A hybrid fuzzy-neural control system for management of mean arterial pressure of seriously ill patients

2002 ◽  
Author(s):  
Z.M. Xu ◽  
J.S. Packer ◽  
J.F. Cade
Keyword(s):  
Control System ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Neural Control ◽  
Fuzzy Neural ◽  
Seriously Ill Patients ◽  
Seriously Ill

Comparison of the effects of Althesin, chloralose-urethane, urethane, and pentobarbital on mammalian physiologic responses

1984 ◽  
Vol 62 (6) ◽  
pp. 654-657 ◽  
Author(s):  
Melvin Ching
Keyword(s):  
Heart Rate ◽  
Mean Arterial Pressure ◽  
Body Temperature ◽  
Arterial Pressure ◽  
Neural Control ◽  
Core Body Temperature ◽  
Tail Flick ◽  
Tail Flick Test ◽  
Duration Of Action ◽  
Core Body

Physiological responses to anesthetic doses of four chemically dissimilar agents, namely, Althesin, urethane, chloralose-urethane, and pentobarbital sodium were compared in rats. The tail-flick test revealed Althesin had greater antinociceptive potency than urethane, chloralose-urethane, and pentobarbital, but its duration of action was shorter than that of chloralose-urethane. Althesin produced minimal or no suppression of core body temperature and mean arterial pressure, and only moderate reduction of mean pulse pressure. The heart rate and respiratory rate of Althesin-treated rats were slower than those of chloralose-urethane and urethane-treated counterparts, respectively, but were not significantly decreased from normal controls. It is concluded that Althesin is a suitable anesthetic for short-term surgery and for studies of body temperature, heart rate, and mean arterial pressure. Because release of gonadotropin-releasing hormone into hypophysial portal blood can be observed under Althesin but is suppressed or blocked by chloralose-urethane, urethane, and pentobarbital, Althesin is the anesthetic of choice in studies concerned with the neural control of ovulatory hormone release.

Microinjection of vasopressin into the locus coeruleus of conscious rats

1984 ◽  
Vol 247 (4) ◽  
pp. H675-H681 ◽  
Author(s):  
K. H. Berecek ◽  
H. R. Olpe ◽  
R. S. Jones ◽  
K. G. Hofbauer
Keyword(s):  
Heart Rate ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Locus Coeruleus ◽  
Neural Control ◽  
Cardiovascular Responses ◽  
Adrenergic Blockade ◽  
Central Action ◽  
Dose Injection ◽  
Stimulation Of

To determine whether vasopressin plays a role in central neural control of cardiovascular function by acting on the locus coeruleus we monitored arterial pressure and heart rate responses to graded injections of vasopressin (1-30 ng, 0.1-0.3 microliter) in the locus coeruleus of conscious, restrained rats. Cannulas were stereotaxically implanted in the locus coeruleus 2-5 days prior to experiment. Injections of vasopressin into the locus coeruleus produced dose-related increases in mean arterial pressure (12 +/- 2 to 57 +/- 6 mmHg) and heart rate (27 +/- 6 to 123 +/- 16 beats/min), which lasted over 1 h at the highest dose. Injection of the antipressor vasopressin antagonist d(CH2)5Tyr(Me) arginine vasopressin (10 ng) into the locus coeruleus blocked the cardiovascular responses to vasopressin. Administration of vasopressin into an area lateral to the locus coeruleus had no effect on mean arterial pressure but produced an increase in heart rate. Equivalent doses of saline, angiotensin II, and norepinephrine (NE) had minimal or opposite (NE) effects on arterial pressure and heart rate. Peripheral alpha-adrenergic blockade with phentolamine and beta-adrenergic blockade with propranolol blocked the cardiovascular responses to injection of vasopressin in the locus coeruleus. These results suggest that vasopressin may act in the region of the locus coeruleus to exert a central action on the cardiovascular system that is mediated by a stimulation of sympathetic outflow.

A fuzzy neural control system for EDM

2013 ◽  
Author(s):  
Haiyan wang ◽  
◽  
Bai Yu ◽  
Keyword(s):  
Control System ◽  
Neural Control ◽  
Fuzzy Neural
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