scholarly journals Fetal Electrocardiogram Extraction from the Mother’s Abdominal Signal Using the Ensemble Kalman Filter

2021 ◽  
Author(s):  
Sadaf Sarafan ◽  
Tai Le ◽  
Michael P.H. Lau ◽  
Afshan Hameed ◽  
Tadesse Ghirmai ◽  
...  
Keyword(s):  
Kalman Filter ◽  
Ensemble Kalman Filter ◽  
Congenital Heart ◽  
Single Channel ◽  
Heart Defects ◽  
Qrs Complex ◽  
Fetal Electrocardiogram ◽  
High Noise ◽  
Non Invasive ◽  
Novel Algorithm

AbstractFetal electrocardiogram (fECG) assessment is essential throughout pregnancy to monitor the wellbeing and development of the fetus, and to possibly diagnose potential congenital heart defects. Due to the high noise incorporated in the abdominal ECG (aECG) signals, the extraction of fECG has been challenging. And it is even a lot more difficult for fECG extraction if only one channel of aECG is provided, i.e. in a compact patch device. In this paper, we propose a novel algorithm based on the Ensemble Kalman Filter (EnKF) for non-invasive fECG extraction from a single-channel aECG signal. To assess the performance of the proposed algorithm, we used our own clinical data, obtained from a pilot study with 10 subjects each of 20 min recording, and data from the PhysioNet 2013 Challenge bank with labeled QRS complex annotations. The proposed methodology shows the average positive predictive value (PPV) of 97.59%, sensitivity (SE) of 96.91%, and F1-score of 97.25% from the PhysioNet 2013 Challenge bank. Our results also indicate that the proposed algorithm is reliable and effective, and it outperforms the recently proposed Extended Kalman Filter (EKF) based algorithm.

scholarly journals Determination of urinary d-/l-arabinitol ratios as a biomarker for invasive candidiasis in children with cardiac diseases

2010 ◽  
Vol 59 (12) ◽  
pp. 1490-1496 ◽  
Author(s):  
Teresa J. Stradomska ◽  
Dorota Sobielarska ◽  
Zbigniew Mielniczuk ◽  
Dorota Jagiełłowicz ◽  
Małgorzata Syczewska ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Congenital Heart Defects ◽  
Invasive Candidiasis ◽  
Predictive Value ◽  
Congenital Heart ◽  
Heart Defects ◽  
Cardiac Diseases ◽  
Non Invasive ◽  
Antifungal Chemotherapy

A non-invasive, non-culture-based method of determining urinary d-/l-arabinitol (d-/l-ARA) ratios was investigated as a tool for the diagnosis of invasive candidiasis in nosocomial paediatric infection cases. The study encompassed 138 children aged 4 days to 16 years (mean±sd=1.6±4.2 years) with congenital heart defects (91.4 %) or with rhythm disorders or circulatory failure (8.6 %). ARA enantiomers were detected by GC using an electron capture detector. Positive d-/l-ARA ratios were found for 11/11 patients with proven candidiasis and 17/19 patients with clinically suspected invasive candidiasis. Thirty children were undergoing antifungal chemotherapy. d-/l-ARA ratios (mean±sd) were 2.601±0.544 in hospitalized cardiac patients without fungal infection and 5.120±1.253 in those receiving antifungal therapy (P<0.001). The sensitivity of the method was 100 %, the specificity 97.2 %, the positive predictive value was 78.6 % and the negative predictive value was 100 %.

Using chromosomal and single-gene non-invasive prenatal testing to identify the cause of congenital heart defects

2021 ◽  
Vol 132 ◽  
pp. S319-S320
Author(s):  
Mark Hajjar ◽  
Pooja Mohan ◽  
Jacob Wulff ◽  
Melissa Maisenbacher ◽  
J. Dianne Keen-Kim ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Single Gene ◽  
Prenatal Testing ◽  
Non Invasive

Recommendations from the Association for European Paediatric and Congenital Cardiology for training in diagnostic and interventional electrophysiology

2020 ◽  
pp. 1-9
Author(s):  
Thomas Kriebel ◽  
Eric Rosenthal ◽  
Roman Gebauer ◽  
Juha-Matti Happonen ◽  
Fabrizio Drago ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Defects ◽  
Electronic Devices ◽  
Paediatric Cardiology ◽  
Non Invasive ◽  
Cardiac Implantable Electronic Devices ◽  
Interventional Electrophysiology ◽  
European Paediatric ◽  
Inherited Arrhythmias

Abstract The field of electrophysiology (EP) in paediatric cardiology patients and adults with congenital heart disease is complex and rapidly growing. The current recommendations for diagnostic and invasive electrophysiology of the working group for Cardiac Dysrhythmias and Electrophysiology of the Association for European Paediatric and Congenital Cardiology acknowledges the diveristy of European countries and centers. These training recommendations can be fulfilled in a manageable period of time, without compromising the quality of training required to become an expert in the field of paediatric and congenital EP and are for trainees undergoing or having completed accredited paediatric cardiologist fellowship. Three levels of expertise, the training for General paediatric cardiology EP, for non-invasive EP and invasive EP have been defined. This Association for European EP curriculum describes the theoretical and practicsal knowledge in clinical EP; catheter ablation, cardiac implantable electronic devices, inherited arrhythmias and arrhythmias in adults with congenital heart defects for the 3 levels of expertise.

scholarly journals Sedation and anaesthesia for cardiac catheterisation

2020 ◽  
pp. S19-S21
Author(s):  
A Schure
Keyword(s):  
Treatment Option ◽  
Congenital Heart Defects ◽  
Diagnostic Tool ◽  
Cardiac Mri ◽  
Congenital Heart ◽  
Imaging Techniques ◽  
Heart Defects ◽  
Cardiac Catheterisation ◽  
Paediatric Cardiology ◽  
Non Invasive

Since the introduction of cardiac catheterisation for Paediatric Cardiology in 1947, the subspecialty has seen dramatic changes. The advancement of non-invasive imaging techniques such as echocardiography, CT and cardiac MRI has shifted the focus for paediatric cardiac catheterisations from a primarily diagnostic tool (to define anatomy, assess haemodynamics and calculate shunts) to an important treatment option for various congenital heart defects.

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