Automatic detection of optic disc using distance regularized level-set segmentation for glaucoma screening system

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Naganagouda Patil ◽  
Preethi N. Patil ◽  
P.V. Rao

PurposeThe abnormalities of glaucoma have high impact on deciding and representing the causes that effects severity of blindness in human beings. The simulation experimental results would help the ophthalmologist in diagnosing of glaucoma abnormality accurately. The significant effect of glaucoma has a huge impact on the quality of human life, and its growth rate in world population tremendously increases. Glaucoma is considered as second largest cause for the blindness in the world; hence identification of it marks the importance of its detection at the earliest.Design/methodology/approachThe prime objective of the work proposed is to build up a human intervention free image preparing framework for glaucoma screening. The disc calculation is assessed on retinal image dataset called retinal Image for glaucoma Analysis. The proposed method briefs a novel optic disc division calculation depending on applying a level-set strategy on a confined optic disc image. In the instance of low quality image, a twofold level set is designed, in which the principal level set is viewed as restriction for the optic disc. To keep the veins from meddling with the level-set procedure, an inpainting strategy has been applied. Also a significant commitment is to include the varieties in notion adopted by the ophthalmologists in distinguishing the disc localization and diagnosing the glaucoma. Most of the past investigations are prepared and tested depending on just a single feature, which can be thought to be one-sided for the ophthalmologist.FindingsIn continuation, the correctness has been determined depending on the quantity of image that matched with the investigation pattern adopted by the ophthalmologist. The 175 retinal images were utilized to test the results of proposed work with the manual markings of ophthalmologists. The error-free calculation in marking the optic disc region and centroid was 98.95% in comparison with the existing result of 87.34%.Originality/valueIn continuation, the correctness has been determined depending on the quantity of image that matched with the investigation pattern adopted by the ophthalmologist. The 175 retinal images were utilized to test the results of proposed work with the manual markings of ophthalmologists. The error-free calculation in marking the optic disc region and centroid was 98.95% in comparison with the existing result of 87.34%.

2020 ◽  
Author(s):  
S. Anand ◽  
R. Prabhadevi ◽  
D. Rini

ABSTRACTIn this paper an algorithm to detect the optic disc (OD) automatically is described. The proposed method is based on the circular brightness of the OD and its correlation coefficient. At first the peak intensity points are taken, a mask is generated for the given image which gives the circular bright regions of the image. To locate the OD accurately, a pattern is generated which is similar to the OD. By correlating the retinal image with the pattern generated, the maximum correlation of the pattern with the OD is obtained. On locating the coordinates of maximum correlation, the exact location of the OD is detected. The proposed algorithm has been tested with DRIVE database images and an average OD detection accuracy of 95% was obtained for healthy and pathological retinas respectively.


2020 ◽  
Vol 10 (14) ◽  
pp. 4916
Author(s):  
Syna Sreng ◽  
Noppadol Maneerat ◽  
Kazuhiko Hamamoto ◽  
Khin Yadanar Win

Glaucoma is a major global cause of blindness. As the symptoms of glaucoma appear, when the disease reaches an advanced stage, proper screening of glaucoma in the early stages is challenging. Therefore, regular glaucoma screening is essential and recommended. However, eye screening is currently subjective, time-consuming and labor-intensive and there are insufficient eye specialists available. We present an automatic two-stage glaucoma screening system to reduce the workload of ophthalmologists. The system first segmented the optic disc region using a DeepLabv3+ architecture but substituted the encoder module with multiple deep convolutional neural networks. For the classification stage, we used pretrained deep convolutional neural networks for three proposals (1) transfer learning and (2) learning the feature descriptors using support vector machine and (3) building ensemble of methods in (1) and (2). We evaluated our methods on five available datasets containing 2787 retinal images and found that the best option for optic disc segmentation is a combination of DeepLabv3+ and MobileNet. For glaucoma classification, an ensemble of methods performed better than the conventional methods for RIM-ONE, ORIGA, DRISHTI-GS1 and ACRIMA datasets with the accuracy of 97.37%, 90.00%, 86.84% and 99.53% and Area Under Curve (AUC) of 100%, 92.06%, 91.67% and 99.98%, respectively, and performed comparably with CUHKMED, the top team in REFUGE challenge, using REFUGE dataset with an accuracy of 95.59% and AUC of 95.10%.


