Synthesis, crystal structure and Hirshfeld surface analysis of 2-(perfluorophenyl)acetamide in comparison with some related compounds
2022 ◽
Vol 78
(1)
◽
Keyword(s):
The molecular and crystal structures of the title compound, C8H4F5NO, were examined by single-crystal X-ray diffraction and Hirshfeld surface analysis. The title compound was synthesized by a new method at the interface of aqueous solutions of LiOH and pentafluorophenylacetonitrile. In the crystal, hydrogen bonds and π–halogen interactions connect the molecules into double layers. Analysis of the Hirshfeld surface showed that the most important contributions to the crystal packing are made by F...F (30.4%), C...F/F...C (22.9%), O...H/H...O (14.9%), H...F/F...H (14.0%) and H...H (10.2%) contacts. The Hirshfeld surfaces of analogues of the title compound were compared and the effect of perfluorination on the crystal packing was shown.
2020 ◽
Vol 76
(10)
◽
pp. 1557-1561
Keyword(s):
2017 ◽
Vol 73
(4)
◽
pp. 524-527
2019 ◽
Vol 75
(2)
◽
pp. 237-241
◽
Keyword(s):
2021 ◽
Vol 77
(4)
◽
pp. 356-359
Keyword(s):
2020 ◽
Vol 76
(4)
◽
pp. 594-598
Keyword(s):
2018 ◽
Vol 74
(3)
◽
pp. 385-389
◽
2020 ◽
Vol 76
(6)
◽
pp. 811-815
◽
2018 ◽
Vol 74
(12)
◽
pp. 1746-1750
◽
2021 ◽
Vol 77
(12)
◽
2021 ◽
Vol 77
(5)
◽
pp. 512-515