyma ◽  
Vascularization Index

Aim: The purpose of this study was to investigate the effectiveness of the vascularization index (VI) obtained using color superb microvascular imaging (cSMI) technique in the assessment of thyroid surgical bed for remnant thyroid tissue (RTT). Material and methods: We evaluated the thyroid surgical bed of 65 patients who had underwent total thyroidectomy (TT) due to papillary carcinoma (PC) using thyroid scintigraphy and cSMI. Color SMI was also performed for the examination of the thyroid parenchyma of 39 healthy asymptomatic participants. VI measurements were performed by manually drawing the contours of the RTT in those with remnant thyroid, the thyroid surgical bed in the patients’ group without remnant thyroid, and normal thyroid parenchyma in the control group, using the free region of interest (ROI) with 2-dimensional color SMI VI (2DcSMIVI) mode. The volume of ROI was measured and echogenicity was evaluated. The quantitative 2DcSMIVI values of the surgical bed with RTT (Group A), the surgical bed without RTT (Group B) and normal thyroid of healthy asymptomatic participants (Group C) were compared. Results: The mean 2DcSMIVI values of Group A was significantly higher than Group B and C (p=0.001). The presence of RTT can be diagnosed with 89.1% sensitivity and 87.5% specificity when 1.75 2DcSMIVI is designated as the cut-off value. Conclusion: The 2DcSMIVI is an effective imaging technique that can be used for the diagnosis of RTT.

Superb Microvascular Imaging in the Evaluation of Pediatric Graves Disease and Hashimoto Thyroiditis

2019 ◽  
Vol 39 (5) ◽  
pp. 901-909 ◽  
Author(s):  
Zuhal Bayramoglu ◽  
Sedat Giray Kandemirli ◽  
Zeynep Nur Akyol Sarı ◽  
Aslı Derya Kardelen ◽  
Sukran Poyrazoglu ◽  
...  
Keyword(s):  
Hashimoto Thyroiditis ◽  
Graves Disease ◽  
Superb Microvascular Imaging ◽  
Microvascular Imaging

Quantitative assessment of thyroid gland elasticity with shear-wave elastography in pediatric patients with Hashimoto’s thyroiditis

2018 ◽  
Vol 45 (3) ◽  
pp. 417-423 ◽  
Author(s):  
Sedat Giray Kandemirli ◽  
Zuhal Bayramoglu ◽  
Emine Caliskan ◽  
Zeynep Nur Akyol Sari ◽  
Ibrahim Adaletli
Keyword(s):  
Thyroid Gland ◽  
Shear Wave ◽  
Hashimoto’S Thyroiditis ◽  
Quantitative Assessment ◽  
Pediatric Patients ◽  
Shear Wave Elastography ◽  
Hashimoto's Thyroiditis

scholarly journals Analysis of vascularization in thyroid gland nodes with superb microvascular imaging (SMI) and CD34 expression histology: a pilot study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Thomas Studeny ◽  
Wolfgang Kratzer ◽  
Julian Schmidberger ◽  
Tilmann Graeter ◽  
Thomas F. E. Barth ◽  
...  
Keyword(s):  
Image Analysis ◽  
Thyroid Gland ◽  
Follicular Carcinoma ◽  
Diagnostic Value ◽  
Malignant Tumours ◽  
Tissue Slices ◽  
Computational Evaluation ◽  
Superb Microvascular Imaging ◽  
Microvascular Imaging ◽  
Cd34 Expression

Abstract Background The Doppler sonography technique known as "superb microvascular imaging" (SMI) is advancing sonographic micro vascularization imaging in various disciplines. In this study, we aimed to determine whether SMI could reliably reproduce the blood flow in thyroid nodes and whether malignancy could be diagnosed, based on vascularization properties. Immunhistochemical staining by CD34 and SMI where used to determine the vascularization of nodes in terms of quantified vascularization parameters gained by computational evaluation. Methods We used image analysis programs to investigate whether the quantitative value for vascularization strength in the thyroid node, measured with SMI, was correlated with the actual degree of vascularization, determined microscopically. We included 16 patients that underwent thyroid resections. We prepared thyroid gland tissue slices for immunohistochemistry and labelled endothelial cells with CD34 to visualize blood vessels microscopically. We used image analysis programs, ImageJ, to quantify SMI Doppler sonographic measurements and CellProfiler to quantify CD34 expression in histological sections. We evaluated the numeric values for diagnostic value in node differentiation. Furthermore, we compared these values to check for correlations. Results Among the 16 nodes studied, three harboured malignant tumours (18.75%): two papillary and one follicular carcinoma. Among the 13 benign lesions (81.25%), four harboured follicular adenomas. Malignant and benign nodes were not significantly different in sonographic (0.88 ± 0.89 vs. 1.13 ± 0.19; p = 0.2790) or immunohistochemical measurements of vascularization strength (0.05 ± 0.05 vs. 0.08 ± 0.06; p = 0.2260). Conclusion We found a positive, significant correlation (r = 0.55588; p = 0.0254) between SMI (quantitative values for vascularization strength) and immunohistochemistry (CD34 staining) evaluations of thyroid nodes.

