Quantum dot defines as a nanoparticle with particle size smaller than its exciton Bohr radius. Due to the remarkable quantum effects such as optical and electronic properties, they have attracted a great deal of attention by researchers and industries. Therefore, quantum dots have become a major topic in nano-technology. Here, we describe the most recent eco-friendly techniques that have been used to synthesize quantum dots, including biogenic methods, such as plant-mediated, microorganisms-mediated methods, wet chemical and solid-state methods.