Transmyocardial Revascularization By CO/sub 2/ Laser: Measurement Of Local Myocardial Temperature And Blood Flow In Acute Ischemic Heart Model

Author(s):  
M. Nakamura ◽  
M. Okada ◽  
Y. Matoba ◽  
Y. Tsuji ◽  
M. Yoshida
2017 ◽  
Vol 312 (1) ◽  
pp. R108-R113 ◽  
Author(s):  
J. R. Caldas ◽  
R. B. Panerai ◽  
V. J. Haunton ◽  
J. P. Almeida ◽  
G. S. R. Ferreira ◽  
...  

Patients with ischemic heart failure (iHF) have a high risk of neurological complications such as cognitive impairment and stroke. We hypothesized that iHF patients have a higher incidence of impaired dynamic cerebral autoregulation (dCA). Adult patients with iHF and healthy volunteers were included. Cerebral blood flow velocity (CBFV, transcranial Doppler, middle cerebral artery), end-tidal CO2 (capnography), and arterial blood pressure (Finometer) were continuously recorded supine for 5 min at rest. Autoregulation index (ARI) was estimated from the CBFV step response derived by transfer function analysis using standard template curves. Fifty-two iHF patients and 54 age-, gender-, and BP-matched healthy volunteers were studied. Echocardiogram ejection fraction was 40 (20–45) % in iHF group. iHF patients compared with control subjects had reduced end-tidal CO2 (34.1 ± 3.7 vs. 38.3 ± 4.0 mmHg, P < 0.001) and lower ARI values (5.1 ± 1.6 vs. 5.9 ± 1.0, P = 0.012). ARI <4, suggestive of impaired CA, was more common in iHF patients (28.8 vs. 7.4%, P = 0.004). These results confirm that iHF patients are more likely to have impaired dCA compared with age-matched controls. The relationship between impaired dCA and neurological complications in iHF patients deserves further investigation.


1988 ◽  
Vol 3 (3) ◽  
pp. 65-72 ◽  
Author(s):  
Massimo Pistolesi ◽  
Massimo Miniati ◽  
Marisa Bonsignore ◽  
Felicita Andreotti ◽  
Giorgio Di Ricco ◽  
...  

1995 ◽  
Vol 25 (2) ◽  
pp. 187A ◽  
Author(s):  
Mathias Knecht ◽  
Sulli Popilskis ◽  
Geng-Hua Yi ◽  
Milton Packer ◽  
Daniel Burkhoff ◽  
...  

Author(s):  
John D. Martin

A computational fluid dynamics (CFD) study has been done comparing pulsatile and non-pulsatile blood flow through the aortic arch and its main branches. The pulsatile flow was to mimic the blood flow due to a beating heart and the non-pulsatile or steady flow was to mimic cardiopulmonary bypass (CPB). The purpose of the study was too narrow in on possible reasons CPB may contribute to the development of atherosclerosis. The main focus of the study was to look at the wall shear stress (WSS) values due to their close association with the development of atherosclerosis. In addition velocity and pressure data were also analyzed. The results of this study showed a stark contrast between the WSS values between the CPB model and the beating heart model. The CPB model did not have any points of oscillating WSS combined with the fact that there were regions of very high and very low constant WSS values in comparison with the beating heart analysis suggests that there may be potential for atherosclerotic development or plaque buildup within the artery. The beating heart model showed a range of WSS values within the aorta that were much lower overall compared with the CPB model.


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