A Giant Tumefactive Virchow-Robin Space

2017 ◽  
Vol 37 (1) ◽  
pp. 75-76 ◽  
Author(s):  
Alysse Rivet ◽  
Anne-Sophie Gauthier ◽  
Marion Chatain ◽  
Romain Billon-Grand ◽  
Laurent Thines ◽  
...  
Keyword(s):  
Author(s):  
Youming Long ◽  
Zhengqi Lu ◽  
Xueqiang Hu

Objective:To compare the clinical features of our sero-negative and sero-positive neuromyelitis optica (NMO) patients.Methods:Thirty-nine patients with NMO were recruited and analyzed retrospectively. Serum aquaporin 4 (AQP4) antibody status was determined by a cell-based assay. For the sero-negative patients, cerebrospinal fluid (CSF) and serum samples were re-tested using the cell-based assay and an indirect immunofluorescence assay.Results:By the cell-based assay, 30 patients (76.92%, 30/39), were positive for AQP4 antibodies in serum and 37 patients (94.9%, 37/39), had a CSF-positive antibody status. Seven NMO patients (17.9%, 7/39) were sero-negative by the cell-based assay but demonstrated positive CSF results. By indirect immunofluorescence, the remaining two patients, who had no AQP4 antibodies in serum or CSF by the cell-based assay, were positive for IgG antibodies in serum, which selectively targeted the central nervous system microvessels, pia, subpia, Virchow-Robin space, kidney, and stomach. There were no significant differences between the sero-positive and sero-negative NMO groups among their demographic and clinical data.Conclusions:Repeating the test using a different assay or CSF is helpful to clarify whether sero-negative NMO patients do in fact carry AQP4 antibodies.


2017 ◽  
Vol 109 ◽  
pp. 114-118 ◽  
Author(s):  
Patrick Chan ◽  
Denis J. Meerdink ◽  
James A. Uchizono

2011 ◽  
Vol 35 (2) ◽  
pp. 298-302 ◽  
Author(s):  
Ah Young Park ◽  
Tae-Sub Chung ◽  
Sang Hyun Suh ◽  
Hyun Seok Choi ◽  
Yun Hee Lee

Radiology ◽  
1986 ◽  
Vol 158 (3) ◽  
pp. 715-720 ◽  
Author(s):  
M Mirfakhraee ◽  
M J Crofford ◽  
F C Guinto ◽  
H J Nauta ◽  
V W Weedn
Keyword(s):  

2007 ◽  
Vol 97 (1-3) ◽  
pp. 265-270 ◽  
Author(s):  
Tufail F. Patankar ◽  
Robert Baldwin ◽  
Dipayan Mitra ◽  
Suzanne Jeffries ◽  
Caroline Sutcliffe ◽  
...  

Author(s):  
Dokyung Lee ◽  
Il Ki Hong ◽  
Tae-Beom Ahn

AbstractObjective: The radiological and clinical significance of a dilated Virchow-Robin space (dVRS) in the striatum (STR) remains unclear. We investigated the role of dVRS in STR on parkinsonism and dopamine transporter positron emission tomography (DaT-PET) findings. Methods: Patients with parkinsonism who underwent both brain magnetic resonance imaging and DaT-PET were included. Clinical status was evaluated by Hoehn and Yahr (HY) stage, Korean-Mini Mental Status Examination (K-MMSE), Montreal Cognitive Assessment Korea (MoCA-K), and Frontal Assessment Battery (FAB). dVRS was assessed by semi-quantitative and quantitative scales in each of the three segments of STR (caudate nuclei, anterior and posterior putamen) and was expressed as a dVRS score. DaT-PET was qualitatively assessed as either normal or abnormal in each segment. The relationship between dVRS and DaT-PET abnormality (ab-DaT-PET) was designated in each segment as either concordant or discordant. A concordant segment was defined by the presence of dVRS with ab-DaT-PET [Concordance rate (CR)=number of concordant segments/number of concordant and discordant segments]. Results: Eleven patients were included. There was no significant correlation between the presence of dVRS and ab-DaT-PET. The mean CR was 0.39. CR was not significantly correlated with any clinical or neuroimaging scales. The dVRS score was significantly correlated with K-MMSE, MoCA-K, and FAB (r=−0.675, −0.847, and −0.868, respectively) but not with HY stage. Conclusion: dVRS in STR played no significant role on dopaminergic innervation revealed by DaT-PET and made little contribution to clinical parkinsonism; however, it was correlated with cognitive impairment.


2011 ◽  
Vol 21 (3) ◽  
pp. 214-218 ◽  
Author(s):  
Sachin Sampat Baldawa ◽  
Hariharan Venkat Easwer ◽  
Suresh Nair ◽  
Girish Menon

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