scholarly journals Efficacy of dynamic quadripolar radiofrequency assessed by advanced ultrasound technologies

2021 ◽  
Vol 4 (4) ◽  
pp. 311-316
Author(s):  
Yu.E. Dobrokhotova ◽  
◽  
V.I. Komagorov ◽  
I.Yu. Il’ina ◽  
I.I. Grishin ◽  
...  
Keyword(s):  
Surgical Intervention ◽  
Pelvic Organ ◽  
Rehabilitation Program ◽  
Tissue Elasticity ◽  
Radiofrequency Therapy ◽  
Superb Microvascular Imaging ◽  
Group 2 ◽  
Microvascular Imaging ◽  
Vascularization Index ◽  
Group 1

Aim: to develop a postoperative rehabilitation program for women with pelvic organ prolapse (POP). Patients and Methods: sixty postmenopausal women aged 55–75 with POP were randomized into two equal groups. All women underwent surgical intervention, which included anterior and posterior colporrhaphy and colpoperineo-levator-plasty. Group 1 women underwent five courses of radiofrequency therapy with a 14-day interval 30 days after surgery. Radiofrequency exposure was addressed by dynamic quadripolar radiofrequency (DQRF). Group 2 women were followed up without any additional rehabilitation measures. Ultrasound (US) examination using compression elastography was performed in all women To assess tissue elasticity. Neovascularization of vaginal walls was evaluated by superb microvascular imaging (SMI). The vascular intensity of the selected area of the vaginal wall was measured by automatic calculation of the vascularization index. US was performed twice, e.g., before and after surgery and rehabilitation (in group 1) or three months after surgery (in group 2). Results: in women who underwent DQRF therapy, an increase in the elasticity of vaginal walls was reported that indirectly demonstrates the increase in type 1 collagen and improvement of tissue vascularization. After surgery and radiofrequency therapy, the vascularization index increased by 1.6 times in group 1 and 1.2 times in group 2 compared to baseline. No postoperative complications were reported. Conclusion: this rehabilitation program is recommended for women who underwent surgical intervention for POP, given the efficacy and safety of radiofrequency therapy in the postoperative period. KEYWORDS: pelvic organ prolapse, rehabilitation period, dynamic quadripolar radiofrequency, dynamic quadripolar radiofrequency therapy, tissue elasticity, neovascularization, elastography, superb microvascular imaging. FOR CITATION: Dobrokhotova Yu.E., Komagorov V.I., Il’ina I.Yu. et al. Efficacy of dynamic quadripolar radiofrequency assessed by advanced ultrasound technologies. Russian Journal of Woman and Child Health. 2021;4(4):311–316 (in Russ.). DOI: 10.32364/2618- 8430-2021-4-4-311-316.

scholarly journals Assessment of thyroid gland vascularity with superb microvascular imaging in healthy children and its relationship with potential factors

2020 ◽  
Vol 33 (9) ◽  
pp. 1139-1145
Author(s):  
Mehmet Ozturk ◽  
Mehmet Sedat Durmaz ◽  
Fatih Ateş ◽  
Turgay Kara ◽  
Funda Gökgöz Durmaz ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Age Groups ◽  
Thyroid Stimulating Hormone ◽  
Left Lobe ◽  
Healthy Children ◽  
Significant Difference ◽  
Superb Microvascular Imaging ◽  
Potential Factors ◽  
The Right ◽  
Microvascular Imaging

AbstractObjectivesTo define thyroid gland vascularity index (VI) values in healthy children with the superb microvascular imaging (SMI) method and to assess whether or not there is a correlation with potential factors that may affect these values.MethodsThis prospective study included a total of 138 children, their ages varying from 3–17 years. Cases were divided into three subgroups according to age: 3–6, 7–12 and 13–17 years. Gender, age, height, weight, body mass index (BMI), thyroid-stimulating hormone (TSH) and free thyroxine (fT4) values were recorded. Volume and SMI measurements were performed with a 14 L5 mHz linear transducer. VI measurements were performed in the transverse and longitudinal planes and correlation with basic descriptive data was researched.ResultsMean age was 11.14 ± 3.34 years and BMI was 19.95 ± 4.92. VI values were 4.59 ± 2.34 in the right lobe and 4.23 ± 2.73 for the left lobe, with no significant difference identified. There were no significant differences in mean VI for all parenchyma regarding gender and age groups. While there was no correlation identified with mean VI for all parenchyma with TSH and fT4, there was, however, a negative correlation with BMI.ConclusionsReference VI values for normal thyroid glands in healthy children and adolescents were defined with the SMI method. There was no correlation between the VI values and age, gender, volume, TSH and fT4 values, while there was a negative significant correlation with BMI.

Sign in / Sign up

Export Citation Format

Share Document