scholarly journals A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence.

1990 ◽  
Vol 4 (1) ◽  
pp. 29-42 ◽  
Author(s):  
C M Fan ◽  
T Maniatis
Keyword(s):  
Dna Binding ◽  
Dna Sequence ◽  
Zinc Finger ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Zinc Finger Motifs

scholarly journals A plant DNA-binding protein that recognizes 5-methylcytosine residues.

1989 ◽  
Vol 9 (3) ◽  
pp. 1351-1356 ◽  
Author(s):  
D L Zhang ◽  
K C Ehrlich ◽  
P C Supakar ◽  
M Ehrlich
Keyword(s):  
Dna Binding ◽  
Dna Sequence ◽  
Base Pair ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Sequence Specificity ◽  
Dna Sequence Specificity ◽  
Plant Dna ◽  
Related Family ◽  
Nuclear Extracts

A novel, 5-methylcytosine-specific, DNA-binding protein, DBP-m, has been identified in nuclear extracts of peas. DBP-m specifically recognizes 5-methylcytosine residues in DNA without appreciable DNA sequence specificity, unlike a mammalian DNA-binding protein (MDBP), which recognizes 5-methylcytosine residues but only in a related family of 14-base-pair sequences.

scholarly journals Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein.

1991 ◽  
Vol 11 (5) ◽  
pp. 2665-2674 ◽  
Author(s):  
A S Perkins ◽  
R Fishel ◽  
N A Jenkins ◽  
N G Copeland
Keyword(s):  
Dna Binding ◽  
Binding Site ◽  
Zinc Finger ◽  
Sequence Data ◽  
Binding Protein ◽  
Consensus Sequence ◽  
Dna Binding Protein ◽  
Polymerase Chain Reaction Method ◽  
Nucleotide Sequence Data ◽  
Carboxy Terminal

Evi-1 was originally identified as a common site of viral integration in murine myeloid tumors. Evi-1 encodes a 120-kDa polypeptide containing 10 zinc finger motifs located in two domains 380 amino acids apart and an acidic domain located carboxy terminal to the second set of zinc fingers. These features suggest that Evi-1 is a site-specific DNA-binding protein involved in the regulation of RNA transcription. We have purified Evi-1 protein from E. coli and have employed a gel shift-polymerase chain reaction method using random oligonucleotides to identify a high-affinity binding site for Evi-1. The consensus sequence for this binding site is TGACAAGATAA. Evi-1 protein specifically protects this motif from DNase I digestion. By searching the nucleotide sequence data bases, we have found this binding site both in sequences 5' to genes in putative or known regulatory regions and within intron sequences.

scholarly journals The ZNF35 human zinc finger gene encodes a sequence-specific DNA-binding protein

FEBS Letters ◽  
1993 ◽  
Vol 321 (2-3) ◽  
pp. 233-236 ◽  
Author(s):  
Gina Pengue ◽  
Paola Cannada-Bartoli ◽  
Luigi Lania
Keyword(s):  
Dna Binding ◽  
Zinc Finger ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Zinc Finger Gene

scholarly journals Solution Structure of an Archaeal DNA Binding Protein with an Eukaryotic Zinc Finger Fold

PLoS ONE ◽  
2013 ◽  
Vol 8 (1) ◽  
pp. e52908 ◽  
Author(s):  
Florence Guillière ◽  
Chloé Danioux ◽  
Carole Jaubert ◽  
Nicole Desnoues ◽  
Muriel Delepierre ◽  
...  
Keyword(s):  
Dna Binding ◽  
Zinc Finger ◽  
Solution Structure ◽  
Binding Protein ◽  
Dna Binding Protein
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