2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Asloob Ahmad Mudassar ◽  
Saira Butt

A retinal image has blood vessels, optic disc, fovea, and so forth as the main components of an image. Segmentation of these components has been investigated extensively. Principal component analysis (PCA) is one of the techniques that have been applied to segment the optic disc, but only a limited work has been reported. To our knowledge, fovea segmentation problem has not been reported in the literature using PCA. In this paper, we are presenting the segmentation of optic disc and fovea using PCA. The PCA was trained on optic discs and foveae using ten retinal images and then applied on seventy retinal images with a success rate of 97% in case of optic discs and 94.3% in case of fovea. Conventional algorithms feed one patch at a time from a test retinal image, and the next patch separated by one pixel part is fed. This process is continued till the full image area is covered. This is time consuming. We are suggesting techniques to cut down the processing time with the help of binary vessel tree of a given test image. Results are presented to validate our idea.


PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2003 ◽  
Author(s):  
Muhammad Abdullah ◽  
Muhammad Moazam Fraz ◽  
Sarah A. Barman

Automated retinal image analysis has been emerging as an important diagnostic tool for early detection of eye-related diseases such as glaucoma and diabetic retinopathy. In this paper, we have presented a robust methodology for optic disc detection and boundary segmentation, which can be seen as the preliminary step in the development of a computer-assisted diagnostic system for glaucoma in retinal images. The proposed method is based on morphological operations, the Circular Hough transform and the Grow Cut algorithm. The morphological operators are used to enhance the optic disc and remove the retinal vasculature and other pathologies. The optic disc center is approximated using the Circular Hough transform, and the Grow Cut algorithm is employed to precisely segment the optic disc boundary. The method is quantitatively evaluated on five publicly available retinal image databases DRIVE, DIARETDB1, CHASE_DB1, DRIONS-DB, Messidor and one local Shifa Hospital Database. The method achieves an optic disc detection success rate of 100% for these databases with the exception of 99.09% and 99.25% for the DRIONS-DB, Messidor, and ONHSD databases, respectively. The optic disc boundary detection achieved an average spatial overlap of 78.6%, 85.12%, 83.23%, 85.1%, 87.93%, 80.1%, and 86.1%, respectively, for these databases. This unique method has shown significant improvement over existing methods in terms of detection and boundary extraction of the optic disc.


2015 ◽  
Vol 13 (2) ◽  
pp. 1-13 ◽  
Author(s):  
A. Elbalaoui ◽  
Mohamed Fakir ◽  
M. Boutaounte ◽  
A. Merbouha

Digital images of the retina is widely used for screening of patients suffering from sight threatening diseases such as Diabetic retinopathy and Glaucoma. The localization of the Optic Disc (OD) center is the first and necessary step identification and segmentation of anatomical structures and in pathological retinal images. From the center of the optic disc spreads the major blood vessels of the retina. Therefore, by considering the high number of vessels and the high number of the angles resulted from the vessels crossing, the authors propose a new method based on the number of angles in the vicinity of optic disc for localization of the center of optic disc. The first step is pre-processing of retinal image for separate the fundus from its background and increase the contrast between contours. In the second step, the authors use the Curvature Scale Space (CSS) for angle detection. In the next step, they move a window about the size of optic disc to count the number of corners. In the final step, they use the center of windows which has the most number of corners for localizing the optic disc center. The proposed method is evaluated on DRIVE, CHASE_DB1 and STARE databases and the success rate is 100, 100 and 96.3%, respectively.


2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Kemal Akyol ◽  
Baha Şen ◽  
Şafak Bayır

With the advances in the computer field, methods and techniques in automatic image processing and analysis provide the opportunity to detect automatically the change and degeneration in retinal images. Localization of the optic disc is extremely important for determining the hard exudate lesions or neovascularization, which is the later phase of diabetic retinopathy, in computer aided eye disease diagnosis systems. Whereas optic disc detection is fairly an easy process in normal retinal images, detecting this region in the retinal image which is diabetic retinopathy disease may be difficult. Sometimes information related to optic disc and hard exudate information may be the same in terms of machine learning. We presented a novel approach for efficient and accurate localization of optic disc in retinal images having noise and other lesions. This approach is comprised of five main steps which are image processing, keypoint extraction, texture analysis, visual dictionary, and classifier techniques. We tested our proposed technique on 3 public datasets and obtained quantitative results. Experimental results show that an average optic disc detection accuracy of 94.38%, 95.00%, and 90.00% is achieved, respectively, on the following public datasets: DIARETDB1, DRIVE, and ROC.


Author(s):  
Apurv Joshi ◽  
Atharva Kadethankar ◽  
Vedant Patwardhan ◽  
Prasanna Porwal ◽  
Samiksha Pachade ◽  
...  

2020 ◽  
Vol 132 (2) ◽  
pp. 301-305
Author(s):  
Daewook Kim

AbstractThe expression נפשות in Ezekiel 13 refers to two different meanings: (living) human beings and the spirits of the dead. The words כסתות and מספחות seem to refer to the paraphernalia involved in the women’s practice of necromancy and in the fall of the people, respectively. The expression נפשות is employed as antanaclasis to establish a conceptual connection between necromancy and ruin.


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