Implementation of Dual Tree Complex Wavelet Transform with Mean Energy Features to detect Alzheimer’s Disease

Author(s):  
Neha Garg ◽  
Mahipal Chaudhary
Author(s):  
Prof. Preeti S. Topannavar Et al.

In this paper, a method is suggested for multi directional analysis of Magnetic Resonance Image (MRI) scans for detection of Alzheimer’s disease (AD). This is a novel technique which utilizes, two-dimensional (2-D) rotated complex wavelet filters (RCWF) for feature identification. DTCWT identifies the features in 6 directions (±150±450, ±750) while RCWT identifies the features in different 6 directions (-300,0, +300, +600, +900, +1200), which enhances the directional selectivity of the transform coefficients and results in well description of corresponding textures. Dual-tree rotated complex wavelet transform (DT- RCWF) and dual-tree complex wavelet transform (DT- CWT) are applied to the sample images at a time thus the transform coefficients in twelve different directions is obtained simultaneously. The obtained transform coefficients are used for calculation of various texture features such as energy, entropy and standard deviation. The obtained parameters form the feature vectors which are given as input to the classifiers to get the input classified as Normal control or AD sufferer. This proposed algorithm produces results which are superior in terms of accuracy, feature extraction rate, sensitivity, specificity, precision and recall necessary to realize the efficiency of diagnosis of Alzheimer’s Disease as compared to other existing methods.


2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Debesh Jha ◽  
Ji-In Kim ◽  
Goo-Rak Kwon

Background. Error-free diagnosis of Alzheimer’s disease (AD) from healthy control (HC) patients at an early stage of the disease is a major concern, because information about the condition’s severity and developmental risks present allows AD sufferer to take precautionary measures before irreversible brain damage occurs. Recently, there has been great interest in computer-aided diagnosis in magnetic resonance image (MRI) classification. However, distinguishing between Alzheimer’s brain data and healthy brain data in older adults (age > 60) is challenging because of their highly similar brain patterns and image intensities. Recently, cutting-edge feature extraction technologies have found extensive application in numerous fields, including medical image analysis. Here, we propose a dual-tree complex wavelet transform (DTCWT) for extracting features from an image. The dimensionality of feature vector is reduced by using principal component analysis (PCA). The reduced feature vector is sent to feed-forward neural network (FNN) to distinguish AD and HC from the input MR images. These proposed and implemented pipelines, which demonstrate improvements in classification output when compared to that of recent studies, resulted in high and reproducible accuracy rates of 90.06 ± 0.01% with a sensitivity of 92.00 ± 0.04%, a specificity of 87.78 ± 0.04%, and a precision of 89.6 ± 0.03% with 10-fold cross-validation.


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